Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-2404192
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Genes

54 proteins participating in the Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT2 v-akt murine thymoma viral oncogene homolog 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FRS2 fibroblast growth factor receptor substrate 2
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
KL klotho
KLB klotho beta
KRAS Kirsten rat sarcoma viral oncogene homolog
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
THEM4 thioesterase superfamily member 4
TLR9 toll-like receptor 9
TRIB3 tribbles pseudokinase 3