Shc-Grb2-mSos1 complex, EGF stimulated Gene Set

Dataset CORUM Protein Complexes
Category structural or functional annotations
Type protein complex
Description A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. (Gene Ontology, GO_0070619)
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3 proteins in the Shc-Grb2-mSos1 complex, EGF stimulated protein complex from the CORUM Protein Complexes dataset.

Symbol Name
GRB2 growth factor receptor-bound protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)