| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Silodosin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Silodosin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.040563 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0393105 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0290169 |
| PHF3 | PHD finger protein 3 | 0.0281535 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0274084 |
| RPL35A | ribosomal protein L35a | 0.0257643 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0253811 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0253167 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0250258 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0248994 |
| PTCHD4 | patched domain containing 4 | 0.0244585 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0239581 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0238689 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0237998 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0234149 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230148 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0229708 |
| CALD1 | caldesmon 1 | 0.0226709 |
| EHBP1 | EH domain binding protein 1 | 0.0224006 |
| RDX | radixin | 0.0219559 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0217262 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0216628 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0213972 |
| CENPF | centromere protein F, 350/400kDa | 0.0209076 |
| ZNF644 | zinc finger protein 644 | 0.0207871 |
| RPS2 | ribosomal protein S2 | 0.0206633 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0206009 |
| RPL37A | ribosomal protein L37a | 0.020112 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196677 |
| DOK6 | docking protein 6 | 0.019235 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0189476 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0181869 |
| RPS12 | ribosomal protein S12 | 0.0179074 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0174919 |
| CPE | carboxypeptidase E | 0.017033 |
| PLIN2 | perilipin 2 | 0.016936 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.016628 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0164392 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0164375 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0163992 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0160091 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0159349 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0158954 |
| CP | ceruloplasmin (ferroxidase) | 0.0158173 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0157151 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0157138 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0157034 |
| GOLM2 | golgi membrane protein 2 | 0.0155848 |
| RPS7 | ribosomal protein S7 | 0.0154881 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0152381 |
| AAK1 | AP2 associated kinase 1 | 0.0152323 |
| HLF | hepatic leukemia factor | 0.0152302 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0151219 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0150424 |
| STK39 | serine threonine kinase 39 | 0.0145965 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.0143039 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0142803 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.0142213 |
| CRY1 | cryptochrome circadian clock 1 | 0.0141033 |
| DSPP | dentin sialophosphoprotein | 0.0140236 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0138735 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.0137088 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.013385 |
| GNAS | GNAS complex locus | 0.0133772 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0133145 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0132197 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0132177 |
| EPCAM | epithelial cell adhesion molecule | 0.0132117 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0130861 |
| SIK3 | SIK family kinase 3 | 0.0129894 |
| USP8 | ubiquitin specific peptidase 8 | 0.0128338 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0126874 |
| PKP4 | plakophilin 4 | 0.0125623 |
| CCDC146 | coiled-coil domain containing 146 | 0.0125596 |
| MALT1 | MALT1 paracaspase | 0.0122655 |
| CPQ | carboxypeptidase Q | 0.0122234 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0120534 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0120532 |
| N4BP1 | NEDD4 binding protein 1 | 0.0120126 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0119966 |
| TLK1 | tousled-like kinase 1 | 0.0119521 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0119076 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0119029 |
| PLSCR1 | phospholipid scramblase 1 | 0.0117634 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0117041 |
| SMAP1 | small ArfGAP 1 | 0.0116128 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0115553 |
| GPATCH8 | G patch domain containing 8 | 0.0115529 |
| FOSL2 | FOS-like antigen 2 | 0.0115304 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0115061 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0114876 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0114651 |
| RBBP4 | retinoblastoma binding protein 4 | 0.0114388 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0111932 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0110187 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0110181 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0109874 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0109824 |
| TRIM56 | tripartite motif containing 56 | 0.0108717 |
| CD109 | CD109 molecule | 0.0107771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.259234 |
| APOB | apolipoprotein B | -0.187029 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165608 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.139817 |
| UBC | ubiquitin C | -0.139624 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.118301 |
| ENO1 | enolase 1, (alpha) | -0.11579 |
| RPS27A | ribosomal protein S27a | -0.103239 |
| FN1 | fibronectin 1 | -0.0990853 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0957687 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0942706 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0902191 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0844469 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0792176 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0766255 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0711215 |
| KRT8 | keratin 8, type II | -0.0682304 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0676256 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0626428 |
| JUN | jun proto-oncogene | -0.0590041 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0586634 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0569764 |
| RPL23 | ribosomal protein L23 | -0.0537458 |
| SVIL | supervillin | -0.0518216 |
| AHNAK | AHNAK nucleoprotein | -0.0517047 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0511136 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0482446 |
| FLNB | filamin B, beta | -0.0481157 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0459148 |
| APOE | apolipoprotein E | -0.0447934 |
| SDC4 | syndecan 4 | -0.0446124 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0443996 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0441788 |
| ASPH | aspartate beta-hydroxylase | -0.042763 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0417704 |
| RPS24 | ribosomal protein S24 | -0.0399803 |
| ACTG1 | actin gamma 1 | -0.0384644 |
| TRIM26 | tripartite motif containing 26 | -0.0379554 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0378864 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.036492 |
| NDRG1 | N-myc downstream regulated 1 | -0.0361696 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0360649 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0354921 |
| PKM | pyruvate kinase, muscle | -0.0354004 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0353879 |
| PCBP2 | poly(rC) binding protein 2 | -0.0352719 |
| CALR | calreticulin | -0.0352064 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0345647 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.03453 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0344816 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0342976 |
| LDHA | lactate dehydrogenase A | -0.0337616 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0336915 |
| SMAD3 | SMAD family member 3 | -0.0334294 |
| RRBP1 | ribosome binding protein 1 | -0.032871 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.032545 |
| HDLBP | high density lipoprotein binding protein | -0.0324341 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0321765 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0320892 |
| TMSB10 | thymosin beta 10 | -0.0317491 |
| MRTFA | myocardin related transcription factor A | -0.0316709 |
| PARD3 | par-3 family cell polarity regulator | -0.0315531 |
| GLG1 | golgi glycoprotein 1 | -0.0314427 |
| FRMD5 | FERM domain containing 5 | -0.030219 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0301347 |
| USP34 | ubiquitin specific peptidase 34 | -0.0298014 |
| RPL8 | ribosomal protein L8 | -0.0297206 |
| BCL2L1 | BCL2-like 1 | -0.029554 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295171 |
| MCL1 | myeloid cell leukemia 1 | -0.0294877 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0293606 |
| SPAG9 | sperm associated antigen 9 | -0.0290421 |
| ACTN4 | actinin, alpha 4 | -0.0286245 |
| ANO6 | anoctamin 6 | -0.028229 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0278406 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0276578 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0275 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0273112 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0272535 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0272107 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0266721 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0262388 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0261213 |
| TOP1 | topoisomerase (DNA) I | -0.0260911 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0260255 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0258137 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0257256 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0254377 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0250949 |
| PTMA | prothymosin, alpha | -0.0248555 |
| FUS | FUS RNA binding protein | -0.024533 |
| RPL5 | ribosomal protein L5 | -0.0244151 |
| RPL34 | ribosomal protein L34 | -0.024285 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0241761 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0241325 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240977 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.023948 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0236822 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0234055 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0233131 |
