SiHa Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

303 genes with high or low expression in SiHa relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 3.58995
SF3B3 splicing factor 3b, subunit 3, 130kDa 3.37321
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 3.2208
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 2.83734
ACD adrenocortical dysplasia homolog (mouse) 2.82525
ZC3H12A zinc finger CCCH-type containing 12A 2.81848
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.76424
RFWD3 ring finger and WD repeat domain 3 2.68783
FBXO2 F-box protein 2 2.67968
CHMP1A charged multivesicular body protein 1A 2.65419
PEX19 peroxisomal biogenesis factor 19 2.63208
ADAT1 adenosine deaminase, tRNA-specific 1 2.59718
PRDM8 PR domain containing 8 2.5555
RASIP1 Ras interacting protein 1 2.50335
PRMT7 protein arginine methyltransferase 7 2.49439
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.42271
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.38055
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.33482
CNOT1 CCR4-NOT transcription complex, subunit 1 2.26898
DEXI Dexi homolog (mouse) 2.25623
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.24378
SNAI1 snail family zinc finger 1 2.2313
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.22843
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 2.21404
PMM1 phosphomannomutase 1 2.19355
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.18959
ZNF174 zinc finger protein 174 2.17111
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.16
CSF3 colony stimulating factor 3 (granulocyte) 2.15883
MCM4 minichromosome maintenance complex component 4 2.12683
ADARB1 adenosine deaminase, RNA-specific, B1 2.09885
TSNAXIP1 translin-associated factor X interacting protein 1 2.09619
LCAT lecithin-cholesterol acyltransferase 2.08396
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 2.07879
EMC8 ER membrane protein complex subunit 8 2.06836
COG4 component of oligomeric golgi complex 4 2.05889
WDR70 WD repeat domain 70 2.04818
RANBP10 RAN binding protein 10 2.04315
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.04229
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.03257
THAP11 THAP domain containing 11 2.0104
EDC4 enhancer of mRNA decapping 4 2.00204
DTWD1 DTW domain containing 1 1.99837
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.99693
COMMD4 COMM domain containing 4 1.9924
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 1.98516
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 1.98274
IL6 interleukin 6 1.97903
SNTA1 syntrophin, alpha 1 1.97032
NUTF2 nuclear transport factor 2 1.96825
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.95492
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.93381
PAQR4 progestin and adipoQ receptor family member IV 1.91822
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.91704
SIK1 salt-inducible kinase 1 1.91697
E2F4 E2F transcription factor 4, p107/p130-binding 1.91644
ATMIN ATM interactor 1.9025
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 1.87938
CEMIP cell migration inducing protein, hyaluronan binding 1.87492
FBXO31 F-box protein 31 1.87016
STEAP4 STEAP family member 4 1.85595
MLYCD malonyl-CoA decarboxylase 1.84303
MEPCE methylphosphate capping enzyme 1.84126
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 1.82296
UBE2A ubiquitin-conjugating enzyme E2A 1.80983
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.8088
EFNA1 ephrin-A1 1.80729
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.80574
BCL3 B-cell CLL/lymphoma 3 1.78894
DIO2 deiodinase, iodothyronine, type II 1.78568
SAR1A secretion associated, Ras related GTPase 1A 1.78064
TTC12 tetratricopeptide repeat domain 12 1.77787
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.76577
TK2 thymidine kinase 2, mitochondrial 1.76418
PTPN9 protein tyrosine phosphatase, non-receptor type 9 1.75477
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 1.74449
GAS8 growth arrest-specific 8 1.74087
CD14 CD14 molecule 1.7347
OXCT1 3-oxoacid CoA transferase 1 1.73243
PARN poly(A)-specific ribonuclease 1.72859
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.72421
LTB4R leukotriene B4 receptor 1.71787
VTN vitronectin 1.71758
TPRA1 transmembrane protein, adipocyte asscociated 1 1.71343
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.71291
MYO19 myosin XIX 1.71254
MTF1 metal-regulatory transcription factor 1 1.71216
NECAP2 NECAP endocytosis associated 2 1.71007
CDK5RAP1 CDK5 regulatory subunit associated protein 1 1.69742
ALAS2 5'-aminolevulinate synthase 2 1.6823
TCF25 transcription factor 25 (basic helix-loop-helix) 1.6753
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.66793
ACSL4 acyl-CoA synthetase long-chain family member 4 1.65468
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.64986
ANKRD11 ankyrin repeat domain 11 1.64627
IER2 immediate early response 2 1.63543
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 1.63208
ADCY3 adenylate cyclase 3 1.62545
CENPN centromere protein N 1.62309
