| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Silodosin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Silodosin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0932838 |
| PM20D1 | peptidase M20 domain containing 1 | 0.055847 |
| POTEF | POTE ankyrin domain family, member F | 0.0551564 |
| FGB | fibrinogen beta chain | 0.0486835 |
| TPM3 | tropomyosin 3 | 0.0481374 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0438327 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0432198 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0424289 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0384756 |
| VMP1 | vacuole membrane protein 1 | 0.0382079 |
| PCBP2 | poly(rC) binding protein 2 | 0.0380932 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.034435 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0336452 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0320745 |
| UBC | ubiquitin C | 0.0286285 |
| NUP58 | nucleoporin 58 | 0.0253053 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0252283 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0240995 |
| GRAMD1B | GRAM domain containing 1B | 0.0237881 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0231549 |
| HDGF | hepatoma-derived growth factor | 0.0228728 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0223712 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0222846 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0211982 |
| ENO1 | enolase 1, (alpha) | 0.0207141 |
| CCNL1 | cyclin L1 | 0.0204421 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.020436 |
| YTHDC1 | YTH domain containing 1 | 0.0200817 |
| HYOU1 | hypoxia up-regulated 1 | 0.0199901 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0198396 |
| DIAPH1 | diaphanous-related formin 1 | 0.0192437 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0191593 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0179037 |
| PNN | pinin, desmosome associated protein | 0.0176442 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0176263 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0172162 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.017139 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0171205 |
| TCP1 | t-complex 1 | 0.0169881 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0169499 |
| MSN | moesin | 0.0168776 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0166939 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0157771 |
| AXL | AXL receptor tyrosine kinase | 0.0154718 |
| RPL3 | ribosomal protein L3 | 0.015282 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0151368 |
| EXOC5 | exocyst complex component 5 | 0.015108 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0151067 |
| PTEN | phosphatase and tensin homolog | 0.0150679 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0149608 |
| SP3 | Sp3 transcription factor | 0.014663 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0146174 |
| SSRP1 | structure specific recognition protein 1 | 0.0145994 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0145306 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0144528 |
| AATF | apoptosis antagonizing transcription factor | 0.0143552 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.014253 |
| TMF1 | TATA element modulatory factor 1 | 0.0139778 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0139582 |
| GMFB | glia maturation factor, beta | 0.013932 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0137975 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0137049 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0136287 |
| DSE | dermatan sulfate epimerase | 0.0136174 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0135167 |
| TJP1 | tight junction protein 1 | 0.0133803 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0133516 |
| RPS18 | ribosomal protein S18 | 0.0133136 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0132758 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0132429 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0131281 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0131097 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0130462 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0129734 |
| EPN2 | epsin 2 | 0.0128622 |
| RCOR1 | REST corepressor 1 | 0.0127934 |
| RBM25 | RNA binding motif protein 25 | 0.0121301 |
| NAV3 | neuron navigator 3 | 0.0120937 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0120816 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0120617 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0120242 |
| DST | dystonin | 0.0120145 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0120001 |
| CTSL | cathepsin L | 0.0118531 |
| KIF1B | kinesin family member 1B | 0.0118429 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0118071 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0117752 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0117547 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0117408 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.01168 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0116176 |
| ARRDC3 | arrestin domain containing 3 | 0.0115965 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0115421 |
| SET | SET nuclear proto-oncogene | 0.0115284 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0114943 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.011486 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.011458 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0114376 |
