| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Silodosin perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Silodosin_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0683012 |
| HYOU1 | hypoxia up-regulated 1 | 0.0678617 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0618448 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0616562 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0611692 |
| GOLGA4 | golgin A4 | 0.0586853 |
| TES | testin LIM domain protein | 0.0562504 |
| PCBP2 | poly(rC) binding protein 2 | 0.0530267 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0499085 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0456036 |
| TMF1 | TATA element modulatory factor 1 | 0.0450265 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0443234 |
| VEGFA | vascular endothelial growth factor A | 0.0420581 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0415456 |
| POTEF | POTE ankyrin domain family, member F | 0.0408206 |
| SNX13 | sorting nexin 13 | 0.038942 |
| ANLN | anillin, actin binding protein | 0.0387708 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0383008 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.037344 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0334595 |
| DSTN | destrin (actin depolymerizing factor) | 0.0327943 |
| ARF4 | ADP-ribosylation factor 4 | 0.0314155 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.030838 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0303734 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0300889 |
| PTEN | phosphatase and tensin homolog | 0.0297312 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0295483 |
| FAM13A | family with sequence similarity 13, member A | 0.0288557 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0284544 |
| ATXN1 | ataxin 1 | 0.0284255 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0283169 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0281593 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271366 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0270512 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0266154 |
| RNF145 | ring finger protein 145 | 0.0260007 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.02579 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0256091 |
| CDK19 | cyclin-dependent kinase 19 | 0.0255936 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0253099 |
| CLTC | clathrin, heavy chain (Hc) | 0.0249819 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0248722 |
| TXNIP | thioredoxin interacting protein | 0.0245783 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0245132 |
| TPX2 | TPX2, microtubule-associated | 0.0244472 |
| ZNF148 | zinc finger protein 148 | 0.0244215 |
| RPS2 | ribosomal protein S2 | 0.024396 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0241489 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0240957 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0237013 |
| CLDN7 | claudin 7 | 0.0236586 |
| PCM1 | pericentriolar material 1 | 0.0235316 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0233509 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0233362 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0232956 |
| SRP54 | signal recognition particle 54kDa | 0.0231848 |
| XPO1 | exportin 1 | 0.0231789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.02302 |
| ENO1 | enolase 1, (alpha) | 0.022748 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0227321 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.022697 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0226027 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0225612 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0224517 |
| HKDC1 | hexokinase domain containing 1 | 0.0224326 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0223039 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0219095 |
| COG5 | component of oligomeric golgi complex 5 | 0.0216289 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0214567 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.021086 |
| BCL2L1 | BCL2-like 1 | 0.0209286 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0208933 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0208243 |
| KIF16B | kinesin family member 16B | 0.020455 |
| GOLGB1 | golgin B1 | 0.0203922 |
| TPM3 | tropomyosin 3 | 0.0203497 |
| ALPK1 | alpha-kinase 1 | 0.0203035 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0199052 |
| AUTS2 | autism susceptibility candidate 2 | 0.0198707 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0197638 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0197479 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0196947 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0196035 |
| PGM3 | phosphoglucomutase 3 | 0.0194534 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0193592 |
| NCKAP1 | NCK-associated protein 1 | 0.0193495 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0192691 |
| CCNY | cyclin Y | 0.0190608 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0188801 |
| DSPP | dentin sialophosphoprotein | 0.0188495 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0188094 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0187206 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0186687 |
| NBAS | neuroblastoma amplified sequence | 0.0186547 |
| PNN | pinin, desmosome associated protein | 0.0186097 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0185721 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0185075 |
| PGK1 | phosphoglycerate kinase 1 | 0.0184826 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.018471 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0184542 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.305864 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.145196 |
| LMO7 | LIM domain 7 | -0.112662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107473 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0902074 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0899567 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0806745 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0730488 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0711747 |
| EMP1 | epithelial membrane protein 1 | -0.0699479 |
| TMC5 | transmembrane channel-like 5 | -0.0690663 |
| TMSB10 | thymosin beta 10 | -0.0634113 |
| ANXA2 | annexin A2 | -0.0629282 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0604546 |
| S100A10 | S100 calcium binding protein A10 | -0.0596542 |
| KRT8 | keratin 8, type II | -0.055407 |
| FTL | ferritin, light polypeptide | -0.0465749 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0465741 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0463946 |
| MYO1E | myosin IE | -0.045883 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0457647 |
| ACTN4 | actinin, alpha 4 | -0.0452096 |
| WDR45B | WD repeat domain 45B | -0.0443852 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0435633 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0433784 |
| CD2AP | CD2-associated protein | -0.042963 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0425969 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.041151 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0406884 |
| RNF213 | ring finger protein 213 | -0.0403053 |
| RUNX1 | runt-related transcription factor 1 | -0.0400112 |
| MCU | mitochondrial calcium uniporter | -0.03976 |
| HLA-C | major histocompatibility complex, class I, C | -0.0391399 |
| HLA-E | major histocompatibility complex, class I, E | -0.0382576 |
| IER3 | immediate early response 3 | -0.0374111 |
| LAMA4 | laminin, alpha 4 | -0.0373471 |
| RPL35A | ribosomal protein L35a | -0.0372033 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0365992 |
| AGR2 | anterior gradient 2 | -0.03604 |
| B2M | beta-2-microglobulin | -0.0359102 |
| ACTG1 | actin gamma 1 | -0.0358385 |
| PTMA | prothymosin, alpha | -0.0353362 |
| CUX1 | cut-like homeobox 1 | -0.0348737 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0346509 |
| EPCAM | epithelial cell adhesion molecule | -0.0345121 |
| RRBP1 | ribosome binding protein 1 | -0.0342939 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0333525 |
| RPS25 | ribosomal protein S25 | -0.0332082 |
| HLA-A | major histocompatibility complex, class I, A | -0.0328062 |
| SULF2 | sulfatase 2 | -0.032463 |
| KLF6 | Kruppel-like factor 6 | -0.0320516 |
| XAF1 | XIAP associated factor 1 | -0.0315716 |
| RPS24 | ribosomal protein S24 | -0.0314953 |
| TJP1 | tight junction protein 1 | -0.0310666 |
| UBB | ubiquitin B | -0.0305097 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0302161 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0302061 |
| H1-0 | H1.0 linker histone | -0.0300375 |
| FRMD5 | FERM domain containing 5 | -0.0299789 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0298199 |
| CDK6 | cyclin-dependent kinase 6 | -0.0296481 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0293384 |
| RPL23 | ribosomal protein L23 | -0.0293308 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0292541 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0290316 |
| GNAS | GNAS complex locus | -0.0289737 |
| SHROOM3 | shroom family member 3 | -0.0279621 |
| S100A11 | S100 calcium binding protein A11 | -0.0278803 |
| RPL36A | ribosomal protein L36a | -0.0273347 |
| NPSR1 | neuropeptide S receptor 1 | -0.0272739 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.026995 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0269648 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0269404 |
| FUS | FUS RNA binding protein | -0.0268329 |
| SP100 | SP100 nuclear antigen | -0.0264929 |
| RPS6 | ribosomal protein S6 | -0.0264514 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0262485 |
| RPL34 | ribosomal protein L34 | -0.0262269 |
| MUC13 | mucin 13, cell surface associated | -0.0261874 |
| RPL12 | ribosomal protein L12 | -0.0260239 |
| POF1B | premature ovarian failure, 1B | -0.025832 |
| RAB7A | RAB7A, member RAS oncogene family | -0.025773 |
| RPL8 | ribosomal protein L8 | -0.0255863 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254547 |
| SIK3 | SIK family kinase 3 | -0.0252096 |
| GPX2 | glutathione peroxidase 2 | -0.025187 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0251855 |
| ATF5 | activating transcription factor 5 | -0.0251778 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0250943 |
| GPHN | gephyrin | -0.024892 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0247157 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0246663 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0246001 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0243473 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0242649 |
| HMGB1 | high mobility group box 1 | -0.0242168 |
| RPL19 | ribosomal protein L19 | -0.0238559 |
| RPS27A | ribosomal protein S27a | -0.0232981 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.022821 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0225437 |
