Severe Depression Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0588008
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Genes

45 genes associated with the disease Severe Depression in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
APOE apolipoprotein E
ATF7IP activating transcription factor 7 interacting protein
BDNF brain-derived neurotrophic factor
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD40LG CD40 ligand
CFLAR CASP8 and FADD-like apoptosis regulator
CRP C-reactive protein, pentraxin-related
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DRD2 dopamine receptor D2
EPO erythropoietin
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL22 interleukin 22
IL6 interleukin 6
IL6R interleukin 6 receptor
KL klotho
LEP leptin
LTBP3 latent transforming growth factor beta binding protein 3
MPI mannose phosphate isomerase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTM1 myotubularin 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NUCB2 nucleobindin 2
PAEP progestagen-associated endometrial protein
PMP22 peripheral myelin protein 22
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TNF tumor necrosis factor
TPH2 tryptophan hydroxylase 2
VEGFA vascular endothelial growth factor A