| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.185338 |
| AHNAK | AHNAK nucleoprotein | 0.163124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.15492 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.111497 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0880918 |
| COL5A1 | collagen, type V, alpha 1 | 0.0863655 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0820129 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0805855 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0795462 |
| EFNA5 | ephrin-A5 | 0.0768809 |
| EGFR | epidermal growth factor receptor | 0.074929 |
| MAP1B | microtubule-associated protein 1B | 0.0730134 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0708157 |
| ASPH | aspartate beta-hydroxylase | 0.0700145 |
| NAV1 | neuron navigator 1 | 0.0699529 |
| FN1 | fibronectin 1 | 0.069139 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0653802 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0651386 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0639275 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0629573 |
| HDAC9 | histone deacetylase 9 | 0.0629183 |
| S100A10 | S100 calcium binding protein A10 | 0.0545817 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0539982 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.052402 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0508105 |
| SP100 | SP100 nuclear antigen | 0.0503587 |
| FSTL1 | follistatin-like 1 | 0.0502394 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0482341 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0480402 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0476559 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0467823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0460667 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.04604 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0437318 |
| RIGI | RNA sensor RIG-I | 0.0431489 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.042493 |
| PLXNA2 | plexin A2 | 0.0416469 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0414776 |
| CANX | calnexin | 0.0410783 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407531 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0384716 |
| DCLK2 | doublecortin-like kinase 2 | 0.0379677 |
| INTS6 | integrator complex subunit 6 | 0.0378391 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0376285 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.037291 |
| CDK6 | cyclin-dependent kinase 6 | 0.0365682 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0364469 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0357643 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0355414 |
| CALR | calreticulin | 0.035524 |
| ENO1 | enolase 1, (alpha) | 0.0352235 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0350873 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0344357 |
| CYTH3 | cytohesin 3 | 0.0335271 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0334816 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0326546 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0325058 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0322544 |
| DSPP | dentin sialophosphoprotein | 0.0322388 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0315737 |
| PRKCE | protein kinase C, epsilon | 0.0306347 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0302661 |
| VCL | vinculin | 0.0299442 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0298785 |
| KIAA1549L | KIAA1549-like | 0.0298609 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0298193 |
| TPM3 | tropomyosin 3 | 0.0293985 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0293779 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0289552 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0283199 |
| FMN2 | formin 2 | 0.0281915 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0281166 |
| ANXA1 | annexin A1 | 0.0279929 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0277272 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.026476 |
| TLE4 | transducin-like enhancer of split 4 | 0.0262802 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0262634 |
| ANXA2 | annexin A2 | 0.0261411 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0261242 |
| PCDH7 | protocadherin 7 | 0.0258143 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0256335 |
| DIAPH3 | diaphanous-related formin 3 | 0.0255377 |
| SMAD3 | SMAD family member 3 | 0.0254323 |
| CUX1 | cut-like homeobox 1 | 0.025283 |
| LMNA | lamin A/C | 0.0251454 |
| RND3 | Rho family GTPase 3 | 0.0250511 |
| NAV3 | neuron navigator 3 | 0.0249349 |
| PRELID2 | PRELI domain containing 2 | 0.0249031 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249009 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.024796 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0245229 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0244749 |
| RRM2 | ribonucleotide reductase M2 | 0.0244376 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0243142 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0238064 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0236586 |
| SMYD3 | SET and MYND domain containing 3 | 0.0234221 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0232947 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0232473 |
| JMJD1C | jumonji domain containing 1C | 0.0232389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.306507 |
| FBN1 | fibrillin 1 | -0.175906 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.13279 |
| NDRG1 | N-myc downstream regulated 1 | -0.123043 |
| COL1A2 | collagen, type I, alpha 2 | -0.116426 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.10765 |
| LOXL2 | lysyl oxidase-like 2 | -0.0938603 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0863226 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0785417 |
| LOX | lysyl oxidase | -0.0765239 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0731932 |
| STC1 | stanniocalcin 1 | -0.0648846 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0640893 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0628334 |
| MT2A | metallothionein 2A | -0.0626753 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0578203 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0555007 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0543115 |
| PLAT | plasminogen activator, tissue | -0.0527704 |
| MYADM | myeloid-associated differentiation marker | -0.0510248 |
| COL5A2 | collagen, type V, alpha 2 | -0.049717 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0493194 |
| GPC6 | glypican 6 | -0.0481674 |
| B2M | beta-2-microglobulin | -0.0480247 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0474384 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0460069 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0458148 |
| UBC | ubiquitin C | -0.0454768 |
| ATP13A3 | ATPase type 13A3 | -0.0449549 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0430492 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0421912 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0420837 |
| SBF2 | SET binding factor 2 | -0.0403681 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0366848 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0362488 |
| KIFAP3 | kinesin-associated protein 3 | -0.0353229 |
| COL3A1 | collagen, type III, alpha 1 | -0.0351067 |
| THBS2 | thrombospondin 2 | -0.0337377 |
| TMOD1 | tropomodulin 1 | -0.0335111 |
| OPTN | optineurin | -0.0333977 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0323398 |
| FRMD5 | FERM domain containing 5 | -0.0322746 |
| CLU | clusterin | -0.0319196 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0313614 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0304881 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0295897 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0289863 |
| LRRC49 | leucine rich repeat containing 49 | -0.0288746 |
| RBM25 | RNA binding motif protein 25 | -0.0285875 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.0281912 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0280014 |
| MTSS1 | metastasis suppressor 1 | -0.0276575 |
| ARRDC3 | arrestin domain containing 3 | -0.0274429 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0271684 |
| WTAP | Wilms tumor 1 associated protein | -0.0271006 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0269395 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0262163 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0259222 |
| PRKD3 | protein kinase D3 | -0.0250688 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.024966 |
| CD99 | CD99 molecule | -0.0247683 |
| SP3 | Sp3 transcription factor | -0.0245536 |
| NKTR | natural killer cell triggering receptor | -0.0244815 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0238874 |
| FNBP1 | formin binding protein 1 | -0.023675 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0229391 |
| SETD5 | SET domain containing 5 | -0.0228898 |
| SPAG9 | sperm associated antigen 9 | -0.0228143 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0227099 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0223754 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0221883 |
| GOLGA4 | golgin A4 | -0.0221681 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0221424 |
| PTMA | prothymosin, alpha | -0.022051 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0220105 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0220087 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0219262 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.021902 |
| C1D | C1D nuclear receptor corepressor | -0.021798 |
| NGLY1 | N-glycanase 1 | -0.0215975 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0215259 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0214849 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0214181 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0213629 |
| TAPBP | TAP binding protein (tapasin) | -0.0212789 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0210736 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0208146 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0208119 |
| RASA2 | RAS p21 protein activator 2 | -0.020769 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0205742 |
| CTSB | cathepsin B | -0.0205332 |
| ZNF148 | zinc finger protein 148 | -0.0202423 |
| INSIG1 | insulin induced gene 1 | -0.0200445 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0200356 |
| PRRX1 | paired related homeobox 1 | -0.0199548 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0198476 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0197182 |
| VIM | vimentin | -0.0196506 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.019555 |
| OGA | O-GlcNAcase | -0.0195222 |
