Sertraline Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. (Chemical Entities of Biological Interest Ontology, CHEBI_9123)
External Link http://www.hmdb.ca/metabolites/HMDB05010
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Genes

6 interacting proteins for the Sertraline metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4