Sickle Cell-Ss Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4321477
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Genes

58 genes associated with the disease Sickle Cell-Ss Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ANTXR1 anthrax toxin receptor 1
AVP arginine vasopressin
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD37 CD37 molecule
CRISP2 cysteine-rich secretory protein 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
EDN1 endothelin 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F5 coagulation factor V (proaccelerin, labile factor)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FN1 fibronectin 1
G6PD glucose-6-phosphate dehydrogenase
GAL3ST1 galactose-3-O-sulfotransferase 1
GDF15 growth differentiation factor 15
GSR glutathione reductase
HAMP hepcidin antimicrobial peptide
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HP haptoglobin
ICAM1 intercellular adhesion molecule 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
KDM1A lysine (K)-specific demethylase 1A
KL klotho
LGALS3 lectin, galactoside-binding, soluble, 3
MFGE8 milk fat globule-EGF factor 8 protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYB v-myb avian myeloblastosis viral oncogene homolog
NFE2L2 nuclear factor, erythroid 2-like 2
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PC pyruvate carboxylase
PDE5A phosphodiesterase 5A, cGMP-specific
PGF placental growth factor
PPARG peroxisome proliferator-activated receptor gamma
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRSS55 protease, serine, 55
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REN renin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN2A sodium channel, voltage gated, type II alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPZ1 spermatogenic leucine zipper 1
STK3 serine/threonine kinase 3
THBS1 thrombospondin 1
TNNI3 troponin I type 3 (cardiac)
UBL4A ubiquitin-like 4A
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VCAM1 vascular cell adhesion molecule 1