| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Silodosin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Silodosin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.121039 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.113614 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.10225 |
| AHR | aryl hydrocarbon receptor | 0.0864281 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0670267 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.059334 |
| CENPF | centromere protein F, 350/400kDa | 0.0545971 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0500774 |
| PTK2 | protein tyrosine kinase 2 | 0.0495594 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0468408 |
| CANX | calnexin | 0.0459923 |
| TXNIP | thioredoxin interacting protein | 0.0459889 |
| DST | dystonin | 0.0459113 |
| EREG | epiregulin | 0.0416769 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0402197 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0397662 |
| HMGA2 | high mobility group AT-hook 2 | 0.0391119 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0363751 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0354947 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0353972 |
| ZNF292 | zinc finger protein 292 | 0.0351402 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0328713 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.03276 |
| FAM13A | family with sequence similarity 13, member A | 0.031548 |
| TMEM165 | transmembrane protein 165 | 0.0295318 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.029382 |
| NBAS | neuroblastoma amplified sequence | 0.0288351 |
| RAD51B | RAD51 paralog B | 0.0285306 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0285221 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.028055 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0280339 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0278078 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0270021 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.026883 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0268751 |
| SFXN1 | sideroflexin 1 | 0.0267207 |
| FAT1 | FAT atypical cadherin 1 | 0.0265822 |
| ANXA5 | annexin A5 | 0.0265419 |
| PRELID2 | PRELI domain containing 2 | 0.025838 |
| CAB39 | calcium binding protein 39 | 0.0257907 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0256179 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0255234 |
| ETV6 | ets variant 6 | 0.0254455 |
| FBXO32 | F-box protein 32 | 0.0246795 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0245987 |
| CD109 | CD109 molecule | 0.0241278 |
| WDR26 | WD repeat domain 26 | 0.0240054 |
| TXNRD1 | thioredoxin reductase 1 | 0.0239331 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0236753 |
| TMEM156 | transmembrane protein 156 | 0.0236216 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0235109 |
| RUNX2 | runt-related transcription factor 2 | 0.0234138 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0233318 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0232689 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0226196 |
| SLTM | SAFB-like, transcription modulator | 0.0226045 |
| TFG | TRK-fused gene | 0.0225564 |
| STC2 | stanniocalcin 2 | 0.0223844 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0222305 |
| SP3 | Sp3 transcription factor | 0.0220966 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0219967 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0217067 |
| PTGR1 | prostaglandin reductase 1 | 0.0210489 |
| YME1L1 | YME1-like 1 ATPase | 0.0209811 |
| HDGF | hepatoma-derived growth factor | 0.0206112 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0205338 |
| TPM3 | tropomyosin 3 | 0.0204193 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0203558 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0201951 |
| SMOX | spermine oxidase | 0.0200542 |
| YEATS2 | YEATS domain containing 2 | 0.0196417 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0194715 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.019468 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | 0.0194463 |
| MYOF | myoferlin | 0.0193929 |
| RAB18 | RAB18, member RAS oncogene family | 0.0193606 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0193402 |
| ETNK1 | ethanolamine kinase 1 | 0.0192385 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0192373 |
| STK17B | serine/threonine kinase 17b | 0.0192346 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0192184 |
| PCBP2 | poly(rC) binding protein 2 | 0.0191569 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0191522 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0190684 |
| RO60 | Ro60, Y RNA binding protein | 0.0190556 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0190536 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.019053 |
| ZNF148 | zinc finger protein 148 | 0.0188835 |
| ARF4 | ADP-ribosylation factor 4 | 0.018708 |
| SMAD3 | SMAD family member 3 | 0.0186945 |
| TPX2 | TPX2, microtubule-associated | 0.0186652 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0185543 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0185474 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0184397 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0184152 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0183927 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0182429 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0181465 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0181074 |
