Signaling by EGFR Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-177929
Similar Terms
Downloads & Tools

Genes

53 proteins participating in the Signaling by EGFR pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AAMP angio-associated, migratory cell protein
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
AREG amphiregulin
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
BTC betacellulin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC42 cell division cycle 42
CSK c-src tyrosine kinase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPGN epithelial mitogen
EPN1 epsin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EREG epiregulin
GAB1 GRB2-associated binding protein 1
GRB2 growth factor receptor-bound protein 2
HBEGF heparin-binding EGF-like growth factor
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HRAS Harvey rat sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
RPS27A ribosomal protein S27a
SACK1A scaffolding CK1 anchoring protein A
SACK1B scaffolding CK1 anchoring protein B
SACK1D scaffolding CK1 anchoring protein D
SH3GL1 SH3-domain GRB2-like 1
SH3GL2 SH3-domain GRB2-like 2
SH3GL3 SH3-domain GRB2-like 3
SH3KBP1 SH3-domain kinase binding protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TGFA transforming growth factor, alpha
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C