| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sildenafil perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sildenafil_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.146204 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.120548 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.12041 |
| ANXA2 | annexin A2 | 0.111285 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.109454 |
| LMO7 | LIM domain 7 | 0.108475 |
| EXT1 | exostosin glycosyltransferase 1 | 0.106224 |
| RNF213 | ring finger protein 213 | 0.102797 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.102594 |
| EZR | ezrin | 0.094557 |
| VCL | vinculin | 0.0913799 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0906279 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0849504 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0834668 |
| PHF3 | PHD finger protein 3 | 0.0823434 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0816262 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0790709 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0762303 |
| INTS6 | integrator complex subunit 6 | 0.073505 |
| PRKCA | protein kinase C, alpha | 0.0713555 |
| MX1 | MX dynamin-like GTPase 1 | 0.0701299 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0648333 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0631288 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0619758 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.060894 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0599369 |
| PLSCR2 | phospholipid scramblase 2 | 0.0585702 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0583408 |
| RAD51B | RAD51 paralog B | 0.0556183 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0554117 |
| MCL1 | myeloid cell leukemia 1 | 0.0552756 |
| SP100 | SP100 nuclear antigen | 0.0541857 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.054088 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0530337 |
| EFNB2 | ephrin-B2 | 0.0528426 |
| RIGI | RNA sensor RIG-I | 0.0518297 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0517246 |
| VMP1 | vacuole membrane protein 1 | 0.0509969 |
| SMAD3 | SMAD family member 3 | 0.0508916 |
| MAP7 | microtubule-associated protein 7 | 0.0506629 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0492015 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0462602 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0448035 |
| PLSCR1 | phospholipid scramblase 1 | 0.044632 |
| SDC4 | syndecan 4 | 0.0431199 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0428931 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0426734 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0424494 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0417576 |
| AREG | amphiregulin | 0.0415221 |
| AHI1 | Abelson helper integration site 1 | 0.0413538 |
| MSI2 | musashi RNA-binding protein 2 | 0.0413214 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0412767 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0411635 |
| ASPH | aspartate beta-hydroxylase | 0.0411515 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0405689 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0405586 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0401576 |
| ATXN1 | ataxin 1 | 0.0400413 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0400254 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0398524 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.039276 |
| TJP1 | tight junction protein 1 | 0.039162 |
| IRF1 | interferon regulatory factor 1 | 0.0390949 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0389497 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0382322 |
| RBM39 | RNA binding motif protein 39 | 0.0380835 |
| ITGA6 | integrin, alpha 6 | 0.0379256 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0372098 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0370544 |
| IRS2 | insulin receptor substrate 2 | 0.0368935 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0366601 |
| EXOC4 | exocyst complex component 4 | 0.0366107 |
| TUFT1 | tuftelin 1 | 0.0360365 |
| ADAR | adenosine deaminase, RNA-specific | 0.0359967 |
| STK24 | serine/threonine kinase 24 | 0.0358533 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0355324 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0354693 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0348765 |
| MYO1E | myosin IE | 0.0347622 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0345703 |
| IFNGR1 | interferon gamma receptor 1 | 0.0345165 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0344735 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0342468 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0339584 |
| MX2 | MX dynamin-like GTPase 2 | 0.0331844 |
| HDAC4 | histone deacetylase 4 | 0.0331727 |
| NPSR1 | neuropeptide S receptor 1 | 0.0330186 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0329457 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0327091 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0323797 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0323481 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0322044 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0321276 |
| SQSTM1 | sequestosome 1 | 0.0319757 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0318081 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0315967 |
| CCNL1 | cyclin L1 | 0.0314957 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0314739 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0314055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.0703661 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0588695 |
| NDRG1 | N-myc downstream regulated 1 | -0.0533831 |
| RPS6 | ribosomal protein S6 | -0.0446276 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0377506 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324354 |
| RPL35A | ribosomal protein L35a | -0.0308421 |
| RPL12 | ribosomal protein L12 | -0.0293216 |
| FTL | ferritin, light polypeptide | -0.0285564 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0274312 |
| TMSB10 | thymosin beta 10 | -0.0267437 |
| RPS19 | ribosomal protein S19 | -0.0261478 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0240512 |
| RPL34 | ribosomal protein L34 | -0.0237547 |
| HLA-B | major histocompatibility complex, class I, B | -0.0229449 |
| RPS27 | ribosomal protein S27 | -0.0223963 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0223788 |
| RPLP1 | ribosomal protein, large, P1 | -0.0220848 |
| RPL37 | ribosomal protein L37 | -0.0220221 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0219068 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.021073 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0209315 |
| RPS8 | ribosomal protein S8 | -0.0204826 |
| WDR45B | WD repeat domain 45B | -0.020179 |
| RNF43 | ring finger protein 43 | -0.0200294 |
| AFTPH | aftiphilin | -0.0193112 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0188538 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0188409 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0188382 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.018831 |
| RPS11 | ribosomal protein S11 | -0.0182678 |
| RNF149 | ring finger protein 149 | -0.0182134 |
| GNAS | GNAS complex locus | -0.0181937 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0178448 |
| COPA | coatomer protein complex, subunit alpha | -0.0178146 |
| CSTB | cystatin B (stefin B) | -0.0177254 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0176808 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0175603 |
| RPL23 | ribosomal protein L23 | -0.0175046 |
| RPL31 | ribosomal protein L31 | -0.0172448 |
| WASF2 | WAS protein family, member 2 | -0.0170782 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0169888 |
| RPL32 | ribosomal protein L32 | -0.0168371 |
| ATF4 | activating transcription factor 4 | -0.0161372 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.015879 |
| RPL37A | ribosomal protein L37a | -0.0158665 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0155312 |
| MT2A | metallothionein 2A | -0.015199 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0151845 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0151499 |
| RPLP2 | ribosomal protein, large, P2 | -0.0150198 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0148868 |
| RPL19 | ribosomal protein L19 | -0.0146971 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.014674 |
| MT1X | metallothionein 1X | -0.0146452 |
| RPL36 | ribosomal protein L36 | -0.0145986 |
| RPL30 | ribosomal protein L30 | -0.0141798 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0140522 |
| FAF2 | Fas associated factor family member 2 | -0.0138068 |
| RPL7 | ribosomal protein L7 | -0.0134514 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0133433 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0132714 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0132298 |
| RPL18 | ribosomal protein L18 | -0.0131833 |
| DUSP6 | dual specificity phosphatase 6 | -0.0131179 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0130532 |
| TMEM59 | transmembrane protein 59 | -0.0126717 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0125862 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0125614 |
| WBP2 | WW domain binding protein 2 | -0.0125109 |
| RPS12 | ribosomal protein S12 | -0.0123108 |
| RPS14 | ribosomal protein S14 | -0.0123077 |
| SYF2 | SYF2 pre-mRNA-splicing factor | -0.012169 |
| PURA | purine-rich element binding protein A | -0.0121237 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0120879 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0120861 |
| RPL11 | ribosomal protein L11 | -0.0119568 |
| KRT19 | keratin 19, type I | -0.0117548 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0117498 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0117314 |
| FBXO9 | F-box protein 9 | -0.0116811 |
| S100A9 | S100 calcium binding protein A9 | -0.0116564 |
| BMP4 | bone morphogenetic protein 4 | -0.0116211 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0115585 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0115385 |
| RPL36A | ribosomal protein L36a | -0.011532 |
| TBCA | tubulin folding cofactor A | -0.0114887 |
| S100P | S100 calcium binding protein P | -0.0114871 |
| RPL26 | ribosomal protein L26 | -0.0112924 |
| MTDH | metadherin | -0.011274 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0112606 |
| KCNK6 | potassium channel, two pore domain subfamily K, member 6 | -0.0112601 |
| FOXO3 | forkhead box O3 | -0.011208 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0111254 |
| RTN4 | reticulon 4 | -0.0111228 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0110996 |
| PER3 | period circadian clock 3 | -0.0110941 |
| USP3 | ubiquitin specific peptidase 3 | -0.0110866 |
| MKI67 | marker of proliferation Ki-67 | -0.0110751 |
| CST3 | cystatin C | -0.010951 |
