Signaling by Rho GTPases Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-194315
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Genes

672 proteins participating in the Signaling by Rho GTPases pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABR active BCR-related
ACBD5 acyl-CoA binding domain containing 5
ACTB actin, beta
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADD3 adducin 3 (gamma)
AHCTF1 AT hook containing transcription factor 1
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMIGO2 adhesion molecule with Ig-like domain 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKRD26 ankyrin repeat domain 26
ANLN anillin, actin binding protein
AR androgen receptor
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP1 Rho GTPase activating protein 1
ARHGAP10 Rho GTPase activating protein 10
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP12 Rho GTPase activating protein 12
ARHGAP15 Rho GTPase activating protein 15
ARHGAP17 Rho GTPase activating protein 17
ARHGAP18 Rho GTPase activating protein 18
ARHGAP19 Rho GTPase activating protein 19
ARHGAP20 Rho GTPase activating protein 20
ARHGAP21 Rho GTPase activating protein 21
ARHGAP22 Rho GTPase activating protein 22
ARHGAP23 Rho GTPase activating protein 23
ARHGAP24 Rho GTPase activating protein 24
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
ARHGAP27 Rho GTPase activating protein 27
ARHGAP28 Rho GTPase activating protein 28
ARHGAP29 Rho GTPase activating protein 29
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGAP32 Rho GTPase activating protein 32
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARHGAP39 Rho GTPase activating protein 39
ARHGAP4 Rho GTPase activating protein 4
ARHGAP40 Rho GTPase activating protein 40
ARHGAP42 Rho GTPase activating protein 42
ARHGAP44 Rho GTPase activating protein 44
ARHGAP45 Rho GTPase activating protein 45
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGAP8 Rho GTPase activating protein 8
ARHGAP9 Rho GTPase activating protein 9
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL13B ADP-ribosylation factor-like 13B
ARMCX3 armadillo repeat containing, X-linked 3
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
AURKB aurora kinase B
B9D2 B9 protein domain 2
BAIAP2 BAI1-associated protein 2
BAIAP2L1 BAI1-associated protein 2-like 1
BAIAP2L2 BAI1-associated protein 2-like 2
BASP1 brain abundant, membrane attached signal protein 1
BCAP31 B-cell receptor-associated protein 31
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
BLTP3B bridge-like lipid transfer protein family member 3B
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C1QBP complement component 1, q subcomponent binding protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPZB capping protein (actin filament) muscle Z-line, beta
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CCDC115 coiled-coil domain containing 115
CCDC187 coiled-coil domain containing 187
CCDC88A coiled-coil domain containing 88A
CCP110 centriolar coiled coil protein 110kDa
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC20 cell division cycle 20
CDC25C cell division cycle 25C
CDC37 cell division cycle 37
CDC42 cell division cycle 42
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDC42SE2 CDC42 small effector 2
CDCA8 cell division cycle associated 8
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENPA centromere protein A
CENPC centromere protein C
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPH centromere protein H
CENPI centromere protein I
CENPK centromere protein K
CENPL centromere protein L
CENPM centromere protein M
CENPN centromere protein N
CENPO centromere protein O
CENPP centromere protein P
CENPQ centromere protein Q
CENPS-CORT CENPS-CORT readthrough
CENPT centromere protein T
CENPU centromere protein U
CEP97 centrosomal protein 97kDa
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHN1 chimerin 1
CHN2 chimerin 2
CIT citron rho-interacting serine/threonine kinase
CKAP4 cytoskeleton-associated protein 4
CKAP5 cytoskeleton associated protein 5
CKB creatine kinase, brain
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLIP1 CAP-GLY domain containing linker protein 1
CLTC clathrin, heavy chain (Hc)
