Sicca Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0086981
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Genes

124 genes associated with the disease Sicca Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACR acrosin
ADIPOQ adiponectin, C1Q and collagen domain containing
AIRE autoimmune regulator
ALB albumin
AQP5 aquaporin 5
AQP8 aquaporin 8
AQP9 aquaporin 9
ARR3 arrestin 3, retinal (X-arrestin)
ATF7IP activating transcription factor 7 interacting protein
B2M beta-2-microglobulin
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP6 bone morphogenetic protein 6
CASR calcium-sensing receptor
CCL25 chemokine (C-C motif) ligand 25
CCR7 chemokine (C-C motif) receptor 7
CCR9 chemokine (C-C motif) receptor 9
CFB complement factor B
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DGKQ diacylglycerol kinase, theta 110kDa
DYM dymeclin
E2F1 E2F transcription factor 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F5 coagulation factor V (proaccelerin, labile factor)
FAM167A family with sequence similarity 167, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCRL4 Fc receptor-like 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FURIN furin (paired basic amino acid cleaving enzyme)
GDF6 growth differentiation factor 6
GLO1 glyoxalase I
GTF2I general transcription factor IIi
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HMOX1 heme oxygenase 1
HPSE heparanase
ICAM1 intercellular adhesion molecule 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IL10 interleukin 10
IL12A interleukin 12A
IL12RB1 interleukin 12 receptor, beta 1
IL17A interleukin 17A
IL1B interleukin 1, beta
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL5 interleukin 5
IL7 interleukin 7
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITSN2 intersectin 2
LBR lamin B receptor
LYZ lysozyme
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MDK midkine (neurite growth-promoting factor 2)
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
NCF1 neutrophil cytosolic factor 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR1I3 nuclear receptor subfamily 1, group I, member 3
PC pyruvate carboxylase
PHIP pleckstrin homology domain interacting protein
PLS3 plastin 3
PMCH pro-melanin-concentrating hormone
PRDM1 PR domain containing 1, with ZNF domain
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTN pleiotrophin
PTTG1 pituitary tumor-transforming 1
PUF60 poly-U binding splicing factor 60KDa
RAD23B RAD23 homolog B (S. cerevisiae)
RBP4 retinol binding protein 4, plasma
RORC RAR-related orphan receptor C
SELE selectin E
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
TACR1 tachykinin receptor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THBS1 thrombospondin 1
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TRAF3IP2 TRAF3 interacting protein 2
TRIM13 tripartite motif containing 13
TSPYL2 TSPY-like 2
VCAM1 vascular cell adhesion molecule 1
VTCN1 V-set domain containing T cell activation inhibitor 1