| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.195563 |
| INTS6 | integrator complex subunit 6 | 0.126336 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.123453 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.104743 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.099957 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0822649 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0800148 |
| SMAD3 | SMAD family member 3 | 0.0787407 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0778167 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0542785 |
| CANX | calnexin | 0.0533618 |
| GOLGB1 | golgin B1 | 0.0526913 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0494306 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.048754 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0459558 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.042398 |
| COG6 | component of oligomeric golgi complex 6 | 0.0415722 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0410379 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0407965 |
| ANXA2 | annexin A2 | 0.039751 |
| DST | dystonin | 0.0369531 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0364143 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0362288 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0359869 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0343032 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0337361 |
| AHI1 | Abelson helper integration site 1 | 0.0330658 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0329934 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0322697 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0308939 |
| SEC24D | SEC24 family member D | 0.0302139 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0298253 |
| SUCO | SUN domain containing ossification factor | 0.029752 |
| PHF3 | PHD finger protein 3 | 0.0287297 |
| RUNX1 | runt-related transcription factor 1 | 0.0282373 |
| PMM2 | phosphomannomutase 2 | 0.0277665 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0274489 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0269958 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0268479 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0267868 |
| CTBP2 | C-terminal binding protein 2 | 0.0267649 |
| TOX3 | TOX high mobility group box family member 3 | 0.0266082 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0264797 |
| CALU | calumenin | 0.0261622 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0260201 |
| YAP1 | Yes-associated protein 1 | 0.0259857 |
| AHNAK | AHNAK nucleoprotein | 0.0257405 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0256703 |
| COPA | coatomer protein complex, subunit alpha | 0.0256546 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0255521 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0252988 |
| AGR2 | anterior gradient 2 | 0.025215 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0250304 |
| PDZD8 | PDZ domain containing 8 | 0.0242924 |
| SQSTM1 | sequestosome 1 | 0.024282 |
| HM13 | histocompatibility (minor) 13 | 0.0241879 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0241351 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0241251 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0237288 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0236213 |
| HDLBP | high density lipoprotein binding protein | 0.0235451 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0230567 |
| SEC24A | SEC24 family member A | 0.0225431 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0222121 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0221787 |
| DUSP16 | dual specificity phosphatase 16 | 0.0221255 |
| GOLGA3 | golgin A3 | 0.0220996 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0220724 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0219505 |
| ATOSA | atos homolog A | 0.021922 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0217582 |
| UBAP1 | ubiquitin associated protein 1 | 0.0215459 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0214957 |
| LAMB3 | laminin, beta 3 | 0.0212976 |
| HBS1L | HBS1-like translational GTPase | 0.0212196 |
| USP53 | ubiquitin specific peptidase 53 | 0.0210936 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0209929 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0209279 |
| COG3 | component of oligomeric golgi complex 3 | 0.0206413 |
| MAP7 | microtubule-associated protein 7 | 0.0202909 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0200639 |
| SSR1 | signal sequence receptor, alpha | 0.0196164 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0196031 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0195435 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0195025 |
| GALK2 | galactokinase 2 | 0.0195021 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0193749 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0193124 |
| TOP1 | topoisomerase (DNA) I | 0.0192562 |
| PLSCR2 | phospholipid scramblase 2 | 0.0192343 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0192217 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0190898 |
| CALR | calreticulin | 0.0190687 |
| ERLEC1 | endoplasmic reticulum lectin 1 | 0.0190582 |
| KYNU | kynureninase | 0.0189725 |
| UBL3 | ubiquitin-like 3 | 0.0189249 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0187854 |
| CLTC | clathrin, heavy chain (Hc) | 0.0187669 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0186249 |
