| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.152214 |
| FTL | ferritin, light polypeptide | 0.144443 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.141441 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.131834 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.128647 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.122174 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.114258 |
| GLG1 | golgi glycoprotein 1 | 0.111095 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.108336 |
| EFNA5 | ephrin-A5 | 0.107036 |
| DENND1A | DENN/MADD domain containing 1A | 0.0995484 |
| MED13L | mediator complex subunit 13-like | 0.0971092 |
| RPS12 | ribosomal protein S12 | 0.0947711 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0944707 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0942776 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0902252 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0901044 |
| FAT1 | FAT atypical cadherin 1 | 0.0883097 |
| RPS3 | ribosomal protein S3 | 0.0872044 |
| TPM4 | tropomyosin 4 | 0.0871804 |
| HLA-B | major histocompatibility complex, class I, B | 0.0865694 |
| IGF2 | insulin-like growth factor 2 | 0.0862807 |
| MT2A | metallothionein 2A | 0.0852833 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0812275 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0803013 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0802012 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.073561 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0699544 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0689115 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0684889 |
| OGA | O-GlcNAcase | 0.0675186 |
| LMO7 | LIM domain 7 | 0.0657384 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.065372 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0650884 |
| DIAPH1 | diaphanous-related formin 1 | 0.0639497 |
| GOLGA4 | golgin A4 | 0.0596216 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0580321 |
| RPL37A | ribosomal protein L37a | 0.057488 |
| ZNF292 | zinc finger protein 292 | 0.0570942 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0569214 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0553376 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.054218 |
| DST | dystonin | 0.0541957 |
| SFTPA2 | surfactant protein A2 | 0.0540476 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0494465 |
| RPL26 | ribosomal protein L26 | 0.0487477 |
| USP34 | ubiquitin specific peptidase 34 | 0.0470649 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0456013 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0447481 |
| SMAD3 | SMAD family member 3 | 0.0442979 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0422678 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0414502 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0411893 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.040907 |
| OSMR | oncostatin M receptor | 0.0406627 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0405579 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0399699 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0395033 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0387417 |
| PGK1 | phosphoglycerate kinase 1 | 0.0379428 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0362961 |
| SPAG9 | sperm associated antigen 9 | 0.0344847 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0334385 |
| RPL37 | ribosomal protein L37 | 0.0332808 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0327046 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0321372 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0318255 |
| RPS6 | ribosomal protein S6 | 0.0305289 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0284711 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0282564 |
| TMEM165 | transmembrane protein 165 | 0.0279222 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0264061 |
| EZR | ezrin | 0.0263063 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0261795 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0249429 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0242921 |
| STK24 | serine/threonine kinase 24 | 0.0240811 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0223269 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0223226 |
| SBF2 | SET binding factor 2 | 0.0222372 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0214621 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0211881 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.021079 |
| MYO6 | myosin VI | 0.0210242 |
| AHNAK | AHNAK nucleoprotein | 0.0205169 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.019927 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0196036 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0194721 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0193292 |
| FLNB | filamin B, beta | 0.0189288 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0179584 |
| RPL23 | ribosomal protein L23 | 0.0176889 |
| RPS8 | ribosomal protein S8 | 0.0171681 |
| ASPH | aspartate beta-hydroxylase | 0.0164937 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0164105 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0154294 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.015129 |
| TMSB10 | thymosin beta 10 | 0.0146838 |
| ENO1 | enolase 1, (alpha) | 0.0144837 |
| TOP1 | topoisomerase (DNA) I | 0.0131561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.315273 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.125426 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.119378 |
| MMP1 | matrix metallopeptidase 1 | -0.114664 |
| JMJD1C | jumonji domain containing 1C | -0.102432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.102384 |
| CLTC | clathrin, heavy chain (Hc) | -0.101545 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0983421 |
| NF1 | neurofibromin 1 | -0.0960898 |
| INHBA | inhibin, beta A | -0.0881909 |
| GPHN | gephyrin | -0.0792727 |
| MYO10 | myosin X | -0.078213 |
| PTMA | prothymosin, alpha | -0.0771478 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.076927 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.075093 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0747426 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0737715 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.072919 |
| BPTF | bromodomain PHD finger transcription factor | -0.0722794 |
| LAMB3 | laminin, beta 3 | -0.0721472 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0690255 |
| HMGA2 | high mobility group AT-hook 2 | -0.0680619 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0673721 |
| SLTM | SAFB-like, transcription modulator | -0.0662337 |
| NDRG1 | N-myc downstream regulated 1 | -0.0660278 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0626808 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0624828 |
| MYO1E | myosin IE | -0.0613127 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0595386 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0594133 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0587544 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0578407 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0543763 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0541538 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0536881 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0527867 |
| ATXN1 | ataxin 1 | -0.0526953 |
| PDE10A | phosphodiesterase 10A | -0.0526674 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523919 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0523729 |
| PRELID2 | PRELI domain containing 2 | -0.0497436 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.049707 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0494569 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0479441 |
| RPL19 | ribosomal protein L19 | -0.0475643 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0465153 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0462809 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0451573 |
| EGFR | epidermal growth factor receptor | -0.0450179 |
| HELZ | helicase with zinc finger | -0.0449202 |
| FN1 | fibronectin 1 | -0.0443259 |
| PTK2 | protein tyrosine kinase 2 | -0.0433433 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0432088 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0430745 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0425836 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0419134 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0412514 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0390835 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0390168 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0380266 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0375169 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0371873 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0359592 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0353585 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0344845 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0312102 |
| FAM13A | family with sequence similarity 13, member A | -0.0298 |
| GPC6 | glypican 6 | -0.0293655 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0287686 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.028696 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0285491 |
| RNF213 | ring finger protein 213 | -0.0284218 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0239484 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0235724 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0223502 |
| CUX1 | cut-like homeobox 1 | -0.0206719 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0205517 |
| RPLP1 | ribosomal protein, large, P1 | -0.0193564 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0193117 |
| LDHA | lactate dehydrogenase A | -0.019057 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0190034 |
| CDH13 | cadherin 13 | -0.0188936 |
| LAMA4 | laminin, alpha 4 | -0.018256 |
| CD44 | CD44 molecule (Indian blood group) | -0.0177235 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.015379 |
| FNIP1 | folliculin interacting protein 1 | -0.0153155 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0148001 |
| CAVIN1 | caveolae associated protein 1 | -0.014778 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0146595 |
| NRXN3 | neurexin 3 | -0.0142174 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.014157 |
| GOLGB1 | golgin B1 | -0.0134057 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0130847 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0130436 |
| SETD5 | SET domain containing 5 | -0.0126066 |
| SMC5 | structural maintenance of chromosomes 5 | -0.012379 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0122193 |
| RPS27A | ribosomal protein S27a | -0.0117832 |
| RPS19 | ribosomal protein S19 | -0.011595 |
| RPL11 | ribosomal protein L11 | -0.0111848 |