EGR4 early growth response 4 1.61952
TTLL5 tubulin tyrosine ligase-like family member 5 1.60602
NIPBL Nipped-B homolog (Drosophila) 1.60549
STC1 stanniocalcin 1 1.60491
CTSF cathepsin F 1.59468
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.59319
KIFC3 kinesin family member C3 1.59088
CDT1 chromatin licensing and DNA replication factor 1 1.59009
ACTC1 actin, alpha, cardiac muscle 1 1.58915
DMC1 DNA meiotic recombinase 1 1.57685
SIPA1L1 signal-induced proliferation-associated 1 like 1 1.57417
JUNB jun B proto-oncogene 1.57339
STAU1 staufen double-stranded RNA binding protein 1 1.56603
ZBTB35 zinc finger and BTB domain containing 35 1.56441
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 1.55929
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.55631
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 1.55581
SYCP2 synaptonemal complex protein 2 1.5548
CES2 carboxylesterase 2 1.55436
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 1.55276
VAC14 Vac14 homolog (S. cerevisiae) 1.55244
G0S2 G0/G1 switch 2 1.55139
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.54919
SECTM1 secreted and transmembrane 1 1.54486
NUP93 nucleoporin 93kDa 1.5406
SPAG4 sperm associated antigen 4 1.53989
UBA1 ubiquitin-like modifier activating enzyme 1 1.53647
PQLC2 PQ loop repeat containing 2 1.53458
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 1.53389
DNAH2 dynein, axonemal, heavy chain 2 1.53128
JOSD1 Josephin domain containing 1 1.53059
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.52865
MUC8 mucin 8 1.52261
CDC25C cell division cycle 25C 1.52132
CIAPIN1 cytokine induced apoptosis inhibitor 1 1.5193
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.51156
RYR1 ryanodine receptor 1 (skeletal) 1.51091
BTBD1 BTB (POZ) domain containing 1 1.50916
FAM96B family with sequence similarity 96, member B 1.50891
KYNU kynureninase 1.50419
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 1.50165
SPA17 sperm autoantigenic protein 17 1.50091
GAREM GRB2 associated, regulator of MAPK1 1.49587
BAG1 BCL2-associated athanogene 1.48477
PC pyruvate carboxylase 1.48123
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 1.47742
TXNRD3 thioredoxin reductase 3 1.47659
TNNI1 troponin I type 1 (skeletal, slow) 1.47607
TACR1 tachykinin receptor 1 1.47179
HIC1 hypermethylated in cancer 1 1.4694
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 1.46881
BANP BTG3 associated nuclear protein 1.46683
FOXB1 forkhead box B1 1.46669
TIMP1 TIMP metallopeptidase inhibitor 1 1.46503
NXF1 nuclear RNA export factor 1 1.46369
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.46263
E4F1 E4F transcription factor 1 1.46224
MCM3AP minichromosome maintenance complex component 3 associated protein 1.4595
PLA2G15 phospholipase A2, group XV 1.45707
SYT12 synaptotagmin XII 1.45358
SIVA1 SIVA1, apoptosis-inducing factor 1.4525
ATPIF1 ATPase inhibitory factor 1 1.44566
TERF2 telomeric repeat binding factor 2 1.44445
CD1B CD1b molecule 1.44324
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.44044
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.43869
PXMP2 peroxisomal membrane protein 2, 22kDa 1.43611
CSNK1E casein kinase 1, epsilon 1.43551
TRADD TNFRSF1A-associated via death domain 1.43541
MCM5 minichromosome maintenance complex component 5 1.43264
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 1.43081
PKM pyruvate kinase, muscle 1.42926
ORC1 origin recognition complex, subunit 1 1.42834
GINS2 GINS complex subunit 2 (Psf2 homolog) 1.42675
COQ9 coenzyme Q9 1.42138
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.41877
C1RL complement component 1, r subcomponent-like 1.41864
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 1.41763

low expression

Symbol Name Standardized Value
TRIP12 thyroid hormone receptor interactor 12 -3.53725
CCNG1 cyclin G1 -3.53725
KIAA1109 KIAA1109 -3.52063
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -3.11214
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -2.93923
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.79997
METTL8 methyltransferase like 8 -2.73341
MAGED1 melanoma antigen family D1 -2.6344
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -2.62997
RABGGTB Rab geranylgeranyltransferase, beta subunit -2.45267
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase -2.36045
AKAP1 A kinase (PRKA) anchor protein 1 -2.3422
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -2.33604
SCN11A sodium channel, voltage gated, type XI alpha subunit -2.31194
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.2888
MAP6D1 MAP6 domain containing 1 -2.25682
FOLR1 folate receptor 1 (adult) -2.20584
KAT8 K(lysine) acetyltransferase 8 -2.20264
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -2.16641
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.14047
PRB4 proline-rich protein BstNI subfamily 4 -2.13291
GSR glutathione reductase -2.13012
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.08528
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -2.05928
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -2.05172