COPS2 COP9 signalosome subunit 2
COPS4 COP9 signalosome subunit 4
CPD carboxypeptidase D
CPNE8 copine VIII
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSK c-src tyrosine kinase
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CUL3 cullin 3
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAAM1 dishevelled associated activator of morphogenesis 1
DBN1 drebrin 1
DBT dihydrolipoamide branched chain transacylase E2
DDRGK1 DDRGK domain containing 1
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPDC1B DEP domain containing 1B
DIAPH1 diaphanous-related formin 1
DIAPH2 diaphanous-related formin 2
DIAPH3 diaphanous-related formin 3
DLC1 DLC1 Rho GTPase activating protein
DLG4 discs, large homolog 4 (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DNMBP dynamin binding protein
DOCK1 dedicator of cytokinesis 1
DOCK10 dedicator of cytokinesis 10
DOCK11 dedicator of cytokinesis 11
DOCK2 dedicator of cytokinesis 2
DOCK3 dedicator of cytokinesis 3
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
DOCK6 dedicator of cytokinesis 6
DOCK7 dedicator of cytokinesis 7
DOCK8 dedicator of cytokinesis 8
DOCK9 dedicator of cytokinesis 9
DSG1 desmoglein 1
DSG2 desmoglein 2
DSN1 DSN1, MIS12 kinetochore complex component
DSP desmoplakin
DST dystonin
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
ECT2 epithelial cell transforming 2
EFHD2 EF-hand domain family, member D2
ELMO2 engulfment and cell motility 2
EMC3 ER membrane protein complex subunit 3
EMD emerin
EPHA2 EPH receptor A2
EPSTI1 epithelial stromal interaction 1 (breast)
ERBIN erbb2 interacting protein
ERCC6L excision repair cross-complementation group 6-like
ESYT1 extended synaptotagmin-like protein 1
EVL Enah/Vasp-like
FAF2 Fas associated factor family member 2
FAM135A family with sequence similarity 135, member A
FAM13A family with sequence similarity 13, member A
FAM13B family with sequence similarity 13, member B
FAM169A family with sequence similarity 169, member A
FAM91A1 family with sequence similarity 91, member A1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FERMT2 fermitin family member 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGD5 FYVE, RhoGEF and PH domain containing 5
FILIP1 filamin A interacting protein 1
FLNA filamin A, alpha
FLOT1 flotillin 1
FLOT2 flotillin 2
FMNL1 formin-like 1
FMNL2 formin-like 2
FMNL3 formin-like 3
FNBP1 formin binding protein 1
FNBP1L formin binding protein 1-like
FRS2 fibroblast growth factor receptor substrate 2
FRS3 fibroblast growth factor receptor substrate 3
GARRE1 granule associated Rac and RHOG effector 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA1 gap junction protein, alpha 1, 43kDa
GMIP GEM interacting protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GOLGA3 golgin A3
GOLGA8R golgin A8 family, member R
GOPC golgi-associated PDZ and coiled-coil motif containing
GPS1 G protein pathway suppressor 1
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
H2AB1 H2A.B variant histone 1
H2AC14 H2A clustered histone 14
H2AC18 H2A clustered histone 18
H2AC20 H2A clustered histone 20
H2AC4 H2A clustered histone 4
H2AC6 H2A clustered histone 6
H2AC7 H2A clustered histone 7
H2AJ H2A.J histone
H2AX H2A.X variant histone
H2AZ2 H2A.Z variant histone 2
H2BC1 H2B clustered histone 1
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC13 H2B clustered histone 13
H2BC14 H2B clustered histone 14
H2BC15 H2B clustered histone 15
H2BC17 H2B clustered histone 17
H2BC21 H2B clustered histone 21
H2BC26 H2B clustered histone 26
H2BC3 H2B clustered histone 3
H2BC4 H2B clustered histone 4
H2BC5 H2B clustered histone 5
H2BC9 H2B clustered histone 9
H3-3A H3.3 histone A
H3C15 H3 clustered histone 15
H3C8 H3 clustered histone 8
H4C1 H4 clustered histone 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HINT2 histidine triad nucleotide binding protein 2
HMOX2 heme oxygenase 2
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPE1 heat shock 10kDa protein 1
IL32 interleukin 32
INCENP inner centromere protein antigens 135/155kDa
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
ITSN1 intersectin 1 (SH3 domain protein)
ITSN2 intersectin 2
JAG1 jagged 1
JUP junction plakoglobin
