Signaling by FLT3 ITD and TKD mutants Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9703648
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Genes

16 proteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset.

Symbol Name
BCL2L1 BCL2-like 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
FLT3 fms-related tyrosine kinase 3
GAB2 GRB2-associated binding protein 2
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
NOX4 NADPH oxidase 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SOS1 son of sevenless homolog 1 (Drosophila)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B