| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0959848 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0727536 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602877 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0595075 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0582989 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0492177 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0481284 |
| TJP1 | tight junction protein 1 | 0.0465016 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0451004 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0434964 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0433114 |
| DSPP | dentin sialophosphoprotein | 0.0423542 |
| ANXA1 | annexin A1 | 0.0410459 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0392131 |
| USP53 | ubiquitin specific peptidase 53 | 0.03852 |
| RBM25 | RNA binding motif protein 25 | 0.0370992 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0368456 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0365491 |
| GOLGB1 | golgin B1 | 0.035231 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0346092 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0333889 |
| TPM3 | tropomyosin 3 | 0.0333196 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0332944 |
| SIK3 | SIK family kinase 3 | 0.0320524 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0311221 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0311133 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0306105 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.029123 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0286281 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0282596 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0280417 |
| SEPTIN11 | septin 11 | 0.0273808 |
| DST | dystonin | 0.0271351 |
| PGBD5 | piggyBac transposable element derived 5 | 0.026514 |
| HMGB2 | high mobility group box 2 | 0.0264921 |
| INTS6 | integrator complex subunit 6 | 0.0263073 |
| HDAC9 | histone deacetylase 9 | 0.0262457 |
| CENPF | centromere protein F, 350/400kDa | 0.0259544 |
| ERBIN | erbb2 interacting protein | 0.025782 |
| VCL | vinculin | 0.0254955 |
| CUL3 | cullin 3 | 0.0252763 |
| CALU | calumenin | 0.0250764 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0248949 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0246923 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0246625 |
| MCU | mitochondrial calcium uniporter | 0.0245072 |
| TBC1D15 | TBC1 domain family, member 15 | 0.024045 |
| BRD2 | bromodomain containing 2 | 0.0240086 |
| FNIP1 | folliculin interacting protein 1 | 0.0239662 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0235532 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0233962 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0231636 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0227439 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0226675 |
| TMF1 | TATA element modulatory factor 1 | 0.0223988 |
| TUFT1 | tuftelin 1 | 0.0222916 |
| DSG2 | desmoglein 2 | 0.022249 |
| VGLL3 | vestigial-like family member 3 | 0.022001 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0217929 |
| NUP98 | nucleoporin 98kDa | 0.0209666 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0207992 |
| FBXO11 | F-box protein 11 | 0.0207113 |
| MED13 | mediator complex subunit 13 | 0.0206808 |
| IFRD1 | interferon-related developmental regulator 1 | 0.020485 |
| SERINC5 | serine incorporator 5 | 0.0203555 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0203342 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0202971 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0202503 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0201965 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0200812 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0200631 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0200034 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0199781 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0199051 |
| RIGI | RNA sensor RIG-I | 0.0198904 |
| ETV6 | ets variant 6 | 0.0198522 |
| MSN | moesin | 0.0196695 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0194824 |
| MCL1 | myeloid cell leukemia 1 | 0.0194175 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0193989 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0193235 |
| MYO1D | myosin ID | 0.0192213 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0191663 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0190288 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0189983 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0189257 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.018872 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0188391 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0187449 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0187053 |
| SON | SON DNA binding protein | 0.018687 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0186571 |
| PSEN1 | presenilin 1 | 0.0186349 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0186288 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0185764 |
| MAP1B | microtubule-associated protein 1B | 0.0183436 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0182648 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.018192 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0181205 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0180743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.272515 |
| NDRG1 | N-myc downstream regulated 1 | -0.248561 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21549 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.140254 |
| POTEF | POTE ankyrin domain family, member F | -0.121906 |
| ACTG1 | actin gamma 1 | -0.105252 |
| S100A6 | S100 calcium binding protein A6 | -0.101641 |
| TMSB10 | thymosin beta 10 | -0.0976928 |
| RPL35A | ribosomal protein L35a | -0.0914127 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0894431 |
| ASPH | aspartate beta-hydroxylase | -0.0881017 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.087215 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0867959 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0843039 |
| FTL | ferritin, light polypeptide | -0.0831757 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0788566 |
| HMGA1 | high mobility group AT-hook 1 | -0.0766207 |
| TOP1 | topoisomerase (DNA) I | -0.0737943 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.071616 |
| PTMA | prothymosin, alpha | -0.069905 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0692866 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0689407 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0655118 |
| LMO7 | LIM domain 7 | -0.0652718 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0639532 |
| PGK1 | phosphoglycerate kinase 1 | -0.0619703 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0612234 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0584241 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0569821 |
| RPL34 | ribosomal protein L34 | -0.0561152 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0558257 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0546043 |
| RPL8 | ribosomal protein L8 | -0.0530959 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0528264 |
| CCND1 | cyclin D1 | -0.0500874 |
| S100A10 | S100 calcium binding protein A10 | -0.0500464 |
| RPL23 | ribosomal protein L23 | -0.0498719 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0497208 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0496818 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0493026 |
| GNAS | GNAS complex locus | -0.0478668 |
| KRT7 | keratin 7, type II | -0.0478132 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0476944 |
| EFNA5 | ephrin-A5 | -0.0470065 |
| ANXA2 | annexin A2 | -0.0457317 |
| TMSB4X | thymosin beta 4, X-linked | -0.0456259 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455323 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.04535 |
| RPS23 | ribosomal protein S23 | -0.0443584 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0440724 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0432624 |
| KLF6 | Kruppel-like factor 6 | -0.0432343 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0429849 |
| RPL32 | ribosomal protein L32 | -0.0428833 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0423625 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0418941 |
| RPS19 | ribosomal protein S19 | -0.0416561 |
| CTSB | cathepsin B | -0.040308 |
| FAM3C | family with sequence similarity 3, member C | -0.039764 |
| TMEM123 | transmembrane protein 123 | -0.0394236 |
| FAM162A | family with sequence similarity 162, member A | -0.0393179 |
| PKM | pyruvate kinase, muscle | -0.0390814 |
| CDCP1 | CUB domain containing protein 1 | -0.0388888 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0385784 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0375202 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0370085 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.036806 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0362769 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0361969 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0360397 |
| CD2AP | CD2-associated protein | -0.0359302 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.035877 |
| RPL11 | ribosomal protein L11 | -0.0357695 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0357038 |
| RPS24 | ribosomal protein S24 | -0.0356562 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0355937 |
| RPS6 | ribosomal protein S6 | -0.0355263 |
| TKT | transketolase | -0.0354835 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0349419 |
| TMEM165 | transmembrane protein 165 | -0.0343932 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0342757 |
| CD47 | CD47 molecule | -0.0342073 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0340855 |
| RPS21 | ribosomal protein S21 | -0.0329522 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0325386 |
| RPL19 | ribosomal protein L19 | -0.0322498 |
| ARRDC3 | arrestin domain containing 3 | -0.0320495 |
| TXNRD1 | thioredoxin reductase 1 | -0.0319881 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0313102 |
| RACK1 | receptor for activated C kinase 1 | -0.0312912 |
| MXD1 | MAX dimerization protein 1 | -0.0311837 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0311643 |
| AHNAK | AHNAK nucleoprotein | -0.0311256 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0310943 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0309869 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0309653 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0309562 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | -0.0303393 |
| HDLBP | high density lipoprotein binding protein | -0.0303016 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0302546 |
