Signaling by ERBB2 Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-1227986
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Genes

50 proteins participating in the Signaling by ERBB2 pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
BTC betacellulin
CDC37 cell division cycle 37
CUL5 cullin 5
DIAPH1 diaphanous-related formin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERBIN erbb2 interacting protein
EREG epiregulin
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
HBEGF heparin-binding EGF-like growth factor
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
MATK megakaryocyte-associated tyrosine kinase
MEMO1 mediator of cell motility 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PTK6 protein tyrosine kinase 6
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RHOA ras homolog family member A
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
USP8 ubiquitin specific peptidase 8
YES1 YES proto-oncogene 1, Src family tyrosine kinase