| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.179517 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.11742 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0751075 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0706595 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0623836 |
| SMAD3 | SMAD family member 3 | 0.0622233 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0584668 |
| PRELID2 | PRELI domain containing 2 | 0.0581258 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0559502 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0559435 |
| INTS6 | integrator complex subunit 6 | 0.0558149 |
| HMGA2 | high mobility group AT-hook 2 | 0.0539624 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0531229 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0524948 |
| EFNA5 | ephrin-A5 | 0.0520501 |
| NAV2 | neuron navigator 2 | 0.0503774 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.049605 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0462787 |
| ATXN1 | ataxin 1 | 0.0445098 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0440128 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0434401 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0434202 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0430136 |
| AADAC | arylacetamide deacetylase | 0.0401951 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0382252 |
| RAD51B | RAD51 paralog B | 0.0340175 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0327967 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0323476 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0322627 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0317705 |
| MYO10 | myosin X | 0.0317379 |
| ZNF638 | zinc finger protein 638 | 0.0316337 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0310284 |
| KSR1 | kinase suppressor of ras 1 | 0.0310244 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0301927 |
| RHCG | Rh family, C glycoprotein | 0.0301534 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0297454 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0292726 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0284253 |
| SMYD3 | SET and MYND domain containing 3 | 0.0281374 |
| TOP1 | topoisomerase (DNA) I | 0.0277121 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0272277 |
| MED13 | mediator complex subunit 13 | 0.0272156 |
| IL1R1 | interleukin 1 receptor, type I | 0.027079 |
| FNIP1 | folliculin interacting protein 1 | 0.0270123 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0267386 |
| NABP1 | nucleic acid binding protein 1 | 0.0260898 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.025843 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0257709 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0257676 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0254403 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0252548 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0248295 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0247364 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0246305 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0246023 |
| GPHN | gephyrin | 0.0244947 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0243114 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0242344 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0240768 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0238769 |
| WWOX | WW domain containing oxidoreductase | 0.023758 |
| SIK3 | SIK family kinase 3 | 0.0235281 |
| VMP1 | vacuole membrane protein 1 | 0.0232456 |
| MEIS1 | Meis homeobox 1 | 0.0228434 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0227107 |
| HDAC9 | histone deacetylase 9 | 0.0225616 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0224995 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0224015 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0223187 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0222164 |
| NEBL | nebulette | 0.0220303 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0219555 |
| KLF6 | Kruppel-like factor 6 | 0.02163 |
| USP53 | ubiquitin specific peptidase 53 | 0.0212607 |
| AUTS2 | autism susceptibility candidate 2 | 0.0212583 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0211625 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0211089 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0208386 |
| H1-0 | H1.0 linker histone | 0.0207337 |
| LOXL2 | lysyl oxidase-like 2 | 0.0202784 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0201373 |
| NTN4 | netrin 4 | 0.0201331 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0200249 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0198484 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0197733 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0197516 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0193782 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0193764 |
| DUSP10 | dual specificity phosphatase 10 | 0.0192872 |
| TGM2 | transglutaminase 2 | 0.0191536 |
| VCL | vinculin | 0.0190789 |
| TGFB2 | transforming growth factor, beta 2 | 0.0190657 |
| STK38L | serine/threonine kinase 38 like | 0.0188299 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0187724 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0185905 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0185323 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0185015 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0181448 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0181283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.1829 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.181555 |
| TMSB10 | thymosin beta 10 | -0.16671 |
| FN1 | fibronectin 1 | -0.141777 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.140283 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.116158 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.114058 |
| CDH13 | cadherin 13 | -0.103748 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0956744 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0923796 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0923695 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0890997 |
| MTSS1 | metastasis suppressor 1 | -0.0845953 |
| PCBP2 | poly(rC) binding protein 2 | -0.0820437 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0808503 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0769454 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0753992 |
| MEF2A | myocyte enhancer factor 2A | -0.0748126 |
| PTMA | prothymosin, alpha | -0.0745026 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0730923 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.069568 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0679336 |
| STC1 | stanniocalcin 1 | -0.0677426 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0660304 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0629418 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0608946 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0592916 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0591972 |
| S100A6 | S100 calcium binding protein A6 | -0.0572025 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0571211 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0554794 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0554477 |
| OSMR | oncostatin M receptor | -0.0552049 |
| NRG1 | neuregulin 1 | -0.0551966 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0550096 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.053628 |
| TMEM165 | transmembrane protein 165 | -0.0530527 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0490665 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0458624 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0457685 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0454727 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0446404 |
| USP34 | ubiquitin specific peptidase 34 | -0.0439732 |
| RPL35A | ribosomal protein L35a | -0.0436668 |
| FTL | ferritin, light polypeptide | -0.042824 |
| MECOM | MDS1 and EVI1 complex locus | -0.0421608 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0421299 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0417111 |
| ETV6 | ets variant 6 | -0.0414124 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0413118 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0398869 |
| POTEF | POTE ankyrin domain family, member F | -0.0397099 |
| FNBP1 | formin binding protein 1 | -0.0392714 |
| PRR16 | proline rich 16 | -0.0387589 |
| LOX | lysyl oxidase | -0.0386878 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0384207 |
| TPM4 | tropomyosin 4 | -0.0383358 |
| NAV3 | neuron navigator 3 | -0.038314 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0381613 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0375354 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0374655 |
| CLMP | CXADR-like membrane protein | -0.0373296 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0371809 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0368842 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0366505 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0364714 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.036454 |
| EGR1 | early growth response 1 | -0.0363787 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0356651 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0355122 |
| RPS6 | ribosomal protein S6 | -0.0353946 |
| SNX9 | sorting nexin 9 | -0.0351364 |
| VRK2 | vaccinia related kinase 2 | -0.0350646 |
| B2M | beta-2-microglobulin | -0.0348797 |
| ENO1 | enolase 1, (alpha) | -0.0346775 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343855 |
| IL1B | interleukin 1, beta | -0.034098 |
| VEGFA | vascular endothelial growth factor A | -0.0339949 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0335628 |
| RPS19 | ribosomal protein S19 | -0.0328997 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.032798 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0325874 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0322612 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0320908 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0320574 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0318562 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0316305 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0315054 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0312366 |
| RAI14 | retinoic acid induced 14 | -0.0309784 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0308547 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0308066 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0307927 |
| PRRX1 | paired related homeobox 1 | -0.0307611 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0302637 |
| TMSB4X | thymosin beta 4, X-linked | -0.0301617 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0301453 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0300694 |
| BMERB1 | bMERB domain containing 1 | -0.029893 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.029801 |
