Sexual Dysfunctions, Psychological Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D020018
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Genes

288 genes/proteins associated with the disease Sexual Dysfunctions, Psychological from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.88009
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.88009
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.88009
GRIK2 glutamate receptor, ionotropic, kainate 2 2.88009
PRL prolactin 2.88009
GRIA1 glutamate receptor, ionotropic, AMPA 1 2.88009
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.32991
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.26041
DRD2 dopamine receptor D2 2.25873
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.22518
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.17836
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.16329
BDNF brain-derived neurotrophic factor 2.16183
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.14672
CAT catalase 2.13867
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.02061
FOS FBJ murine osteosarcoma viral oncogene homolog 2.0202
MAPK3 mitogen-activated protein kinase 3 2.00412
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.00329
CREB1 cAMP responsive element binding protein 1 1.99854
MAPK1 mitogen-activated protein kinase 1 1.99567
TH tyrosine hydroxylase 1.98539
ARC activity-regulated cytoskeleton-associated protein 1.96744
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.91651
CRH corticotropin releasing hormone 1.91368
DRD3 dopamine receptor D3 1.91184
NPY neuropeptide Y 1.90125
DRD1 dopamine receptor D1 1.89796
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.88409
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.87892
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.86907
EGR1 early growth response 1 1.85011
TNF tumor necrosis factor 1.80868
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.77994
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.77452
NOS2 nitric oxide synthase 2, inducible 1.77121
TAC1 tachykinin, precursor 1 1.76694
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.756
SOD1 superoxide dismutase 1, soluble 1.75241
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.71441
INS insulin 1.71193
POMC proopiomelanocortin 1.70657
DUSP1 dual specificity phosphatase 1 1.69254
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.69254
INHBE inhibin, beta E 1.67569
PENK proenkephalin 1.67376
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.67007
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.65227
VEGFA vascular endothelial growth factor A 1.65159
BCL2 B-cell CLL/lymphoma 2 1.64842
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.64168
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.64168
BAX BCL2-associated X protein 1.63676
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.63138
NUPR1 nuclear protein, transcriptional regulator, 1 1.62624
MBP myelin basic protein 1.61529
SREBF1 sterol regulatory element binding transcription factor 1 1.61248
TAGLN transgelin 1.61061
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.60827
HPN hepsin 1.59778
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.59101
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.57618
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.57571
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.57186
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.55822
SNAP25 synaptosomal-associated protein, 25kDa 1.55574
MAPK8 mitogen-activated protein kinase 8 1.55157
C10ORF10 chromosome 10 open reading frame 10 1.55157
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.55108
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.55108
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.5479
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.5479
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.53603
HOMER1 homer scaffolding protein 1 1.52591
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.52287
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.51911
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.51784
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.51481
GSK3B glycogen synthase kinase 3 beta 1.51456
HPCAL1 hippocalcin-like 1 1.49226
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.48454
GAL galanin/GMAP prepropeptide 1.47348
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.46883
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.46754
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.46515
ADRA2A adrenoceptor alpha 2A 1.45883
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.44899
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.44681
FABP1 fatty acid binding protein 1, liver 1.44463
FSHB follicle stimulating hormone, beta polypeptide 1.44409
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.443
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.44166
S100B S100 calcium binding protein B 1.44166
JUNB jun B proto-oncogene 1.43374
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.43347
FNDC4 fibronectin type III domain containing 4 1.42885
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.42535
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.42238
NPPA natriuretic peptide A 1.41938
SGK1 serum/glucocorticoid regulated kinase 1 1.41229
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.41146
RGS9 regulator of G-protein signaling 9 1.41008
JUN jun proto-oncogene 1.40677
SREBF2 sterol regulatory element binding transcription factor 2 1.38974
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.38584
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.38412
FOSL1 FOS-like antigen 1 1.38071
AVP arginine vasopressin 1.3699
ADORA1 adenosine A1 receptor 1.36763
GFAP glial fibrillary acidic protein 1.36735
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.36619
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.36562
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.35676
TP53 tumor protein p53 1.3443
PRKCZ protein kinase C, zeta 1.3414
PRKCA protein kinase C, alpha 1.34053
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.33761
ADRB1 adrenoceptor beta 1 1.33375
FOSL2 FOS-like antigen 2 1.32696
GDNF glial cell derived neurotrophic factor 1.32399
IL1B interleukin 1, beta 1.32251
IGF1 insulin-like growth factor 1 (somatomedin C) 1.31446
RGS3 regulator of G-protein signaling 3 1.31416
FGF2 fibroblast growth factor 2 (basic) 1.30666
PVALB parvalbumin 1.30574
EFNB3 ephrin-B3 1.30543
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.30451
MAOA monoamine oxidase A 1.30056
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.30026
DRD4 dopamine receptor D4 1.29348
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.29317
EGFR epidermal growth factor receptor 1.2898
CCKBR cholecystokinin B receptor 1.28549
PDE4B phosphodiesterase 4B, cAMP-specific 1.28364
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.28303
DCLK1 doublecortin-like kinase 1 1.28149
IL6 interleukin 6 1.27966
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.27409
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.27378
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.27286
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 1.27132
LHB luteinizing hormone beta polypeptide 1.27132
IFNG interferon, gamma 1.2707
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.27009
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.26669
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.26638
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.26421
RELN reelin 1.25588
PRLR prolactin receptor 1.25494
PRKCD protein kinase C, delta 1.25307
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.25245
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.25028
RTN4 reticulon 4 1.24905
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.24874
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.2437
NOS1 nitric oxide synthase 1 (neuronal) 1.24024
MAPK14 mitogen-activated protein kinase 14 1.23775
CCL2 chemokine (C-C motif) ligand 2 1.23584
EGR3 early growth response 3 1.23552
ADRB2 adrenoceptor beta 2, surface 1.23392
BCL2L1 BCL2-like 1 1.2336
FAS Fas cell surface death receptor 1.23201
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 1.23074
STXBP1 syntaxin binding protein 1 1.23042
JUND jun D proto-oncogene 1.23042
ASGR1 asialoglycoprotein receptor 1 1.23042
PLP1 proteolipid protein 1 1.22534
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 1.22339
CTSK cathepsin K 1.21663
PRKCE protein kinase C, epsilon 1.21567
PRKCB protein kinase C, beta 1.2137
MAOB monoamine oxidase B 1.2137
RGS4 regulator of G-protein signaling 4 1.21337
ELK1 ELK1, member of ETS oncogene family 1.20751
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.20427
DPF1 D4, zinc and double PHD fingers family 1 1.20328
MAP2 microtubule-associated protein 2 1.2013
ADCY5 adenylate cyclase 5 1.19999
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.19835
BAD BCL2-associated agonist of cell death 1.19802
GJA1 gap junction protein, alpha 1, 43kDa 1.19246
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.19047
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.18981
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.18424
ALB albumin 1.17761
GSK3A glycogen synthase kinase 3 alpha 1.17695
SYNE1 spectrin repeat containing, nuclear envelope 1 1.17662
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 1.17662
ADIPOQ adiponectin, C1Q and collagen domain containing 1.173
HAO2 hydroxyacid oxidase 2 (long chain) 1.17235
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.17235
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.17067
CNR1 cannabinoid receptor 1 (brain) 1.16733
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.15526
CXCL10 chemokine (C-X-C motif) ligand 10 1.15324
KLF9 Kruppel-like factor 9 1.15223
SYT4 synaptotagmin IV 1.14541
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.14473
CKB creatine kinase, brain 1.14473
GRM1 glutamate receptor, metabotropic 1 1.14336
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.14234
ADORA2A adenosine A2a receptor 1.14234
CREM cAMP responsive element modulator 1.14234
MAPK9 mitogen-activated protein kinase 9 1.142
STX1B syntaxin 1B 1.13793
GRIK3 glutamate receptor, ionotropic, kainate 3 1.13758
MAP1B microtubule-associated protein 1B 1.13552
HRH1 histamine receptor H1 1.13313
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.13279
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.13109
GRIK1 glutamate receptor, ionotropic, kainate 1 1.13109
EPHA7 EPH receptor A7 1.12391
MAP1A microtubule-associated protein 1A 1.12391
MAL mal, T-cell differentiation protein 1.12082
GRM5 glutamate receptor, metabotropic 5 1.12082
IL2 interleukin 2 1.11466
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.1122
HPCAL4 hippocalcin like 4 1.11081
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.11081
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 1.11046
PLLP plasmolipin 1.11046
EDN1 endothelin 1 1.10838
KDR kinase insert domain receptor 1.10596
PPP5C protein phosphatase 5, catalytic subunit 1.10493
MPO myeloperoxidase 1.10211
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.09892
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 1.09857
GRIK5 glutamate receptor, ionotropic, kainate 5 1.09857
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.09332
PDE10A phosphodiesterase 10A 1.09262
PRR18 proline rich 18 1.09226
BIK BCL2-interacting killer (apoptosis-inducing) 1.08975
NGF nerve growth factor (beta polypeptide) 1.08655
CALR calreticulin 1.08442
NPTX2 neuronal pentraxin II 1.08091
SYP synaptophysin 1.07732
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.07696
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1.07589
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.07411
STAT5A signal transducer and activator of transcription 5A 1.07128
PER1 period circadian clock 1 1.07093
BMP7 bone morphogenetic protein 7 1.06479
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.06442
PPARG peroxisome proliferator-activated receptor gamma 1.0637
NPPB natriuretic peptide B 1.0608
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.0608
NUMBL numb homolog (Drosophila)-like 1.05721
KCNIP3 Kv channel interacting protein 3, calsenilin 1.05721
GH1 growth hormone 1 1.05685
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.0561
DDR2 discoidin domain receptor tyrosine kinase 2 1.05386
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.05386
IRS1 insulin receptor substrate 1 1.05312
NTS neurotensin 1.05015
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.04978
PDE4A phosphodiesterase 4A, cAMP-specific 1.04941
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.04868
NGFR nerve growth factor receptor 1.04757
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.04757
ODC1 ornithine decarboxylase 1 1.04611
CHGA chromogranin A 1.04427
CCK cholecystokinin 1.04201
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.03939
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.03864
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.03604
LPL lipoprotein lipase 1.03419
HCRTR2 hypocretin (orexin) receptor 2 1.03382
PTK2B protein tyrosine kinase 2 beta 1.03345
LDHB lactate dehydrogenase B 1.03084
GATA3 GATA binding protein 3 1.03046
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.03009
POR P450 (cytochrome) oxidoreductase 1.02933
CRYAB crystallin, alpha B 1.02896
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.02522
NCAN neurocan 1.02485
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.02485
CARTPT CART prepropeptide 1.02114
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.0204
CLIC1 chloride intracellular channel 1 1.0204
PDYN prodynorphin 1.02003
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.01739
JAK1 Janus kinase 1 1.01739
HDAC5 histone deacetylase 5 1.01625
CCND1 cyclin D1 1.01512
DCAF6 DDB1 and CUL4 associated factor 6 1.01512
CBLN1 cerebellin 1 precursor 1.01399
DUSP8 dual specificity phosphatase 8 1.01249
PRKCG protein kinase C, gamma 1.01212