Signaling by PTK6 Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8848021
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Genes

53 proteins participating in the Signaling by PTK6 pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP35 Rho GTPase activating protein 35
BCAR1 breast cancer anti-estrogen resistance 1
BTC betacellulin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CCNE1 cyclin E1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DOCK1 dedicator of cytokinesis 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELMO1 engulfment and cell motility 1
ELMO2 engulfment and cell motility 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
GPNMB glycoprotein (transmembrane) nmb
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HRAS Harvey rat sarcoma viral oncogene homolog
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LRRK2 leucine-rich repeat kinase 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
PELP1 proline, glutamate and leucine rich protein 1
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RHOA ras homolog family member A
RPS27A ribosomal protein S27a
SFPQ splicing factor proline/glutamine-rich
SOCS3 suppressor of cytokine signaling 3
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
STAP2 signal transducing adaptor family member 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C