Signaling by Rho GTPases Gene Set

Dataset Reactome Pathways 2014
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-194315
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Genes

121 proteins participating in the Signaling by Rho GTPases pathway from the Reactome Pathways dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABR active BCR-related
AKAP13 A kinase (PRKA) anchor protein 13
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP1 Rho GTPase activating protein 1
ARHGAP10 Rho GTPase activating protein 10
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP12 Rho GTPase activating protein 12
ARHGAP15 Rho GTPase activating protein 15
ARHGAP17 Rho GTPase activating protein 17
ARHGAP18 Rho GTPase activating protein 18
ARHGAP19 Rho GTPase activating protein 19
ARHGAP20 Rho GTPase activating protein 20
ARHGAP22 Rho GTPase activating protein 22
ARHGAP23 Rho GTPase activating protein 23
ARHGAP24 Rho GTPase activating protein 24
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ARHGAP29 Rho GTPase activating protein 29
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGAP32 Rho GTPase activating protein 32
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARHGAP36 Rho GTPase activating protein 36
ARHGAP39 Rho GTPase activating protein 39
ARHGAP4 Rho GTPase activating protein 4
ARHGAP40 Rho GTPase activating protein 40
ARHGAP44 Rho GTPase activating protein 44
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGAP8 Rho GTPase activating protein 8
ARHGAP9 Rho GTPase activating protein 9
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
BCR breakpoint cluster region
CDC42 cell division cycle 42
CHN1 chimerin 1
CHN2 chimerin 2
DEPDC1B DEP domain containing 1B
DEPDC7 DEP domain containing 7
DLC1 DLC1 Rho GTPase activating protein
ECT2 epithelial cell transforming 2
FAM13A family with sequence similarity 13, member A
FAM13B family with sequence similarity 13, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
GDI1 GDP dissociation inhibitor 1
GDI2 GDP dissociation inhibitor 2
GMIP GEM interacting protein
HMHA1 histocompatibility (minor) HA-1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITSN1 intersectin 1 (SH3 domain protein)
KALRN kalirin, RhoGEF kinase
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MYO9A myosin IXA
MYO9B myosin IXB
NET1 neuroepithelial cell transforming 1
NGEF neuronal guanine nucleotide exchange factor
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCRL oculocerebrorenal syndrome of Lowe
OPHN1 oligophrenin 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RACGAP1 Rac GTPase activating protein 1
RALBP1 ralA binding protein 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOF ras homolog family member F (in filopodia)
RHOG ras homolog family member G
RHOH ras homolog family member H
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RHOU ras homolog family member U
RHOV ras homolog family member V
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAGAP T-cell activation RhoGTPase activating protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TRIO trio Rho guanine nucleotide exchange factor
TRIP10 thyroid hormone receptor interactor 10
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor