Signaling by NOTCH Gene Set

Dataset Reactome Pathways 2014
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-157118
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Genes

122 proteins participating in the Signaling by NOTCH pathway from the Reactome Pathways dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CCNC cyclin C
CCND1 cyclin D1
CDK8 cyclin-dependent kinase 8
CNTN1 contactin 1
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CUL1 cullin 1
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNER delta/notch-like EGF repeat containing
DTX1 deltex 1, E3 ubiquitin ligase
DTX2 deltex 2, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EP300 E1A binding protein p300
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FURIN furin (paired basic amino acid cleaving enzyme)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HDAC1 histone deacetylase 1
HDAC10 histone deacetylase 10
HDAC11 histone deacetylase 11
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HDAC7 histone deacetylase 7
HDAC8 histone deacetylase 8
HDAC9 histone deacetylase 9
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ITCH itchy E3 ubiquitin protein ligase
JAG1 jagged 1
JAG2 jagged 2
JUN jun proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAMLD1 mastermind-like domain containing 1
MDK midkine (neurite growth-promoting factor 2)
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIB2 mindbomb E3 ubiquitin protein ligase 2
MIR150 microRNA 150
MIR181C microRNA 181c
MIR200B microRNA 200b
MIR200C microRNA 200c
MIR206 microRNA 206
MIR302A microRNA 302a
MIR34A microRNA 34a
MIR34B microRNA 34b
MIR34C microRNA 34c
MIR449A microRNA 449a
MIR449B microRNA 449b
MIR449C microRNA 449c
MOV10 Mov10 RISC complex RNA helicase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUMB numb homolog (Drosophila)
POFUT1 protein O-fucosyltransferase 1
POGLUT1 protein O-glucosyltransferase 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
RAB6A RAB6A, member RAS oncogene family
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBX1 ring-box 1, E3 ubiquitin protein ligase
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPS27A ribosomal protein S27a
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SKP1 S-phase kinase-associated protein 1
SNW1 SNW domain containing 1
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TLE3 transducin-like enhancer of split 3
TLE4 transducin-like enhancer of split 4
TMED2 transmembrane emp24 domain trafficking protein 2
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TNRC6C trinucleotide repeat containing 6C
TP53 tumor protein p53
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C