Signaling by NTRK1 (TRKA) Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-187037
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Genes

115 proteins participating in the Signaling by NTRK1 (TRKA) pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADORA2A adenosine A2a receptor
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ASCL1 achaete-scute family bHLH transcription factor 1
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CHD4 chromodomain helicase DNA binding protein 4
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DNAL4 dynein, axonemal, light chain 4
DNM1 dynamin 1
DNM2 dynamin 2
DNM3 dynamin 3
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EGR4 early growth response 4
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FRS2 fibroblast growth factor receptor substrate 2
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KIDINS220 kinase D-interacting substrate, 220kDa
KRAS Kirsten rat sarcoma viral oncogene homolog
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NGF nerve growth factor (beta polypeptide)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG1 phospholipase C, gamma 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RALGDS ral guanine nucleotide dissociation stimulator
RAP1A RAP1A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
REST RE1-silencing transcription factor
RHOA ras homolog family member A
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRAD Ras-related associated with diabetes
SGK1 serum/glucocorticoid regulated kinase 1
SH3GL2 SH3-domain GRB2-like 2
SH3GL3 SH3-domain GRB2-like 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TCF12 transcription factor 12
TF transferrin
TPH1 tryptophan hydroxylase 1
TRIB1 tribbles pseudokinase 1
VGF VGF nerve growth factor inducible
VRK3 vaccinia related kinase 3
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta