| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.135433 |
| DST | dystonin | 0.12687 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.115513 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.112689 |
| KYNU | kynureninase | 0.0973925 |
| EFNA5 | ephrin-A5 | 0.0927091 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.069572 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0627853 |
| INTS6 | integrator complex subunit 6 | 0.061237 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.060106 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0578173 |
| DNER | delta/notch-like EGF repeat containing | 0.0571979 |
| SMAD2 | SMAD family member 2 | 0.0567673 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0551651 |
| PCBP3 | poly(rC) binding protein 3 | 0.05478 |
| RAD51B | RAD51 paralog B | 0.0534678 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0529725 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0502515 |
| PDE10A | phosphodiesterase 10A | 0.0495516 |
| FMNL2 | formin-like 2 | 0.0431185 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0413838 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0383404 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0376657 |
| PTEN | phosphatase and tensin homolog | 0.0367083 |
| EXOC4 | exocyst complex component 4 | 0.0362423 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0362396 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0361974 |
| HDAC4 | histone deacetylase 4 | 0.0361587 |
| FNIP1 | folliculin interacting protein 1 | 0.0352267 |
| AUTS2 | autism susceptibility candidate 2 | 0.0342696 |
| VCL | vinculin | 0.03418 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0338224 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0335149 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0322815 |
| MCL1 | myeloid cell leukemia 1 | 0.0322313 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0318759 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0314312 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0311821 |
| CUX1 | cut-like homeobox 1 | 0.0300036 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0294947 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279762 |
| PRKCA | protein kinase C, alpha | 0.0267742 |
| TOP1 | topoisomerase (DNA) I | 0.0264373 |
| PDE7B | phosphodiesterase 7B | 0.0254532 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.025143 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0237455 |
| ATM | ATM serine/threonine kinase | 0.0236416 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0229271 |
| GPC6 | glypican 6 | 0.0228021 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.022446 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0223901 |
| MYPN | myopalladin | 0.0222997 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.022197 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0220693 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.022027 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.021978 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.021859 |
| ZNF638 | zinc finger protein 638 | 0.0218223 |
| CTBP2 | C-terminal binding protein 2 | 0.0217588 |
| COPA | coatomer protein complex, subunit alpha | 0.0215176 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0212571 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0212076 |
| MT2A | metallothionein 2A | 0.0211749 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0211572 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0211393 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0210803 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0209898 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0204252 |
| ATXN1 | ataxin 1 | 0.0204136 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0204015 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0203698 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0202031 |
| GDA | guanine deaminase | 0.0198412 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0197514 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.019477 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0194689 |
| AEBP2 | AE binding protein 2 | 0.0191462 |
| SSH2 | slingshot protein phosphatase 2 | 0.0190737 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0189471 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0189145 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0187309 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0186229 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0184453 |
| NRDC | nardilysin convertase | 0.0183656 |
| GRAMD1B | GRAM domain containing 1B | 0.0182685 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0182043 |
| CDK13 | cyclin-dependent kinase 13 | 0.0178936 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0178345 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0177597 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0177018 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0175321 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0172897 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0169954 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0169439 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0168487 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0164181 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0163814 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0163255 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0162795 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0162785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.23095 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.139452 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.114283 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.102706 |
| PTMA | prothymosin, alpha | -0.0913543 |
| MYOF | myoferlin | -0.0853423 |
| CDH13 | cadherin 13 | -0.0820636 |
| TXNRD1 | thioredoxin reductase 1 | -0.0774148 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0759956 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0758511 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0720706 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0706731 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.069736 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0684133 |
| CD109 | CD109 molecule | -0.0630449 |
| NRCAM | neuronal cell adhesion molecule | -0.0575963 |
| NEK7 | NIMA-related kinase 7 | -0.0567675 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0542528 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0529542 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0528212 |
| TMSB10 | thymosin beta 10 | -0.052627 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0526148 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0519943 |
| RPLP1 | ribosomal protein, large, P1 | -0.0517286 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0507666 |
| RPL35A | ribosomal protein L35a | -0.0502615 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0487762 |
| VIM | vimentin | -0.0487274 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0483704 |
| LSAMP | limbic system-associated membrane protein | -0.0474641 |
| RPS24 | ribosomal protein S24 | -0.047178 |
| SPAG9 | sperm associated antigen 9 | -0.0469218 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0454034 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0448385 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0443189 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0436964 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0428959 |
| RPS6 | ribosomal protein S6 | -0.0421946 |
| RTN4 | reticulon 4 | -0.0418949 |
| EZR | ezrin | -0.0418262 |
| RPL26 | ribosomal protein L26 | -0.0415187 |
| COL5A2 | collagen, type V, alpha 2 | -0.0414738 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0402868 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0402372 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0399855 |
| RPL38 | ribosomal protein L38 | -0.0382691 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0380129 |
| RGS2 | regulator of G-protein signaling 2 | -0.0370406 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0368277 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0356624 |
| PRSS23 | protease, serine, 23 | -0.035261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0343625 |
| TNPO1 | transportin 1 | -0.0342466 |
| RPL12 | ribosomal protein L12 | -0.034154 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0337235 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0332956 |
| FTL | ferritin, light polypeptide | -0.0331697 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0331378 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0323353 |
| ASPH | aspartate beta-hydroxylase | -0.0321681 |
| INHBA | inhibin, beta A | -0.0319719 |
| ANXA5 | annexin A5 | -0.0319572 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0318602 |
| RPL31 | ribosomal protein L31 | -0.0317731 |
| CCDC68 | coiled-coil domain containing 68 | -0.0317426 |
| ANXA2 | annexin A2 | -0.0315263 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0313614 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0313364 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0311645 |
| TBXT | T-box transcription factor T | -0.0301159 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.029618 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0295538 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0292024 |
| TPM4 | tropomyosin 4 | -0.0291232 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0290152 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0288294 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0288093 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0287379 |
| RBM39 | RNA binding motif protein 39 | -0.0287278 |
| NDRG1 | N-myc downstream regulated 1 | -0.0286385 |
| RPS2 | ribosomal protein S2 | -0.0285359 |
| RPL37A | ribosomal protein L37a | -0.0285118 |
| MATR3 | matrin 3 | -0.0281528 |
| RPS19 | ribosomal protein S19 | -0.02812 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0279915 |
| IER3 | immediate early response 3 | -0.0275975 |
| OSMR | oncostatin M receptor | -0.0275155 |
| RPL36A | ribosomal protein L36a | -0.0273334 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0273289 |
| PRKD3 | protein kinase D3 | -0.0270485 |
| RPL34 | ribosomal protein L34 | -0.0269761 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0269558 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0267919 |
| ALPK2 | alpha-kinase 2 | -0.0264865 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0262996 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0260548 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0258574 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0257605 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0254148 |
| B2M | beta-2-microglobulin | -0.0253629 |
