Sick Sinus Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Xref MGI. (Human Disease Ontology, DOID_13884)
External Link https://www.disgenet.org/browser/0/1/0/C0037052
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Genes

51 genes associated with the disease Sick Sinus Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP9 A kinase (PRKA) anchor protein 9
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CCL2 chemokine (C-C motif) ligand 2
CCN2 cellular communication network factor 2
COL1A2 collagen, type I, alpha 2
FBN1 fibrillin 1
FGFR3 fibroblast growth factor receptor 3
FN1 fibronectin 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC4 histone deacetylase 4
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL6 interleukin 6
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
LMNA lamin A/C
MECP2 methyl CpG binding protein 2
MEF2C myocyte enhancer factor 2C
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
PDCD1 programmed cell death 1
PKP2 plakophilin 2
POMC proopiomelanocortin
RANGRF RAN guanine nucleotide release factor
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN2B sodium channel, voltage gated, type II beta subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SGO1 shugoshin 1
SLMAP sarcolemma associated protein
TBX18 T-box 18
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TTN titin
TXN2 thioredoxin 2
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A