Sezary Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0036920
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Genes

179 genes associated with the disease Sezary Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AHI1 Abelson helper integration site 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA5 annexin A5
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID1A AT rich interactive domain 1A (SWI-like)
ARRB2 arrestin, beta 2
ASCC1 activating signal cointegrator 1 complex subunit 1
ATM ATM serine/threonine kinase
BCL10 B-cell CLL/lymphoma 10
BCR breakpoint cluster region
BIN1 bridging integrator 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD9 bromodomain containing 9
CADM1 cell adhesion molecule 1
CARD11 caspase recruitment domain family, member 11
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL17 chemokine (C-C motif) ligand 17
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR10 chemokine (C-C motif) receptor 10
CCR4 chemokine (C-C motif) receptor 4
CCR7 chemokine (C-C motif) receptor 7
CD164 CD164 molecule, sialomucin
CD28 CD28 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDO1 cysteine dioxygenase type 1
CHD3 chromodomain helicase DNA binding protein 3
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
CREBBP CREB binding protein
CRISP2 cysteine-rich secretory protein 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
EBI3 Epstein-Barr virus induced 3
EPHA4 EPH receptor A4
ERBB2 erb-b2 receptor tyrosine kinase 2
FAS Fas cell surface death receptor
FCRL3 Fc receptor-like 3
FGFR1 fibroblast growth factor receptor 1
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
HELLS helicase, lymphoid-specific
HHEX hematopoietically expressed homeobox
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HM13 histocompatibility (minor) 13
HRAS Harvey rat sarcoma viral oncogene homolog
IER3 immediate early response 3
IFNG interferon, gamma
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL18R1 interleukin 18 receptor 1
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL25 interleukin 25
IL2RG interleukin 2 receptor, gamma
IL31 interleukin 31
IL32 interleukin 32
IL4 interleukin 4
IL5 interleukin 5
IL7 interleukin 7
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLHL42 kelch-like family member 42
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KRAS Kirsten rat sarcoma viral oncogene homolog
LBR lamin B receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
MAPK1 mitogen-activated protein kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTAP methylthioadenosine phosphorylase
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYDGF myeloid-derived growth factor
NAV3 neuron navigator 3
NCR1 natural cytotoxicity triggering receptor 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKG7 natural killer cell granule protein 7
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAM peptidylglycine alpha-amidating monooxygenase
PARP1 poly (ADP-ribose) polymerase 1
PDCD10 programmed cell death 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCG1 phospholipase C, gamma 1
PLS3 plastin 3
POT1 protection of telomeres 1
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKG1 protein kinase, cGMP-dependent, type I
PRSS55 protease, serine, 55
PTEN phosphatase and tensin homolog
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG2 recombination activating gene 2
RB1 retinoblastoma 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRBP1 ribosome binding protein 1
RTEL1 regulator of telomere elongation helicase 1
RUNX3 runt-related transcription factor 3
SATB1 SATB homeobox 1
SDC4 syndecan 4
SELL selectin L
SELPLG selectin P ligand
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLFN12 schlafen family member 12
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SOAT1 sterol O-acyltransferase 1
SOCS3 suppressor of cytokine signaling 3
SPZ1 spermatogenic leucine zipper 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TAC1 tachykinin, precursor 1
TBX21 T-box 21
TCF3 transcription factor 3
TET2 tet methylcytosine dioxygenase 2
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
TSPYL2 TSPY-like 2
TWIST1 twist family bHLH transcription factor 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF217 zinc finger protein 217