| YAP1 | Yes-associated protein 1 | 0.0180659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.435087 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.151697 |
| FN1 | fibronectin 1 | -0.147134 |
| MT2A | metallothionein 2A | -0.134657 |
| FTL | ferritin, light polypeptide | -0.11938 |
| VCL | vinculin | -0.108106 |
| TMSB10 | thymosin beta 10 | -0.0892286 |
| PTMA | prothymosin, alpha | -0.0842781 |
| VIM | vimentin | -0.0841512 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0798859 |
| HLA-B | major histocompatibility complex, class I, B | -0.0776514 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0666823 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0628623 |
| NTN4 | netrin 4 | -0.061299 |
| RPS6 | ribosomal protein S6 | -0.0611052 |
| RPL35A | ribosomal protein L35a | -0.055951 |
| S100A6 | S100 calcium binding protein A6 | -0.0556234 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0553161 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.053527 |
| RPL37A | ribosomal protein L37a | -0.0517431 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0494811 |
| RPS19 | ribosomal protein S19 | -0.0488774 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0457456 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0456636 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0446442 |
| NDRG1 | N-myc downstream regulated 1 | -0.0443799 |
| RPLP1 | ribosomal protein, large, P1 | -0.0435596 |
| PALLD | palladin, cytoskeletal associated protein | -0.0427571 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0414602 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0405182 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0392064 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0391357 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0391268 |
| IER3 | immediate early response 3 | -0.0379485 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0372403 |
| ACTG1 | actin gamma 1 | -0.0368256 |
| GNAS | GNAS complex locus | -0.0367872 |
| S100A10 | S100 calcium binding protein A10 | -0.0350779 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0346467 |
| RPL23 | ribosomal protein L23 | -0.0341708 |
| RPL31 | ribosomal protein L31 | -0.0339499 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0335254 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0323657 |
| RPS27 | ribosomal protein S27 | -0.0317544 |
| RAB10 | RAB10, member RAS oncogene family | -0.0316952 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0307429 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0305666 |
| RPL19 | ribosomal protein L19 | -0.0304369 |
| RPL37 | ribosomal protein L37 | -0.0304107 |
| EGR1 | early growth response 1 | -0.0300546 |
| OSMR | oncostatin M receptor | -0.0297544 |
| RPS12 | ribosomal protein S12 | -0.0296268 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0295117 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0289814 |
| NXN | nucleoredoxin | -0.0286365 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0282185 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0280249 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0278095 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0271625 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0269083 |
| B2M | beta-2-microglobulin | -0.0266733 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0261071 |
| RPLP2 | ribosomal protein, large, P2 | -0.0259729 |
| RPL34 | ribosomal protein L34 | -0.0257661 |
| RPL36 | ribosomal protein L36 | -0.0254698 |
| INTS6 | integrator complex subunit 6 | -0.0254635 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.025439 |
| KSR1 | kinase suppressor of ras 1 | -0.0254234 |
| RPS24 | ribosomal protein S24 | -0.0253433 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0251506 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0248214 |
| RPS29 | ribosomal protein S29 | -0.0246595 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0244056 |
| LMNA | lamin A/C | -0.024362 |
| RPS8 | ribosomal protein S8 | -0.0242514 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0242173 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0240794 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.023923 |
| RPL8 | ribosomal protein L8 | -0.0238647 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0235219 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0233362 |
| RPL11 | ribosomal protein L11 | -0.0233303 |
| FHL2 | four and a half LIM domains 2 | -0.0232977 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0231438 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0226604 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0224203 |
| RPL9 | ribosomal protein L9 | -0.0224186 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0223761 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0222563 |
| YBX3 | Y box binding protein 3 | -0.0222387 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0221416 |
| RPL32 | ribosomal protein L32 | -0.0217865 |
| SYT1 | synaptotagmin I | -0.0216931 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0216136 |
| SDC2 | syndecan 2 | -0.0215575 |
| SETD5 | SET domain containing 5 | -0.0215535 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0215134 |
| ATF6 | activating transcription factor 6 | -0.0212816 |
| TGFB1 | transforming growth factor, beta 1 | -0.0210572 |
| ECE1 | endothelin converting enzyme 1 | -0.0208991 |