| ZNF451 | zinc finger protein 451 | 0.0186238 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.20784 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.158393 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.122935 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.111696 |
| LYZ | lysozyme | -0.110772 |
| PTMA | prothymosin, alpha | -0.101154 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0988399 |
| LCN2 | lipocalin 2 | -0.0894117 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0844538 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0820818 |
| HLA-B | major histocompatibility complex, class I, B | -0.081961 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0812397 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0772064 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0706586 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.070319 |
| ERBIN | erbb2 interacting protein | -0.0691097 |
| MX2 | MX dynamin-like GTPase 2 | -0.0676065 |
| EGR1 | early growth response 1 | -0.0661859 |
| TMSB10 | thymosin beta 10 | -0.0637183 |
| NDRG1 | N-myc downstream regulated 1 | -0.061023 |
| MX1 | MX dynamin-like GTPase 1 | -0.0605146 |
| AREG | amphiregulin | -0.0575711 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0563385 |
| KRT19 | keratin 19, type I | -0.0552813 |
| NPSR1 | neuropeptide S receptor 1 | -0.0546182 |
| TXNIP | thioredoxin interacting protein | -0.0530225 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0500061 |
| RPL35A | ribosomal protein L35a | -0.0481394 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.047655 |
| HLA-C | major histocompatibility complex, class I, C | -0.0476193 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0469603 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0453222 |
| PLSCR1 | phospholipid scramblase 1 | -0.0451494 |
| RNF213 | ring finger protein 213 | -0.0436342 |
| ACTG1 | actin gamma 1 | -0.0435938 |
| RPS6 | ribosomal protein S6 | -0.0435391 |
| S100A6 | S100 calcium binding protein A6 | -0.0435158 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0428936 |
| KLF6 | Kruppel-like factor 6 | -0.0427457 |
| HLA-A | major histocompatibility complex, class I, A | -0.0424918 |
| MT2A | metallothionein 2A | -0.0424074 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0421265 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0414128 |
| FTL | ferritin, light polypeptide | -0.0411237 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0410117 |
| CTSD | cathepsin D | -0.0406553 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0403741 |
| SP100 | SP100 nuclear antigen | -0.0400245 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0400126 |
| PMP22 | peripheral myelin protein 22 | -0.0389935 |
| PERP | PERP, TP53 apoptosis effector | -0.0386249 |
| RPL23 | ribosomal protein L23 | -0.0379634 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0379144 |
| RIGI | RNA sensor RIG-I | -0.037145 |
| CLDN4 | claudin 4 | -0.0369204 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0367028 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0366773 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359479 |
| TPI1 | triosephosphate isomerase 1 | -0.0357501 |
| CST3 | cystatin C | -0.0357062 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0348416 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345475 |
| EFHD2 | EF-hand domain family, member D2 | -0.0344668 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0343732 |
| POTEF | POTE ankyrin domain family, member F | -0.0337648 |
| RPS19 | ribosomal protein S19 | -0.0334502 |
| CSTB | cystatin B (stefin B) | -0.0329954 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0328715 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0324654 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0320836 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.031882 |
| S100A11 | S100 calcium binding protein A11 | -0.0318539 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0318056 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0316849 |
| EPCAM | epithelial cell adhesion molecule | -0.0309746 |
| XAF1 | XIAP associated factor 1 | -0.0303828 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0301694 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0301519 |
| LIMA1 | LIM domain and actin binding 1 | -0.0300761 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0299324 |
| ZNF292 | zinc finger protein 292 | -0.0295945 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.029523 |
| NCKAP5 | NCK-associated protein 5 | -0.0293882 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0293706 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0288812 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0284813 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0284368 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0282718 |
| CCNL1 | cyclin L1 | -0.0282661 |
| PKM | pyruvate kinase, muscle | -0.0280408 |
| ENO1 | enolase 1, (alpha) | -0.028036 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0279958 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0272554 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.027195 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0271604 |
| RPL34 | ribosomal protein L34 | -0.0263716 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0263512 |
| LAP3 | leucine aminopeptidase 3 | -0.026348 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0259664 |
| CD2AP | CD2-associated protein | -0.0259146 |