KALRN kalirin, RhoGEF kinase
KCTD13 potassium channel tetramerization domain containing 13
KCTD3 potassium channel tetramerization domain containing 3
KDM1A lysine (K)-specific demethylase 1A
KDM4C lysine (K)-specific demethylase 4C
KIDINS220 kinase D-interacting substrate, 220kDa
KIF14 kinesin family member 14
KIF18A kinesin family member 18A
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KIF5A kinesin family member 5A
KIF5B kinesin family member 5B
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLC3 kinesin light chain 3
KLC4 kinesin light chain 4
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KNL1 kinetochore scaffold 1
KNTC1 kinetochore associated 1
KTN1 kinectin 1 (kinesin receptor)
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LBR lamin B receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LEMD3 LEM domain containing 3
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LIN7B lin-7 homolog B (C. elegans)
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LRRC1 leucine rich repeat containing 1
MACO1 macoilin 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MCAM melanoma cell adhesion molecule
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MEN1 multiple endocrine neoplasia I
MIS12 MIS12 kinetochore complex component
MOSPD2 motile sperm domain containing 2
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MRTFA myocardin related transcription factor A
MSI2 musashi RNA-binding protein 2
MTMR1 myotubularin related protein 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTX1 metaxin 1
MUC13 mucin 13, cell surface associated
MYH10 myosin, heavy chain 10, non-muscle
MYH11 myosin, heavy chain 11, smooth muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12B myosin, light chain 12B, regulatory
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
MYO6 myosin VI
MYO9A myosin IXA
MYO9B myosin IXB
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NCKIPSD NCK interacting protein with SH3 domain
NCOA2 nuclear receptor coactivator 2
NDC80 NDC80 kinetochore complex component
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NET1 neuroepithelial cell transforming 1
NF2 neurofibromin 2 (merlin)
NGEF neuronal guanine nucleotide exchange factor
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NIPSNAP2 nipsnap homolog 2
NISCH nischarin
NOX1 NADPH oxidase 1
NOX3 NADPH oxidase 3
NOXA1 NADPH oxidase activator 1
NOXO1 NADPH oxidase organizer 1
NSFL1C NSFL1 (p97) cofactor (p47)
NSL1 NSL1, MIS12 kinetochore complex component
NUDC nudC nuclear distribution protein
NUF2 NUF2, NDC80 kinetochore complex component
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
NUP160 nucleoporin 160kDa
NUP37 nucleoporin 37kDa
NUP43 nucleoporin 43kDa
NUP85 nucleoporin 85kDa
NUP98 nucleoporin 98kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCRL oculocerebrorenal syndrome of Lowe
OPHN1 oligophrenin 1
OSBPL11 oxysterol binding protein-like 11
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAK5 p21 (RAC1) activated kinase 5
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARD6A par-6 family cell polarity regulator alpha
PARD6B par-6 family cell polarity regulator beta
PCDH7 protocadherin 7
PDE5A phosphodiesterase 5A, cGMP-specific
PDPK1 3-phosphoinositide dependent protein kinase 1
PEAK1 pseudopodium-enriched atypical kinase 1
PFN1 profilin 1
PFN2 profilin 2
PGRMC2 progesterone receptor membrane component 2
PHIP pleckstrin homology domain interacting protein
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKN1 protein kinase N1
PKN2 protein kinase N2
PKN3 protein kinase N3
PKP4 plakophilin 4
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLK1 polo-like kinase 1
PLXNA1 plexin A1
PLXNB1 plexin B1
PLXND1 plexin D1
PMF1 polyamine-modulated factor 1
POTEE POTE ankyrin domain family, member E
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRAG1 PEAK1 related, kinase-activating pseudokinase 1
PRC1 protein regulator of cytokinesis 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RACGAP1 Rac GTPase activating protein 1
RALBP1 ralA binding protein 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASAL2 RAS protein activator like 2
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RBBP6 retinoblastoma binding protein 6
RBMX RNA binding motif protein, X-linked
RCC2 regulator of chromosome condensation 2
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOF ras homolog family member F (in filopodia)
RHOG ras homolog family member G
RHOH ras homolog family member H
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RHOU ras homolog family member U
RHOV ras homolog family member V
RHPN1 rhophilin, Rho GTPase binding protein 1
RHPN2 rhophilin, Rho GTPase binding protein 2
RND1 Rho family GTPase 1
RND2 Rho family GTPase 2
RND3 Rho family GTPase 3
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROPN1 rhophilin associated tail protein 1
RPS27 ribosomal protein S27
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RTKN rhotekin
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SACK1B scaffolding CK1 anchoring protein B
SAMM50 SAMM50 sorting and assembly machinery component
SCAI suppressor of cancer cell invasion
SCFD1 sec1 family domain containing 1
SCRIB scribbled planar cell polarity protein
SEC13 SEC13 homolog (S. cerevisiae)
SEH1L SEH1-like (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SENP1 SUMO1/sentrin specific peptidase 1
SFN stratifin
SGO1 shugoshin 1
SGO2 shugoshin 2
SH3BP1 SH3-domain binding protein 1
SH3PXD2A SH3 and PX domains 2A
SH3RF1 SH3 domain containing ring finger 1
SHKBP1 SH3KBP1 binding protein 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SKA1 spindle and kinetochore associated complex subunit 1
SKA2 spindle and kinetochore associated complex subunit 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLITRK3 SLIT and NTRK-like family, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SLK STE20-like kinase
SNAP23 synaptosomal-associated protein, 23kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SOWAHC sosondowah ankyrin repeat domain family member C
SPATA13 spermatogenesis associated 13
SPC24 SPC24, NDC80 kinetochore complex component
SPC25 SPC25, NDC80 kinetochore complex component
SPDL1 spindle apparatus coiled-coil protein 1
SPEN spen family transcriptional repressor
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRRM1 serine/arginine repetitive matrix 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
STIP1 stress-induced phosphoprotein 1
STK10 serine/threonine kinase 10
STK38 serine/threonine kinase 38
STMN2 stathmin 2
STOM stomatin
STX5 syntaxin 5
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAGAP T-cell activation RhoGTPase activating protein
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TEX2 testis expressed 2
TFRC transferrin receptor
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TJP2 tight junction protein 2
TMEM59 transmembrane protein 59
TMEM87A transmembrane protein 87A
TMOD3 tropomodulin 3 (ubiquitous)
TMPO thymopoietin
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TOR1AIP1 torsin A interacting protein 1
TPM3 tropomyosin 3
TPM4 tropomyosin 4
TRA2B transformer 2 beta homolog (Drosophila)
TRIO trio Rho guanine nucleotide exchange factor
TRIP10 thyroid hormone receptor interactor 10
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3E tubulin, alpha 3e
TUBA4A tubulin, alpha 4a
TUBA4B tubulin, alpha 4b
TUBA8 tubulin, alpha 8
TUBAL3 tubulin, alpha-like 3
TUBB1 tubulin, beta 1 class VI
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TUBB8B tubulin beta 8B
TWF1 twinfilin actin binding protein 1
TXNL1 thioredoxin-like 1
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBXN11 UBX domain protein 11
USP9X ubiquitin specific peptidase 9, X-linked
VAMP3 vesicle-associated membrane protein 3
VANGL1 VANGL planar cell polarity protein 1
VANGL2 VANGL planar cell polarity protein 2
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCP valosin containing protein
VIM vimentin
VRK2 vaccinia related kinase 2
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WASL Wiskott-Aldrich syndrome-like
WDR11 WD repeat domain 11
WDR6 WD repeat domain 6
WDR81 WD repeat domain 81
WDR91 WD repeat domain 91
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XPO1 exportin 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZNF512B zinc finger protein 512B
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein