| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.18421 |
| TPM3 | tropomyosin 3 | 0.08334 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0796108 |
| MMP12 | matrix metallopeptidase 12 | 0.0770085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0753648 |
| VMP1 | vacuole membrane protein 1 | 0.0739562 |
| RTN4 | reticulon 4 | 0.0696927 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0666073 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0664292 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0623869 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0505213 |
| BRD2 | bromodomain containing 2 | 0.0475278 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0472663 |
| RPL3 | ribosomal protein L3 | 0.0437957 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0436881 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0436489 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0435525 |
| USP34 | ubiquitin specific peptidase 34 | 0.0432616 |
| EZR | ezrin | 0.0430164 |
| ZNF638 | zinc finger protein 638 | 0.0417136 |
| JMJD1C | jumonji domain containing 1C | 0.0415494 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0404445 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0401289 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0389735 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0389571 |
| EXOC6B | exocyst complex component 6B | 0.0385904 |
| CCDC88A | coiled-coil domain containing 88A | 0.0385242 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.037731 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0375721 |
| RRM2 | ribonucleotide reductase M2 | 0.0368026 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0367473 |
| PCM1 | pericentriolar material 1 | 0.0365591 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.03621 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0360471 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0359242 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0359192 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0357989 |
| SON | SON DNA binding protein | 0.0357949 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0355757 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0345121 |
| ZNF148 | zinc finger protein 148 | 0.0343435 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0340068 |
| ZNF292 | zinc finger protein 292 | 0.0337306 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0331806 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0331105 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0324848 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0322702 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0321524 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0320859 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0320258 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0318454 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.031538 |
| ERBIN | erbb2 interacting protein | 0.0311976 |
| NF1 | neurofibromin 1 | 0.0308442 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0307748 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.030547 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0301202 |
| NEBL | nebulette | 0.0300878 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0300659 |
| RSF1 | remodeling and spacing factor 1 | 0.0300268 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0299931 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0299326 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0294898 |
| XPO1 | exportin 1 | 0.0293935 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0285198 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0284262 |
| RUNX1 | runt-related transcription factor 1 | 0.0283274 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0281228 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0278559 |
| OGA | O-GlcNAcase | 0.0278268 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0277891 |
| ATP11A | ATPase, class VI, type 11A | 0.0277643 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0276093 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0274221 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0266276 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0266169 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0265018 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0262684 |
| PHF21A | PHD finger protein 21A | 0.0262633 |
| TXNRD1 | thioredoxin reductase 1 | 0.0261602 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0258753 |
| WWOX | WW domain containing oxidoreductase | 0.0258283 |
| TJP1 | tight junction protein 1 | 0.0256634 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0256338 |
| FNIP1 | folliculin interacting protein 1 | 0.0255265 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0253935 |
| ARFGEF3 | ARFGEF family member 3 | 0.0252335 |
| SERTAD2 | SERTA domain containing 2 | 0.0250904 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0249878 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0249112 |
| ANK2 | ankyrin 2, neuronal | 0.0249032 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0248264 |
| TENM3 | teneurin transmembrane protein 3 | 0.0248014 |
| CCN2 | cellular communication network factor 2 | 0.0247952 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.024722 |
| EFNA5 | ephrin-A5 | 0.0246098 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0245259 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.024522 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0242817 |
| BPTF | bromodomain PHD finger transcription factor | 0.0241276 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.153676 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.150774 |
| NLGN1 | neuroligin 1 | -0.113716 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0789414 |
| RPL35A | ribosomal protein L35a | -0.0728813 |
| NHSL1 | NHS-like 1 | -0.0695642 |
| PTMA | prothymosin, alpha | -0.0692706 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0579886 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0570227 |
| EHBP1 | EH domain binding protein 1 | -0.0559157 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0544237 |
| ACTG1 | actin gamma 1 | -0.0539157 |
| GNAS | GNAS complex locus | -0.0535627 |
| RPS24 | ribosomal protein S24 | -0.0522847 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0506973 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0502899 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0499447 |
| ZNF804A | zinc finger protein 804A | -0.0493085 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0489891 |
| HMGA2 | high mobility group AT-hook 2 | -0.0477537 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0466157 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0453429 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.044812 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0441573 |
| MGAT4C | MGAT4 family, member C | -0.0419475 |
| RASAL2 | RAS protein activator like 2 | -0.0407893 |
| RPL23 | ribosomal protein L23 | -0.0407673 |
| RPL34 | ribosomal protein L34 | -0.0404625 |
| S100A6 | S100 calcium binding protein A6 | -0.0396993 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0395497 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0383345 |
| TUBB | tubulin, beta class I | -0.0378809 |
| RPL26 | ribosomal protein L26 | -0.0372869 |
| CMIP | c-Maf inducing protein | -0.0364514 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0347181 |
| KLF6 | Kruppel-like factor 6 | -0.0346862 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0337876 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0336102 |
| EGR1 | early growth response 1 | -0.0322348 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0320169 |
| LMO7 | LIM domain 7 | -0.0318585 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0317073 |
| RPL31 | ribosomal protein L31 | -0.0314078 |
| RPLP1 | ribosomal protein, large, P1 | -0.0311748 |
| CLDN1 | claudin 1 | -0.029765 |
| PCDH9 | protocadherin 9 | -0.0294576 |
| SYT1 | synaptotagmin I | -0.029449 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0291963 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0283146 |
| S100A10 | S100 calcium binding protein A10 | -0.0280272 |
| EPHA5 | EPH receptor A5 | -0.0279974 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0278696 |
| RPL19 | ribosomal protein L19 | -0.02786 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0278476 |
| BCHE | butyrylcholinesterase | -0.026728 |
| RPL38 | ribosomal protein L38 | -0.0263202 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.026157 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0258019 |
| FAM110C | family with sequence similarity 110, member C | -0.0254942 |
| ANKRD12 | ankyrin repeat domain 12 | -0.025439 |
| RPLP0 | ribosomal protein, large, P0 | -0.0252808 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0247678 |
| ZNF217 | zinc finger protein 217 | -0.0244971 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0244332 |
| RPS20 | ribosomal protein S20 | -0.0243606 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0241849 |
| FTL | ferritin, light polypeptide | -0.0238681 |
| RPL9 | ribosomal protein L9 | -0.02375 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0225823 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0224991 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0223781 |
| FSTL5 | follistatin-like 5 | -0.0222031 |
| GASK1B | golgi associated kinase 1B | -0.0217486 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0215508 |
| CBX3 | chromobox homolog 3 | -0.0213486 |
| MTAP | methylthioadenosine phosphorylase | -0.0210563 |
| AHNAK | AHNAK nucleoprotein | -0.0210236 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0209097 |
| NABP1 | nucleic acid binding protein 1 | -0.0208746 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0206638 |
| RPLP2 | ribosomal protein, large, P2 | -0.0206119 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0204334 |
| TPI1 | triosephosphate isomerase 1 | -0.0203702 |
| RAB10 | RAB10, member RAS oncogene family | -0.0203021 |
| AHR | aryl hydrocarbon receptor | -0.0203001 |
| CANX | calnexin | -0.020208 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.020175 |
| KHSRP | KH-type splicing regulatory protein | -0.0201525 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0200332 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0199958 |
| ARF1 | ADP-ribosylation factor 1 | -0.0199087 |
| MKI67 | marker of proliferation Ki-67 | -0.0197613 |
| PARK7 | parkinson protein 7 | -0.0196675 |
| VCL | vinculin | -0.0194562 |
| RPS21 | ribosomal protein S21 | -0.0192319 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0189636 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0188635 |
| RBM39 | RNA binding motif protein 39 | -0.0187046 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0185504 |
| CUX1 | cut-like homeobox 1 | -0.0184823 |
