| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Simotinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Simotinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.175191 |
| VCL | vinculin | 0.136407 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.129319 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.10331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.100531 |
| RPLP0 | ribosomal protein, large, P0 | 0.0859106 |
| ZNF292 | zinc finger protein 292 | 0.0797659 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0772871 |
| RPS8 | ribosomal protein S8 | 0.0747639 |
| GOLGA4 | golgin A4 | 0.0727974 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0700555 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0683586 |
| MATR3 | matrin 3 | 0.067316 |
| TXNRD1 | thioredoxin reductase 1 | 0.0658363 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0623264 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0610821 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0601472 |
| EZR | ezrin | 0.0564125 |
| ACTG1 | actin gamma 1 | 0.0562249 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0549534 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0527226 |
| RPL12 | ribosomal protein L12 | 0.052603 |
| LDHA | lactate dehydrogenase A | 0.0508877 |
| JMJD1C | jumonji domain containing 1C | 0.0504659 |
| NBEA | neurobeachin | 0.0496486 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0488256 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0475976 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0474621 |
| DUSP4 | dual specificity phosphatase 4 | 0.0464616 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0464392 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0461147 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0459636 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.045886 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0457583 |
| POTEF | POTE ankyrin domain family, member F | 0.0456088 |
| FLNB | filamin B, beta | 0.0448945 |
| HDAC9 | histone deacetylase 9 | 0.0448106 |
| EXOC6B | exocyst complex component 6B | 0.0440806 |
| NBAS | neuroblastoma amplified sequence | 0.0421247 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0420067 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.0411331 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0403065 |
| PDGFC | platelet derived growth factor C | 0.0399613 |
| ENO1 | enolase 1, (alpha) | 0.0397244 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0394828 |
| TJP1 | tight junction protein 1 | 0.0393236 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0392763 |
| PKM | pyruvate kinase, muscle | 0.0391721 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0386408 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0386312 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0376425 |
| RPL35A | ribosomal protein L35a | 0.0372426 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0370032 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0369578 |
| USP34 | ubiquitin specific peptidase 34 | 0.0366025 |
| GPHN | gephyrin | 0.0363575 |
| RPS24 | ribosomal protein S24 | 0.0362799 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0356793 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0353883 |
| RPL9 | ribosomal protein L9 | 0.0351855 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0351076 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0345267 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0342834 |
| TMSB4X | thymosin beta 4, X-linked | 0.0338905 |
| RPS12 | ribosomal protein S12 | 0.0326522 |
| SESN2 | sestrin 2 | 0.0326 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0324942 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0318002 |
| RPL26 | ribosomal protein L26 | 0.0316488 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.031632 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0315857 |
| RPL11 | ribosomal protein L11 | 0.0315038 |
| PRPF38B | pre-mRNA processing factor 38B | 0.030917 |
| SCFD1 | sec1 family domain containing 1 | 0.0305936 |
| METTL15 | methyltransferase like 15 | 0.0301508 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0301066 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0294614 |
| RPS6 | ribosomal protein S6 | 0.0294368 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0293044 |
| RTN4 | reticulon 4 | 0.0292432 |
| NUP58 | nucleoporin 58 | 0.0291443 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0287729 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0284612 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0283869 |
| OLA1 | Obg-like ATPase 1 | 0.0282975 |
| SQSTM1 | sequestosome 1 | 0.0281237 |
| TPI1 | triosephosphate isomerase 1 | 0.0281048 |
| EHBP1 | EH domain binding protein 1 | 0.0276762 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0271576 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0269123 |
| CDC73 | cell division cycle 73 | 0.0269055 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.026845 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0267444 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.026738 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0267316 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0266601 |
| EVI5 | ecotropic viral integration site 5 | 0.0266097 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0265939 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0265523 |
| NCKAP1 | NCK-associated protein 1 | 0.0264458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.0717371 |
| GLI3 | GLI family zinc finger 3 | -0.068689 |
| MKI67 | marker of proliferation Ki-67 | -0.0497374 |
| FOXP1 | forkhead box P1 | -0.0423056 |
| MT2A | metallothionein 2A | -0.0388062 |
| BMP10 | bone morphogenetic protein 10 | -0.0370372 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0365377 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0346726 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0340903 |
| NAV2 | neuron navigator 2 | -0.0329544 |
| ZNF438 | zinc finger protein 438 | -0.0326809 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.031627 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0315825 |
| ITGA10 | integrin, alpha 10 | -0.0312338 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0296869 |
| RIGI | RNA sensor RIG-I | -0.0294836 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0274653 |
| PDE7B | phosphodiesterase 7B | -0.0274424 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.02728 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0265175 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0264398 |
| B2M | beta-2-microglobulin | -0.0255157 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0245408 |
| SEPTIN9 | septin 9 | -0.024427 |
| RPL19 | ribosomal protein L19 | -0.0242466 |
| CTBP2 | C-terminal binding protein 2 | -0.0230318 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0230022 |
| SP100 | SP100 nuclear antigen | -0.0229365 |
| S100A6 | S100 calcium binding protein A6 | -0.0227541 |
| FTL | ferritin, light polypeptide | -0.0223935 |
| RPS19 | ribosomal protein S19 | -0.0219402 |
| PLSCR1 | phospholipid scramblase 1 | -0.020934 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0206957 |
| PMP22 | peripheral myelin protein 22 | -0.0204618 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.020146 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0200721 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0200335 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0198457 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0198361 |
| RPL38 | ribosomal protein L38 | -0.0198021 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0196925 |
| PTMA | prothymosin, alpha | -0.0195937 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0192523 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0191234 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0189332 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0189188 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0188355 |
| PRR11 | proline rich 11 | -0.018781 |
| PKP4 | plakophilin 4 | -0.0184072 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0183994 |
| PRKCE | protein kinase C, epsilon | -0.0183587 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.018319 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0182854 |
| EFNA5 | ephrin-A5 | -0.018244 |
| ATXN2 | ataxin 2 | -0.017925 |
| RPS29 | ribosomal protein S29 | -0.0177935 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0177029 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0175926 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0175432 |
| RASA3 | RAS p21 protein activator 3 | -0.0172164 |
| MTAP | methylthioadenosine phosphorylase | -0.0171589 |
| AEBP2 | AE binding protein 2 | -0.0171044 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0170883 |
| VRK1 | vaccinia related kinase 1 | -0.0169619 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0169246 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0165325 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.0164814 |
| SRPK2 | SRSF protein kinase 2 | -0.0164545 |
| HLA-B | major histocompatibility complex, class I, B | -0.0164345 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0164261 |
| BMP2K | BMP2 inducible kinase | -0.0163936 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0163918 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0163767 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0161726 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0161631 |
| ANXA1 | annexin A1 | -0.0161442 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0161339 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0160751 |
| PLXNA2 | plexin A2 | -0.0160466 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.015995 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0158642 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0158319 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0157758 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.0157663 |
| HJURP | Holliday junction recognition protein | -0.0157456 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0156672 |
| RRBP1 | ribosome binding protein 1 | -0.0156618 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.0154579 |
| BCOR | BCL6 corepressor | -0.0154002 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0153221 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0152027 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0151786 |
| DENND1A | DENN/MADD domain containing 1A | -0.0151725 |
| MYOF | myoferlin | -0.0150851 |
| APLF | aprataxin and PNKP like factor | -0.0150151 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.0149918 |
| CFDP1 | craniofacial development protein 1 | -0.0148318 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0147904 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0147637 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0147273 |
