Signalling to ERKs Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-187687
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Genes

34 proteins participating in the Signalling to ERKs pathway from the Reactome Pathways 2024 dataset.

Symbol Name
BRAF B-Raf proto-oncogene, serine/threonine kinase
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
FRS2 fibroblast growth factor receptor substrate 2
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
KIDINS220 kinase D-interacting substrate, 220kDa
KRAS Kirsten rat sarcoma viral oncogene homolog
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NGF nerve growth factor (beta polypeptide)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RALGDS ral guanine nucleotide dissociation stimulator
RAP1A RAP1A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta