Signaling by SCF-KIT Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-1433557
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Genes

43 proteins participating in the Signaling by SCF-KIT pathway from the Reactome Pathways 2024 dataset.

Symbol Name
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHEK1 checkpoint kinase 1
CMA1 chymase 1, mast cell
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB10 growth factor receptor-bound protein 10
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
HRAS Harvey rat sarcoma viral oncogene homolog
JAK2 Janus kinase 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KRAS Kirsten rat sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LYN LYN proto-oncogene, Src family tyrosine kinase
MMP9 matrix metallopeptidase 9
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PRKCA protein kinase C, alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRU protein tyrosine phosphatase, receptor type, U
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SH2B2 SH2B adaptor protein 2
SH2B3 SH2B adaptor protein 3
SOCS1 suppressor of cytokine signaling 1
SOCS6 suppressor of cytokine signaling 6
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TEC tec protein tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor
YES1 YES proto-oncogene 1, Src family tyrosine kinase