| SNX14 | sorting nexin 14 | 0.0114342 |
| YAP1 | Yes-associated protein 1 | 0.0114123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.305558 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.29799 |
| VIM | vimentin | -0.221367 |
| FTL | ferritin, light polypeptide | -0.156632 |
| TMSB10 | thymosin beta 10 | -0.12175 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.093368 |
| IGF2 | insulin-like growth factor 2 | -0.093017 |
| ACTG1 | actin gamma 1 | -0.08699 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0833164 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0829014 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0697517 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0672781 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0672142 |
| IER3 | immediate early response 3 | -0.0637484 |
| RPL23 | ribosomal protein L23 | -0.0617929 |
| CAVIN1 | caveolae associated protein 1 | -0.059243 |
| RPS21 | ribosomal protein S21 | -0.0586863 |
| RBM39 | RNA binding motif protein 39 | -0.0570459 |
| RPL19 | ribosomal protein L19 | -0.0541188 |
| RPLP1 | ribosomal protein, large, P1 | -0.0519837 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0511845 |
| RPL35A | ribosomal protein L35a | -0.0506004 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0504732 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0492993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0452036 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0433152 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0416561 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0399657 |
| RPS19 | ribosomal protein S19 | -0.039259 |
| FUS | FUS RNA binding protein | -0.0386004 |
| PARD3 | par-3 family cell polarity regulator | -0.0373132 |
| SERF2 | small EDRK-rich factor 2 | -0.036988 |
| RPL7 | ribosomal protein L7 | -0.0369312 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0354185 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0348977 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0347636 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0341486 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0340485 |
| PTMA | prothymosin, alpha | -0.0339929 |
| RPL34 | ribosomal protein L34 | -0.0338794 |
| RPS5 | ribosomal protein S5 | -0.0337928 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0334618 |
| RPL8 | ribosomal protein L8 | -0.033086 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0327803 |
| TXNRD1 | thioredoxin reductase 1 | -0.0326879 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0322725 |
| RPL26 | ribosomal protein L26 | -0.0321483 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0320615 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0320057 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0319651 |
| RPS24 | ribosomal protein S24 | -0.0319214 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0314602 |
| PTK2 | protein tyrosine kinase 2 | -0.0310335 |
| RPL36 | ribosomal protein L36 | -0.0299925 |
| GNAS | GNAS complex locus | -0.0293618 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.02924 |
| S100A6 | S100 calcium binding protein A6 | -0.0286221 |
| HDAC9 | histone deacetylase 9 | -0.0285423 |
| RPS8 | ribosomal protein S8 | -0.0282483 |
| ZNF292 | zinc finger protein 292 | -0.0281907 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0281276 |
| RPS23 | ribosomal protein S23 | -0.0277888 |
| RPL38 | ribosomal protein L38 | -0.0276523 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0275968 |
| S100A10 | S100 calcium binding protein A10 | -0.0274573 |
| RPL30 | ribosomal protein L30 | -0.0265412 |
| FBXO11 | F-box protein 11 | -0.0265392 |
| PHF20 | PHD finger protein 20 | -0.026465 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0260586 |
| SRGN | serglycin | -0.0259466 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0259151 |
| OLA1 | Obg-like ATPase 1 | -0.025897 |
| RPL11 | ribosomal protein L11 | -0.0258895 |
| RPLP0 | ribosomal protein, large, P0 | -0.0255297 |
| RPL32 | ribosomal protein L32 | -0.0254909 |
| RPS16 | ribosomal protein S16 | -0.025363 |
| RPS29 | ribosomal protein S29 | -0.0252952 |
| LMNA | lamin A/C | -0.0248879 |
| RPL12 | ribosomal protein L12 | -0.0243385 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0235061 |
| ILF2 | interleukin enhancer binding factor 2 | -0.0234218 |
| CYTH1 | cytohesin 1 | -0.0233432 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0232615 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0228741 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0228511 |
| RPL4 | ribosomal protein L4 | -0.0227864 |
| YBX3 | Y box binding protein 3 | -0.0226356 |
| HLA-B | major histocompatibility complex, class I, B | -0.0226075 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0224578 |
| RPL5 | ribosomal protein L5 | -0.0222858 |
| CFDP1 | craniofacial development protein 1 | -0.0222756 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0221426 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0221255 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0221076 |
| NOP58 | NOP58 ribonucleoprotein | -0.0220236 |
| DENND4A | DENN/MADD domain containing 4A | -0.0216765 |
| OSMR | oncostatin M receptor | -0.0215796 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0215128 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0214907 |
| RPL9 | ribosomal protein L9 | -0.0212482 |
