| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Silodosin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Silodosin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.17512 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.142621 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0927446 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0903151 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0810871 |
| FAM13A | family with sequence similarity 13, member A | 0.0750792 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0724642 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0717483 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0698863 |
| ZNF292 | zinc finger protein 292 | 0.0655219 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0653822 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0620027 |
| MEF2A | myocyte enhancer factor 2A | 0.0564229 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0563456 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0532766 |
| LDHA | lactate dehydrogenase A | 0.0522492 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0522137 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0519993 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0516422 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0515179 |
| CANX | calnexin | 0.0494974 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0483705 |
| GOLGA4 | golgin A4 | 0.0477838 |
| JMJD1C | jumonji domain containing 1C | 0.0463259 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0460916 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0455383 |
| SIK3 | SIK family kinase 3 | 0.0436619 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0425897 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0418276 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0417336 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.040844 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0406652 |
| HELZ | helicase with zinc finger | 0.0404162 |
| FN1 | fibronectin 1 | 0.0383657 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0379013 |
| COPA | coatomer protein complex, subunit alpha | 0.0376665 |
| TXNIP | thioredoxin interacting protein | 0.0366848 |
| XPO1 | exportin 1 | 0.0363098 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0361258 |
| SUCO | SUN domain containing ossification factor | 0.0355896 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.034424 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0343561 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0340601 |
| RNF145 | ring finger protein 145 | 0.0334502 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0333276 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.033064 |
| RPS2 | ribosomal protein S2 | 0.0327364 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.032462 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0323188 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0321702 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0318202 |
| TFG | TRK-fused gene | 0.0317898 |
| NUP58 | nucleoporin 58 | 0.0316791 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0314436 |
| ANO6 | anoctamin 6 | 0.0308923 |
| USP3 | ubiquitin specific peptidase 3 | 0.0308373 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0308359 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0303718 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.030252 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0301582 |
| BBX | bobby sox homolog (Drosophila) | 0.0299725 |
| DST | dystonin | 0.0297628 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0295705 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0295467 |
| STC1 | stanniocalcin 1 | 0.029093 |
| COG5 | component of oligomeric golgi complex 5 | 0.0290556 |
| PTEN | phosphatase and tensin homolog | 0.0283226 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0281678 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0281516 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.028049 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.027885 |
| ATP13A3 | ATPase type 13A3 | 0.0278775 |
| VEGFA | vascular endothelial growth factor A | 0.0276953 |
| LOX | lysyl oxidase | 0.0275474 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0274625 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0274094 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.027086 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270672 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0270409 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0266581 |
| PHF21A | PHD finger protein 21A | 0.026622 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0265089 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0263468 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0263221 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0262692 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0262373 |
| RIOK3 | RIO kinase 3 | 0.0261495 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.026069 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0260435 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0260134 |
| PLIN2 | perilipin 2 | 0.0257535 |
| MED13L | mediator complex subunit 13-like | 0.0256884 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0255765 |
| HYOU1 | hypoxia up-regulated 1 | 0.0253717 |
| MED13 | mediator complex subunit 13 | 0.0251281 |
| SETD5 | SET domain containing 5 | 0.0250174 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0249974 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0247986 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0246022 |
| OPTN | optineurin | 0.024324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.17578 |
| VIM | vimentin | -0.156822 |
| TMSB10 | thymosin beta 10 | -0.114359 |
| OSMR | oncostatin M receptor | -0.0908342 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0886133 |
| IER3 | immediate early response 3 | -0.0844602 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0747523 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0686382 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0635693 |
| MT2A | metallothionein 2A | -0.0630045 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0607431 |
| FAM20C | family with sequence similarity 20, member C | -0.0569517 |
| CD44 | CD44 molecule (Indian blood group) | -0.0541001 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0492613 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0485935 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0460267 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0457956 |
| RPS19 | ribosomal protein S19 | -0.0445576 |
| NDRG1 | N-myc downstream regulated 1 | -0.0432957 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0428251 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426882 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0410209 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0407482 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0402017 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0401123 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0370853 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0368753 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0354557 |
| ACTN4 | actinin, alpha 4 | -0.0352141 |
| GNAS | GNAS complex locus | -0.0345933 |
| RPS24 | ribosomal protein S24 | -0.0335822 |
| ANXA2 | annexin A2 | -0.0330177 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0325414 |
| RPL36 | ribosomal protein L36 | -0.0321303 |
| RPL35A | ribosomal protein L35a | -0.0313744 |
| H1-0 | H1.0 linker histone | -0.0312107 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0311827 |
| ZNF804A | zinc finger protein 804A | -0.0311005 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0308315 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0307417 |
| RPL23 | ribosomal protein L23 | -0.0305813 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0303197 |
| EGR1 | early growth response 1 | -0.0300679 |
| GLCCI1 | glucocorticoid induced 1 | -0.0300241 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0297259 |
| RPL34 | ribosomal protein L34 | -0.0294642 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0294191 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0292431 |
| RPL37A | ribosomal protein L37a | -0.0289266 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0288517 |
| RPLP2 | ribosomal protein, large, P2 | -0.028814 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0277022 |
| RPS29 | ribosomal protein S29 | -0.0273704 |
| PTMA | prothymosin, alpha | -0.0264445 |
| RPS6 | ribosomal protein S6 | -0.026402 |
| HMGA2 | high mobility group AT-hook 2 | -0.0263256 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0263243 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260625 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0260251 |
| RPS21 | ribosomal protein S21 | -0.0259596 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0256525 |
| RAD51B | RAD51 paralog B | -0.0256024 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0254625 |
| NRP1 | neuropilin 1 | -0.0253751 |
| RPL38 | ribosomal protein L38 | -0.0253153 |
| RPS16 | ribosomal protein S16 | -0.0249642 |
| TXNRD1 | thioredoxin reductase 1 | -0.0248018 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0247404 |
| FRMD4A | FERM domain containing 4A | -0.0246463 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.024431 |
| HLA-B | major histocompatibility complex, class I, B | -0.0243677 |
| RPL32 | ribosomal protein L32 | -0.0241387 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0239674 |
| RPS27A | ribosomal protein S27a | -0.0237606 |
| FTL | ferritin, light polypeptide | -0.0234531 |
| BPTF | bromodomain PHD finger transcription factor | -0.0231856 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0231572 |
| RPL12 | ribosomal protein L12 | -0.0230494 |
| SMAD2 | SMAD family member 2 | -0.0229452 |
| VCL | vinculin | -0.0229227 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0228448 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0228432 |
| RPL31 | ribosomal protein L31 | -0.0226661 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.022524 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0225125 |
| ARF1 | ADP-ribosylation factor 1 | -0.0224335 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0221447 |
| RRBP1 | ribosome binding protein 1 | -0.0221425 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0221309 |
| CCNI | cyclin I | -0.0220538 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0219344 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0216722 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0216114 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0214077 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0213553 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0212325 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0212278 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0211753 |
| GOLGA3 | golgin A3 | -0.0210163 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.020942 |
