Signaling by ALK Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-201556
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Genes

30 proteins participating in the Signaling by ALK pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ALK anaplastic lymphoma receptor tyrosine kinase
ALKAL1 ALK and LTK ligand 1
ALKAL2 ALK and LTK ligand 2
CD274 CD274 molecule
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EP300 E1A binding protein p300
FRS2 fibroblast growth factor receptor substrate 2
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL2RG interleukin 2 receptor, gamma
IRS1 insulin receptor substrate 1
JAK3 Janus kinase 3
MDK midkine (neurite growth-promoting factor 2)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG1 phospholipase C, gamma 1
PRDM1 PR domain containing 1, with ZNF domain
PTN pleiotrophin
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIN3A SIN3 transcription regulator family member A
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)