RBM12B RNA binding motif protein 12B -2.0342
STAU2 staufen double-stranded RNA binding protein 2 -2.02914
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.02183
DEPTOR DEP domain containing MTOR-interacting protein -2.00722
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -1.99847
GNRHR gonadotropin-releasing hormone receptor -1.98727
PRR5 proline rich 5 (renal) -1.97451
CRYZ crystallin, zeta (quinone reductase) -1.97422
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -1.97344
SATB1 SATB homeobox 1 -1.95991
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -1.95521
ANGPTL2 angiopoietin-like 2 -1.92263
SLC25A38 solute carrier family 25, member 38 -1.8919
MAGEH1 melanoma antigen family H1 -1.88295
ATRNL1 attractin-like 1 -1.87732
EML4 echinoderm microtubule associated protein like 4 -1.87694
RRH retinal pigment epithelium-derived rhodopsin homolog -1.87295
GSTM4 glutathione S-transferase mu 4 -1.86807
COQ3 coenzyme Q3 methyltransferase -1.83229
CADM4 cell adhesion molecule 4 -1.82861
MDN1 MDN1, midasin homolog (yeast) -1.8243
N4BP2L2-IT2 N4BPL2 intronic transcript 2 -1.82089
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase -1.81804
PSG1 pregnancy specific beta-1-glycoprotein 1 -1.80589
FXYD3 FXYD domain containing ion transport regulator 3 -1.80186
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -1.78734
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -1.77797
TBCC tubulin folding cofactor C -1.76907
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -1.76503
RIMS2 regulating synaptic membrane exocytosis 2 -1.75971
NCBP2 nuclear cap binding protein subunit 2, 20kDa -1.75884
ACAA2 acetyl-CoA acyltransferase 2 -1.75771
PHF2 PHD finger protein 2 -1.74916
COIL coilin -1.73263
E2F5 E2F transcription factor 5, p130-binding -1.73069
ZNF91 zinc finger protein 91 -1.72839
CCNH cyclin H -1.72538
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -1.72322
OSBPL9 oxysterol binding protein-like 9 -1.71941
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -1.7177
NOAZFP nucleolar atypical zinc finger -1.71372
MTM1 myotubularin 1 -1.70616
ZNF467 zinc finger protein 467 -1.6994
MTMR6 myotubularin related protein 6 -1.69078
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -1.68708
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.67751
ZSCAN12 zinc finger and SCAN domain containing 12 -1.67383
LIAS lipoic acid synthetase -1.67244
ZNF37BP zinc finger protein 37B, pseudogene -1.66706
ZFAND5 zinc finger, AN1-type domain 5 -1.66021
SH3PXD2A SH3 and PX domains 2A -1.64862
NHEJ1 nonhomologous end-joining factor 1 -1.64356
TSC22D2 TSC22 domain family, member 2 -1.63953
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.63462
TRAK1 trafficking protein, kinesin binding 1 -1.62599
RGS5 regulator of G-protein signaling 5 -1.62223
LRRC37A leucine rich repeat containing 37A -1.61985
POU3F2 POU class 3 homeobox 2 -1.61489
PTPRG protein tyrosine phosphatase, receptor type, G -1.61301
CUTC cutC copper transporter -1.61176
CLN3 ceroid-lipofuscinosis, neuronal 3 -1.6026
STAP2 signal transducing adaptor family member 2 -1.60034
LYPLA1 lysophospholipase I -1.59723
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -1.59545
TMUB2 transmembrane and ubiquitin-like domain containing 2 -1.59166
AARSD1 alanyl-tRNA synthetase domain containing 1 -1.5846
SERHL serine hydrolase-like (pseudogene) -1.57887
FMO5 flavin containing monooxygenase 5 -1.5737
FLJ20712 uncharacterized FLJ20712 -1.57065
GPR39 G protein-coupled receptor 39 -1.57037
OXR1 oxidation resistance 1 -1.56358
DAPK3 death-associated protein kinase 3 -1.55546
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -1.54604
USH1C Usher syndrome 1C (autosomal recessive, severe) -1.53436
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 -1.53407
MPV17 MpV17 mitochondrial inner membrane protein -1.52477
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -1.52234
DPYS dihydropyrimidinase -1.51977
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -1.51687
ADAM21 ADAM metallopeptidase domain 21 -1.51557
SLC2A3P1 solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 -1.51
IDS iduronate 2-sulfatase -1.50404
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 -1.49769
GADD45A growth arrest and DNA-damage-inducible, alpha -1.49504
HAND1 heart and neural crest derivatives expressed 1 -1.48999
ANK2 ankyrin 2, neuronal -1.48635
DSPP dentin sialophosphoprotein -1.48197
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -1.47799
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 -1.47353
ARMC4 armadillo repeat containing 4 -1.47311
STAB2 stabilin 2 -1.46862
MAGEA12 melanoma antigen family A12 -1.46083
NEK11 NIMA-related kinase 11 -1.45746
STK17B serine/threonine kinase 17b -1.45683
USPL1 ubiquitin specific peptidase like 1 -1.44456
RGS1 regulator of G-protein signaling 1 -1.44296
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -1.43963
FKSG49 FKSG49 -1.42998
BGN biglycan -1.42849
ATP11A ATPase, class VI, type 11A -1.42142
SLC39A9 solute carrier family 39, member 9 -1.41602