| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.210849 |
| INTS6 | integrator complex subunit 6 | 0.0956291 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0898515 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0886453 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0846216 |
| ANXA1 | annexin A1 | 0.0834348 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0807155 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0729974 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0671008 |
| MTSS1 | metastasis suppressor 1 | 0.0620539 |
| RAI14 | retinoic acid induced 14 | 0.0604902 |
| JMJD1C | jumonji domain containing 1C | 0.0563861 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.054971 |
| DST | dystonin | 0.0544311 |
| HMGA2 | high mobility group AT-hook 2 | 0.0544184 |
| PTK2 | protein tyrosine kinase 2 | 0.0542537 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0530805 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0526425 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0515124 |
| EFNA5 | ephrin-A5 | 0.050264 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0496995 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0496667 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0478228 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0478116 |
| AHNAK | AHNAK nucleoprotein | 0.047601 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0474604 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0470219 |
| RASAL2 | RAS protein activator like 2 | 0.0457478 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0453892 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0437249 |
| RNF217 | ring finger protein 217 | 0.0430392 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0415896 |
| OXSR1 | oxidative stress responsive 1 | 0.0408443 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0396151 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0394612 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0363887 |
| TSC22D1 | TSC22 domain family, member 1 | 0.036299 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0357202 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.035284 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0351957 |
| PLS3 | plastin 3 | 0.0348065 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0334986 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0334837 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.032842 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0322174 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0320312 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0318607 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0314301 |
| HLA-E | major histocompatibility complex, class I, E | 0.031342 |
| SQLE | squalene epoxidase | 0.0310618 |
| UBC | ubiquitin C | 0.0307566 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0306059 |
| ASPH | aspartate beta-hydroxylase | 0.0301157 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0300732 |
| CTBP2 | C-terminal binding protein 2 | 0.0294526 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0293824 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0291373 |
| TOP1 | topoisomerase (DNA) I | 0.0290732 |
| DIAPH1 | diaphanous-related formin 1 | 0.0289147 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0284268 |
| TXNIP | thioredoxin interacting protein | 0.0281814 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.028131 |
| SIK3 | SIK family kinase 3 | 0.027987 |
| RNF145 | ring finger protein 145 | 0.0277158 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0276865 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0273111 |
| CDK6 | cyclin-dependent kinase 6 | 0.0272068 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0271334 |
| LYST | lysosomal trafficking regulator | 0.0269292 |
| SQSTM1 | sequestosome 1 | 0.0268211 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0263977 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0260515 |
| FMNL2 | formin-like 2 | 0.0259993 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0255201 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.025043 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0246345 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0245966 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0245152 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0244863 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0243496 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0242819 |
| BARX2 | BARX homeobox 2 | 0.0240868 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0239219 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0236507 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0235293 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0235166 |
| MTDH | metadherin | 0.0233818 |
| COPA | coatomer protein complex, subunit alpha | 0.0232943 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0232596 |
| RPL8 | ribosomal protein L8 | 0.0232448 |
| UBAP2 | ubiquitin associated protein 2 | 0.0231773 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0231658 |
| CDK13 | cyclin-dependent kinase 13 | 0.0231635 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0231319 |
| FBXO11 | F-box protein 11 | 0.0230733 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.022983 |
| GOLGB1 | golgin B1 | 0.0229384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0229362 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0229058 |
| YAP1 | Yes-associated protein 1 | 0.0227421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.195674 |
| FLNB | filamin B, beta | -0.175278 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.140173 |
| FOXO1 | forkhead box O1 | -0.0933001 |
| RIN2 | Ras and Rab interactor 2 | -0.0907621 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0842838 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0804289 |
| BCL2L1 | BCL2-like 1 | -0.073934 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0726155 |
| PLAT | plasminogen activator, tissue | -0.0702446 |
| PODXL | podocalyxin-like | -0.0688383 |
| SULF1 | sulfatase 1 | -0.066654 |
| ITGA6 | integrin, alpha 6 | -0.0666523 |
| KIAA1217 | KIAA1217 | -0.0655266 |
| OSMR | oncostatin M receptor | -0.0642832 |
| FOSL1 | FOS-like antigen 1 | -0.0626144 |
| NRG1 | neuregulin 1 | -0.0618537 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0613427 |
| TMSB10 | thymosin beta 10 | -0.0572571 |
| PRELID2 | PRELI domain containing 2 | -0.0546527 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0543548 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0528602 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0523156 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0506733 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0493706 |
| EGR1 | early growth response 1 | -0.0486641 |
| BLCAP | bladder cancer associated protein | -0.0463701 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0460727 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0445083 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0444967 |
| ENO1 | enolase 1, (alpha) | -0.0441758 |
| EPHA2 | EPH receptor A2 | -0.0433059 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0419907 |
| NEK7 | NIMA-related kinase 7 | -0.041405 |
| EMP1 | epithelial membrane protein 1 | -0.0410153 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0409244 |
| CD99 | CD99 molecule | -0.0407442 |
| SYNJ2 | synaptojanin 2 | -0.039175 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0390822 |
| EFHD2 | EF-hand domain family, member D2 | -0.0381833 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0381777 |
| LAMA5 | laminin, alpha 5 | -0.0381154 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0380951 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0377385 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.037508 |
| KIAA0040 | KIAA0040 | -0.0374882 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0368922 |
| LDLR | low density lipoprotein receptor | -0.0364787 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0360756 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0358777 |
| TPM4 | tropomyosin 4 | -0.0357186 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.035035 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0346398 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0345062 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0337098 |
| EHF | ets homologous factor | -0.0336123 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0335905 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0335694 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0334077 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0333873 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0330138 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0328778 |
| CD59 | CD59 molecule, complement regulatory protein | -0.032326 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0322681 |
| TMSB4X | thymosin beta 4, X-linked | -0.0320412 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0319087 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0317585 |
| ANXA11 | annexin A11 | -0.0314897 |
| ACTN4 | actinin, alpha 4 | -0.0314302 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0309363 |
| C4BPB | complement component 4 binding protein, beta | -0.0309278 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0303759 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0301076 |
| CUL4B | cullin 4B | -0.0295016 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0292887 |
| S100A6 | S100 calcium binding protein A6 | -0.029015 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0285514 |
| TNS4 | tensin 4 | -0.028491 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | -0.0283226 |
| CENPF | centromere protein F, 350/400kDa | -0.0282957 |
| RPS21 | ribosomal protein S21 | -0.0281564 |
| LUZP1 | leucine zipper protein 1 | -0.0280786 |
| FLNA | filamin A, alpha | -0.0280185 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0276812 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0273781 |
| LMNA | lamin A/C | -0.0273399 |
| GNAS | GNAS complex locus | -0.0271994 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0267084 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0264538 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.026195 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0260745 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.026021 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0259871 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0259524 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0257395 |
| FOXP1 | forkhead box P1 | -0.0255374 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0252456 |
| PLEC | plectin | -0.0249487 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0248877 |
| CD44 | CD44 molecule (Indian blood group) | -0.0247784 |
