| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sildenafil perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sildenafil_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2A | myocyte enhancer factor 2A | 0.0932414 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0853097 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0794598 |
| NDRG1 | N-myc downstream regulated 1 | 0.072085 |
| FLNB | filamin B, beta | 0.0692798 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0599818 |
| CLU | clusterin | 0.0529326 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0506093 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.050119 |
| GOLGA4 | golgin A4 | 0.049893 |
| OGA | O-GlcNAcase | 0.0463205 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0450155 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0442657 |
| PGK1 | phosphoglycerate kinase 1 | 0.0406626 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0402243 |
| SUCO | SUN domain containing ossification factor | 0.0396492 |
| RBM39 | RNA binding motif protein 39 | 0.0385557 |
| ARRDC3 | arrestin domain containing 3 | 0.0380338 |
| EZR | ezrin | 0.0356815 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0348546 |
| SQLE | squalene epoxidase | 0.0343549 |
| KRT17 | keratin 17, type I | 0.0341079 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0335367 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0326182 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0326017 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0319821 |
| COPA | coatomer protein complex, subunit alpha | 0.0318657 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0313186 |
| BCL2L1 | BCL2-like 1 | 0.0310048 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0306424 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0301739 |
| HELZ | helicase with zinc finger | 0.0296915 |
| NUP58 | nucleoporin 58 | 0.0296691 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.02928 |
| DSTN | destrin (actin depolymerizing factor) | 0.0291377 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0290708 |
| RNF145 | ring finger protein 145 | 0.0290164 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0282026 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0281143 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0280481 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0277354 |
| SPAG9 | sperm associated antigen 9 | 0.0275694 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0274538 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0268281 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0265603 |
| TFG | TRK-fused gene | 0.0264164 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0261005 |
| ZNF292 | zinc finger protein 292 | 0.0260487 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0258138 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0252926 |
| SLK | STE20-like kinase | 0.0251478 |
| NBAS | neuroblastoma amplified sequence | 0.0248478 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0244732 |
| GLYAT | glycine-N-acyltransferase | 0.0244071 |
| ANXA2 | annexin A2 | 0.02417 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.024144 |
| GATA6 | GATA binding protein 6 | 0.0239829 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0239142 |
| SRP54 | signal recognition particle 54kDa | 0.0238663 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0236937 |
| EMP1 | epithelial membrane protein 1 | 0.0236497 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0236466 |
| RTN4 | reticulon 4 | 0.0234581 |
| COG5 | component of oligomeric golgi complex 5 | 0.0233105 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0230529 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0230374 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0228019 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0226803 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0225445 |
| ARF4 | ADP-ribosylation factor 4 | 0.0225303 |
| USP3 | ubiquitin specific peptidase 3 | 0.0225129 |
| CDC73 | cell division cycle 73 | 0.0224852 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0224381 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0220103 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.022007 |
| FOXO1 | forkhead box O1 | 0.0219277 |
| CUL4B | cullin 4B | 0.0218059 |
| ANXA11 | annexin A11 | 0.0217996 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.021664 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0215887 |
| CALU | calumenin | 0.0214735 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0213931 |
| ANLN | anillin, actin binding protein | 0.0213744 |
| PLEC | plectin | 0.0213273 |
| ITGA6 | integrin, alpha 6 | 0.0212646 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0212485 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.021144 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0211317 |
| TMEM39A | transmembrane protein 39A | 0.0209829 |
| RNF19B | ring finger protein 19B | 0.0208959 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0208881 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.02075 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.020547 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0204862 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0204127 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0203706 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0202829 |
| SERINC3 | serine incorporator 3 | 0.0202599 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0201197 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.020082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.38794 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.210789 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.191122 |
| DPYD | dihydropyrimidine dehydrogenase | -0.115148 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.10909 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.109056 |
| SLC35F3 | solute carrier family 35, member F3 | -0.106875 |
| LMO7 | LIM domain 7 | -0.101984 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0993801 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0930987 |
| INTS6 | integrator complex subunit 6 | -0.0847713 |
| HMGA2 | high mobility group AT-hook 2 | -0.080026 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0787321 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0727332 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0705609 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0672252 |
| RASAL2 | RAS protein activator like 2 | -0.0667525 |
| MTSS1 | metastasis suppressor 1 | -0.0662817 |
| RIGI | RNA sensor RIG-I | -0.0662125 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0660186 |
| AHNAK | AHNAK nucleoprotein | -0.0626894 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0599762 |
| RAD51B | RAD51 paralog B | -0.0588901 |
| PRSS23 | protease, serine, 23 | -0.0583615 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0574936 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0570746 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0559007 |
| SULF1 | sulfatase 1 | -0.0552993 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0550371 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.053858 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0517978 |
| SULF2 | sulfatase 2 | -0.0509529 |
| MECOM | MDS1 and EVI1 complex locus | -0.0502764 |
| CDK6 | cyclin-dependent kinase 6 | -0.0485236 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0445043 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0435099 |
| TMSB4X | thymosin beta 4, X-linked | -0.0428265 |
| RPS21 | ribosomal protein S21 | -0.0424758 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0418773 |
| TMSB10 | thymosin beta 10 | -0.0410994 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0406754 |
| PALLD | palladin, cytoskeletal associated protein | -0.0406153 |
| LAMC2 | laminin, gamma 2 | -0.040226 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0401905 |
| RAI14 | retinoic acid induced 14 | -0.0399709 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0397673 |
| UTRN | utrophin | -0.0396499 |
| EFNA5 | ephrin-A5 | -0.0394272 |
| MTAP | methylthioadenosine phosphorylase | -0.0393229 |
| RPS8 | ribosomal protein S8 | -0.0392924 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387835 |
| RPLP2 | ribosomal protein, large, P2 | -0.0376121 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0370784 |
| RPS6 | ribosomal protein S6 | -0.0368457 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0367343 |
| SMYD3 | SET and MYND domain containing 3 | -0.0365551 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.036495 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0361041 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0359481 |
| FN1 | fibronectin 1 | -0.0357431 |
| ACTG1 | actin gamma 1 | -0.0350543 |
| MT2A | metallothionein 2A | -0.0344321 |
| KIAA1671 | KIAA1671 | -0.0341566 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.033657 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0319111 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0316968 |
| CRACDL | CRACD like | -0.0313529 |
| EXOC4 | exocyst complex component 4 | -0.0310113 |
| ASPH | aspartate beta-hydroxylase | -0.030558 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0304108 |
| DGKH | diacylglycerol kinase, eta | -0.0301586 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.030124 |
| RPS3 | ribosomal protein S3 | -0.029939 |
| PLS3 | plastin 3 | -0.0296282 |
| RPS19 | ribosomal protein S19 | -0.0294347 |
| ACTN4 | actinin, alpha 4 | -0.0291158 |
| PLXNA2 | plexin A2 | -0.0287786 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0285961 |
| TENM4 | teneurin transmembrane protein 4 | -0.0285293 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0284239 |
| HDAC9 | histone deacetylase 9 | -0.0283047 |
| CUX1 | cut-like homeobox 1 | -0.0281333 |
| RNF217 | ring finger protein 217 | -0.0280719 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.02793 |
| FRMD4B | FERM domain containing 4B | -0.0275855 |
| RPS24 | ribosomal protein S24 | -0.0273147 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0272683 |
| RPL37 | ribosomal protein L37 | -0.0272048 |
| THBD | thrombomodulin | -0.0271433 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0270495 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0268391 |
| RPL11 | ribosomal protein L11 | -0.0268027 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0267556 |
| RPL34 | ribosomal protein L34 | -0.0265377 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259524 |
| AMOTL1 | angiomotin like 1 | -0.0259156 |
| TNS3 | tensin 3 | -0.0257654 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0256341 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0255926 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0253284 |
