| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Silodosin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Silodosin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A2 | collagen, type I, alpha 2 | 0.0898127 |
| COL1A1 | collagen, type I, alpha 1 | 0.0693049 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0657323 |
| MT2A | metallothionein 2A | 0.0589521 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0547227 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0406353 |
| FAT1 | FAT atypical cadherin 1 | 0.0382546 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0369718 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.035435 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.035025 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0323773 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0321285 |
| NRG3 | neuregulin 3 | 0.0312886 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0308053 |
| CALD1 | caldesmon 1 | 0.0305048 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0304495 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0296996 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0295994 |
| TPM3 | tropomyosin 3 | 0.0291427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.028947 |
| UBAC2 | UBA domain containing 2 | 0.0286505 |
| MEF2A | myocyte enhancer factor 2A | 0.0284282 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0282851 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0272534 |
| ETV6 | ets variant 6 | 0.0271604 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0265748 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0265541 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0263011 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0262717 |
| KIF1B | kinesin family member 1B | 0.0260299 |
| BICC1 | BicC family RNA binding protein 1 | 0.0259284 |
| MSI2 | musashi RNA-binding protein 2 | 0.0254944 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252823 |
| MX2 | MX dynamin-like GTPase 2 | 0.0252503 |
| SMAD3 | SMAD family member 3 | 0.0247715 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0245262 |
| SETBP1 | SET binding protein 1 | 0.0243184 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0237022 |
| S100A6 | S100 calcium binding protein A6 | 0.0233127 |
| ATP13A3 | ATPase type 13A3 | 0.0232712 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0232266 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0231583 |
| ITGA6 | integrin, alpha 6 | 0.0231072 |
| LDHA | lactate dehydrogenase A | 0.0230243 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0229375 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0227079 |
| TUBB | tubulin, beta class I | 0.0226754 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0225977 |
| ATG10 | autophagy related 10 | 0.0225671 |
| RARB | retinoic acid receptor, beta | 0.0225262 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0225023 |
| CD44 | CD44 molecule (Indian blood group) | 0.0224252 |
| TBK1 | TANK-binding kinase 1 | 0.022351 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0223163 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0222921 |
| PLS3 | plastin 3 | 0.0222091 |
| INHBA | inhibin, beta A | 0.0221411 |
| RBM25 | RNA binding motif protein 25 | 0.022121 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.022108 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0220811 |
| TXNRD1 | thioredoxin reductase 1 | 0.022026 |
| ANKRD13C | ankyrin repeat domain 13C | 0.0219649 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0219547 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0219355 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0219337 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0219021 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0217303 |
| THBS1 | thrombospondin 1 | 0.0216991 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0213271 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0213119 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.021297 |
| VMP1 | vacuole membrane protein 1 | 0.0212917 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0212841 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0212114 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0211021 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0208432 |
| SRPK2 | SRSF protein kinase 2 | 0.0206456 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.020637 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0205421 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 | 0.0204634 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0203901 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0203402 |
| TCF12 | transcription factor 12 | 0.020336 |
| NF1 | neurofibromin 1 | 0.0203156 |
| PLSCR1 | phospholipid scramblase 1 | 0.0202944 |
| SLTM | SAFB-like, transcription modulator | 0.0201233 |
| CCDC14 | coiled-coil domain containing 14 | 0.0200787 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0200529 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0199197 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0198464 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0197961 |
| STK17B | serine/threonine kinase 17b | 0.0197717 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0196003 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0195437 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0195293 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0194943 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0194423 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0194328 |
| SPAG9 | sperm associated antigen 9 | 0.0193728 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0193708 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174982 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143354 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142465 |
| VIM | vimentin | -0.124019 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.122192 |
| COL6A3 | collagen, type VI, alpha 3 | -0.110772 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.10966 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.108249 |
| TMSB10 | thymosin beta 10 | -0.107356 |
| CANX | calnexin | -0.100889 |
| LOX | lysyl oxidase | -0.0893698 |
| HLA-B | major histocompatibility complex, class I, B | -0.0879929 |
| NDRG1 | N-myc downstream regulated 1 | -0.0876901 |
| NRXN3 | neurexin 3 | -0.0870147 |
| CDH13 | cadherin 13 | -0.0832115 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.079653 |
| AHNAK | AHNAK nucleoprotein | -0.0767754 |
| FN1 | fibronectin 1 | -0.0766589 |
| SDC4 | syndecan 4 | -0.062449 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0623245 |
| FAM13A | family with sequence similarity 13, member A | -0.0603846 |
| COL5A1 | collagen, type V, alpha 1 | -0.0563584 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0554845 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0552824 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0548188 |
| STC1 | stanniocalcin 1 | -0.0545283 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0537683 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0528696 |
| CALR | calreticulin | -0.0526528 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.049193 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0488807 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0485887 |
| LOXL2 | lysyl oxidase-like 2 | -0.0483125 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0475851 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0474322 |
| EFNA5 | ephrin-A5 | -0.0469567 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0465504 |
| HM13 | histocompatibility (minor) 13 | -0.0460833 |
| PRELID2 | PRELI domain containing 2 | -0.045135 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.044329 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0442701 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0440254 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0436671 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0430756 |
| COG6 | component of oligomeric golgi complex 6 | -0.0427746 |
| MORF4L2 | mortality factor 4 like 2 | -0.0426096 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0423649 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0420934 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0420836 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0409974 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0397821 |
| GOLGA4 | golgin A4 | -0.0391636 |
| HDLBP | high density lipoprotein binding protein | -0.0386843 |
| HLA-C | major histocompatibility complex, class I, C | -0.0385131 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0384287 |
| HIP1 | huntingtin interacting protein 1 | -0.0375767 |
| PRSS23 | protease, serine, 23 | -0.036936 |
| GOLGB1 | golgin B1 | -0.036667 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0362983 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0351624 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0349671 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0344669 |
| FBXO11 | F-box protein 11 | -0.0343755 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0343152 |
| PTGES2 | prostaglandin E synthase 2 | -0.0343032 |
| CADM1 | cell adhesion molecule 1 | -0.0330659 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0328752 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0327 |
| RUNX1 | runt-related transcription factor 1 | -0.032422 |
| ZNF395 | zinc finger protein 395 | -0.0323924 |
| HMGA2 | high mobility group AT-hook 2 | -0.0321015 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0319532 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0313372 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0309862 |
| CALU | calumenin | -0.0309199 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0308776 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0305401 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0304825 |
| SCFD1 | sec1 family domain containing 1 | -0.0301993 |
| VEGFA | vascular endothelial growth factor A | -0.0301177 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.029884 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0298831 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0297715 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0293879 |
| RPS8 | ribosomal protein S8 | -0.0293258 |
| HLA-A | major histocompatibility complex, class I, A | -0.0292257 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0290631 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0289439 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.028101 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0278549 |
| MCL1 | myeloid cell leukemia 1 | -0.0277337 |
| RPL31 | ribosomal protein L31 | -0.0276644 |
| CLTC | clathrin, heavy chain (Hc) | -0.0267095 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0266521 |
| TBCA | tubulin folding cofactor A | -0.026483 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0264471 |
| INTS6 | integrator complex subunit 6 | -0.0262522 |
| COG5 | component of oligomeric golgi complex 5 | -0.0261502 |
| CDK13 | cyclin-dependent kinase 13 | -0.0261414 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0258802 |
