Signaling events mediated by Stem cell factor receptor (c-Kit) Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/c6b6861c-6195-11e5-8ac5-06603eb7f303
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Genes

52 proteins participating in the Signaling events mediated by Stem cell factor receptor (c-Kit) pathway from the PID Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CREBBP CREB binding protein
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EPO erythropoietin
EPOR erythropoietin receptor
FER fer (fps/fes related) tyrosine kinase
FOXO3 forkhead box O3
GAB1 GRB2-associated binding protein 1
GRAP2 GRB2-related adaptor protein 2
GRB10 growth factor receptor-bound protein 10
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
HRAS Harvey rat sarcoma viral oncogene homolog
JAK2 Janus kinase 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MATK megakaryocyte-associated tyrosine kinase
MITF microphthalmia-associated transcription factor
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRO protein tyrosine phosphatase, receptor type, O
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SH2B2 SH2B adaptor protein 2
SH2B3 SH2B adaptor protein 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
STAP1 signal transducing adaptor family member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
TEC tec protein tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor