| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sinomenine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.120725 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.120366 |
| TP63 | tumor protein p63 | 0.0870311 |
| CD44 | CD44 molecule (Indian blood group) | 0.0848712 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0790607 |
| DST | dystonin | 0.0748933 |
| VCL | vinculin | 0.0705368 |
| HLA-B | major histocompatibility complex, class I, B | 0.064239 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0641786 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0609093 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.060049 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0577341 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0564497 |
| CAPRIN2 | caprin family member 2 | 0.0527869 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0522689 |
| RUNX1 | runt-related transcription factor 1 | 0.0508623 |
| CADM2 | cell adhesion molecule 2 | 0.0466999 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0454302 |
| EHBP1 | EH domain binding protein 1 | 0.0427215 |
| RIGI | RNA sensor RIG-I | 0.0407127 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0386834 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0385327 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0367228 |
| HDAC9 | histone deacetylase 9 | 0.036423 |
| PRELID2 | PRELI domain containing 2 | 0.0363633 |
| SP100 | SP100 nuclear antigen | 0.0362538 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0356199 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0353028 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0347346 |
| RAD51B | RAD51 paralog B | 0.0324388 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0324321 |
| PLSCR1 | phospholipid scramblase 1 | 0.0322831 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0321634 |
| FMNL2 | formin-like 2 | 0.0321425 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0318723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0314741 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0312237 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0311058 |
| PLK2 | polo-like kinase 2 | 0.0301088 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.028563 |
| B2M | beta-2-microglobulin | 0.0274133 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0270047 |
| TNS3 | tensin 3 | 0.0267885 |
| TXNIP | thioredoxin interacting protein | 0.0258922 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0256288 |
| CFAP299 | cilia and flagella associated protein 299 | 0.025425 |
| RPS12 | ribosomal protein S12 | 0.0253013 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.02523 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0236233 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0232277 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0231117 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0231062 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0230363 |
| LRRC49 | leucine rich repeat containing 49 | 0.0229281 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.022852 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0226741 |
| JMJD1C | jumonji domain containing 1C | 0.0224725 |
| ENO1 | enolase 1, (alpha) | 0.0223145 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0222916 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0222559 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0220707 |
| CUX1 | cut-like homeobox 1 | 0.0219083 |
| RPL37A | ribosomal protein L37a | 0.0217922 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0217645 |
| EXOC4 | exocyst complex component 4 | 0.0212433 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0212375 |
| AEBP2 | AE binding protein 2 | 0.0208173 |
| ZNF644 | zinc finger protein 644 | 0.0208135 |
| FNIP1 | folliculin interacting protein 1 | 0.0207293 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0207287 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.020626 |
| TGM2 | transglutaminase 2 | 0.0204745 |
| PDE10A | phosphodiesterase 10A | 0.020225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0201212 |
| EPHA4 | EPH receptor A4 | 0.0198986 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0197973 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0197514 |
| RSU1 | Ras suppressor protein 1 | 0.0196306 |
| HLA-E | major histocompatibility complex, class I, E | 0.0195077 |
| EFNA5 | ephrin-A5 | 0.0193916 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0192947 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0188103 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0186913 |
| INTS6 | integrator complex subunit 6 | 0.0186653 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0184118 |
| GOLGB1 | golgin B1 | 0.0183081 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0175808 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0175558 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0175542 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0174141 |
| EGFR | epidermal growth factor receptor | 0.0172701 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0170797 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0166614 |
| AGO3 | argonaute RISC catalytic component 3 | 0.01652 |
| ASPH | aspartate beta-hydroxylase | 0.0162362 |
| ETV6 | ets variant 6 | 0.0159701 |
| CMIP | c-Maf inducing protein | 0.0159166 |
| DNER | delta/notch-like EGF repeat containing | 0.0157917 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0157537 |
| TRIM56 | tripartite motif containing 56 | 0.015727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.212837 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174517 |
| VIM | vimentin | -0.127871 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.11106 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.106449 |
| TMSB10 | thymosin beta 10 | -0.106375 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0837881 |
| RPL35A | ribosomal protein L35a | -0.0815084 |
| MT1X | metallothionein 1X | -0.0771072 |
| TXNRD1 | thioredoxin reductase 1 | -0.0707217 |
| PTMA | prothymosin, alpha | -0.0704651 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0672246 |
| FTL | ferritin, light polypeptide | -0.0625621 |
| RAI1 | retinoic acid induced 1 | -0.0507093 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0478669 |
| CENPF | centromere protein F, 350/400kDa | -0.0471984 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0442323 |
| ACTG1 | actin gamma 1 | -0.0440658 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0407739 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.039566 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0395322 |
| KLF6 | Kruppel-like factor 6 | -0.0386009 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0382588 |
| RPS6 | ribosomal protein S6 | -0.0358944 |
| RPL23 | ribosomal protein L23 | -0.035802 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0354869 |
| RPL5 | ribosomal protein L5 | -0.0354508 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.035316 |
| POTEF | POTE ankyrin domain family, member F | -0.0350665 |
| MKI67 | marker of proliferation Ki-67 | -0.0329012 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0328162 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0323736 |
| SPAG9 | sperm associated antigen 9 | -0.031578 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306444 |
| S100A10 | S100 calcium binding protein A10 | -0.0299488 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295657 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0294601 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0292277 |
| TMEM41B | transmembrane protein 41B | -0.0289325 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0289235 |
| SEPTIN7 | septin 7 | -0.0284441 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0284006 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0278946 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0278492 |
| MT1E | metallothionein 1E | -0.0277076 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0275783 |
| EGR1 | early growth response 1 | -0.0269115 |
| EMP1 | epithelial membrane protein 1 | -0.0263181 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0261282 |
| HMGA1 | high mobility group AT-hook 1 | -0.0255518 |
| RBM25 | RNA binding motif protein 25 | -0.0247821 |
| RPL32 | ribosomal protein L32 | -0.0246696 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0245297 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0242241 |
| EZR | ezrin | -0.0241125 |
| RPS23 | ribosomal protein S23 | -0.0239655 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0238608 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0235446 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0232193 |
| FOSL1 | FOS-like antigen 1 | -0.0232024 |
| RPS4X | ribosomal protein S4, X-linked | -0.02302 |
| RPL19 | ribosomal protein L19 | -0.0228169 |
| MTF2 | metal response element binding transcription factor 2 | -0.0226152 |
| TPX2 | TPX2, microtubule-associated | -0.0225816 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0222866 |
| RLF | rearranged L-myc fusion | -0.0222089 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0222069 |
| RPL34 | ribosomal protein L34 | -0.0218163 |
| XPO1 | exportin 1 | -0.0216979 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0216241 |
| NUP58 | nucleoporin 58 | -0.0215859 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0214189 |
| MIS18BP1 | MIS18 binding protein 1 | -0.021379 |
| RPL9 | ribosomal protein L9 | -0.0213285 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0210653 |
| WDR45B | WD repeat domain 45B | -0.0207843 |
| S100A6 | S100 calcium binding protein A6 | -0.0207704 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0207266 |
| BMERB1 | bMERB domain containing 1 | -0.0207059 |
| RPL36 | ribosomal protein L36 | -0.0206503 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0205431 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0203653 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.020194 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0199931 |
| USP34 | ubiquitin specific peptidase 34 | -0.0199111 |
| USP3 | ubiquitin specific peptidase 3 | -0.0194729 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0193825 |
| PRDX1 | peroxiredoxin 1 | -0.0193529 |
| AREG | amphiregulin | -0.0193404 |
| RBM39 | RNA binding motif protein 39 | -0.0192891 |
| SRPK2 | SRSF protein kinase 2 | -0.0191762 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0190907 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0190755 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0189032 |
| CEP170 | centrosomal protein 170kDa | -0.0188932 |
| WDR26 | WD repeat domain 26 | -0.0188452 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0188039 |
| RPLP0 | ribosomal protein, large, P0 | -0.0186499 |
| RPS29 | ribosomal protein S29 | -0.0185468 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0184874 |
