| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.128379 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.10692 |
| LAMA4 | laminin, alpha 4 | 0.083093 |
| PTEN | phosphatase and tensin homolog | 0.0796748 |
| EGFR | epidermal growth factor receptor | 0.0784824 |
| SMAD3 | SMAD family member 3 | 0.0782139 |
| RASAL2 | RAS protein activator like 2 | 0.0711071 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0677149 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.066535 |
| ABLIM1 | actin binding LIM protein 1 | 0.066099 |
| SSH2 | slingshot protein phosphatase 2 | 0.0654087 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0639134 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0604272 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0574066 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0572157 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0571709 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0562851 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0548355 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0543433 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0543383 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0537992 |
| DUSP5 | dual specificity phosphatase 5 | 0.0537261 |
| MYOF | myoferlin | 0.0534239 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.053098 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0527631 |
| FLNB | filamin B, beta | 0.0524424 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.052354 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0521853 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0521575 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0479449 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.047351 |
| RCOR1 | REST corepressor 1 | 0.0471515 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.046953 |
| LYST | lysosomal trafficking regulator | 0.0458787 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.045862 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0457273 |
| PCM1 | pericentriolar material 1 | 0.0455202 |
| ATF6 | activating transcription factor 6 | 0.0452486 |
| DTNA | dystrobrevin, alpha | 0.044592 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0444971 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0437665 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0434389 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0431673 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0423522 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0419707 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0419378 |
| PHF21A | PHD finger protein 21A | 0.0418777 |
| ITSN2 | intersectin 2 | 0.0418462 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0417359 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0414091 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0410868 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0407488 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0407249 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0406954 |
| PCBP2 | poly(rC) binding protein 2 | 0.0404846 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.04034 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0398692 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0397881 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0397055 |
| SLK | STE20-like kinase | 0.0395175 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0391109 |
| GDNF | glial cell derived neurotrophic factor | 0.0388823 |
| FOXJ3 | forkhead box J3 | 0.0387983 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.038719 |
| SRPK2 | SRSF protein kinase 2 | 0.0384234 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0383121 |
| TPD52 | tumor protein D52 | 0.0379921 |
| TOP1 | topoisomerase (DNA) I | 0.0379573 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0375572 |
| RIN2 | Ras and Rab interactor 2 | 0.0371368 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0370455 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0368519 |
| CDK14 | cyclin-dependent kinase 14 | 0.0367391 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0366465 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0365286 |
| FAM13A | family with sequence similarity 13, member A | 0.0364274 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0362865 |
| SBF2 | SET binding factor 2 | 0.036242 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0359408 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0358592 |
| SQSTM1 | sequestosome 1 | 0.0357981 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0354673 |
| ANO6 | anoctamin 6 | 0.0353475 |
| FMNL2 | formin-like 2 | 0.0352687 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0351781 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0351385 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0349973 |
| SIK3 | SIK family kinase 3 | 0.0348344 |
| SETD5 | SET domain containing 5 | 0.0346456 |
| RPS12 | ribosomal protein S12 | 0.0346281 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0344384 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0340902 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0340894 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0340025 |
| FRMD5 | FERM domain containing 5 | 0.0337706 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0337552 |
| GLCCI1 | glucocorticoid induced 1 | 0.0336382 |
| ITGA6 | integrin, alpha 6 | 0.0335576 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0334915 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0333716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156921 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.123781 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.115679 |
| TMSB10 | thymosin beta 10 | -0.0968137 |
| MYO1E | myosin IE | -0.0959622 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0943558 |
| VIM | vimentin | -0.0899886 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0894352 |
| POTEF | POTE ankyrin domain family, member F | -0.082322 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0804682 |
| SMYD3 | SET and MYND domain containing 3 | -0.0792657 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0773078 |
| LMO7 | LIM domain 7 | -0.0769515 |
| ATOSA | atos homolog A | -0.0768289 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0746322 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0722072 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.071954 |
| S100A9 | S100 calcium binding protein A9 | -0.0707105 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0704226 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0700298 |
| ZNF217 | zinc finger protein 217 | -0.068481 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0680287 |
| INHBA | inhibin, beta A | -0.0672625 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0669529 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0664033 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0652088 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0643675 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0632972 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0628505 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0621915 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0618952 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0617904 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0617348 |
| S100A10 | S100 calcium binding protein A10 | -0.0608138 |
| VCAN | versican | -0.0598641 |
| RAD51B | RAD51 paralog B | -0.0590831 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0589265 |
| STC1 | stanniocalcin 1 | -0.0565265 |
| RNF213 | ring finger protein 213 | -0.056494 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0563902 |
| ANXA2 | annexin A2 | -0.0563894 |
| GRAMD2B | GRAM domain containing 2B | -0.0556576 |
| HLA-A | major histocompatibility complex, class I, A | -0.0542205 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0540423 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0539091 |
| FN1 | fibronectin 1 | -0.0538258 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0534824 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0533898 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0533162 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0525226 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.05229 |
| RPL34 | ribosomal protein L34 | -0.0521848 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0515917 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0513762 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0512912 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0509058 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.050314 |
| GRAMD1B | GRAM domain containing 1B | -0.0502993 |
| TXNIP | thioredoxin interacting protein | -0.0502765 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0499328 |
| HLA-B | major histocompatibility complex, class I, B | -0.048775 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0481674 |
| GLIS3 | GLIS family zinc finger 3 | -0.0477555 |
| MYO5C | myosin VC | -0.0474686 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0470003 |
| PTMA | prothymosin, alpha | -0.0468059 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0465058 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0463214 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0461707 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0461527 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0458244 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0455242 |
| B2M | beta-2-microglobulin | -0.0453356 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0452082 |
| DSG2 | desmoglein 2 | -0.0445072 |
| OSMR | oncostatin M receptor | -0.0433808 |
| CD44 | CD44 molecule (Indian blood group) | -0.0432684 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.043162 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0429595 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0429124 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0427036 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0420219 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.041219 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0411463 |
| RPL35A | ribosomal protein L35a | -0.0410841 |
| BPTF | bromodomain PHD finger transcription factor | -0.040878 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0404226 |
| RRBP1 | ribosome binding protein 1 | -0.0401655 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0401366 |
| POU2F1 | POU class 2 homeobox 1 | -0.0392498 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0390926 |
| CDK13 | cyclin-dependent kinase 13 | -0.0390487 |
| RBM47 | RNA binding motif protein 47 | -0.0388614 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0387986 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0386306 |
| TLK1 | tousled-like kinase 1 | -0.0386183 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0385765 |
| PKM | pyruvate kinase, muscle | -0.038508 |
| RPLP1 | ribosomal protein, large, P1 | -0.0383959 |
| CDCP1 | CUB domain containing protein 1 | -0.0383598 |
