| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0584587 |
| TMSB4X | thymosin beta 4, X-linked | 0.0547149 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0462437 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0434647 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0425771 |
| AHNAK | AHNAK nucleoprotein | 0.0424062 |
| ZNF292 | zinc finger protein 292 | 0.0386943 |
| RTN4 | reticulon 4 | 0.0374772 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0374705 |
| JMJD1C | jumonji domain containing 1C | 0.0363519 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0362049 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0355007 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.032938 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0322868 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0310394 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0270213 |
| PKM | pyruvate kinase, muscle | 0.0263617 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0260121 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0253721 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0245577 |
| VMP1 | vacuole membrane protein 1 | 0.0244596 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0239812 |
| NCKAP1 | NCK-associated protein 1 | 0.0231223 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0230794 |
| QKI | QKI, KH domain containing, RNA binding | 0.022798 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0227677 |
| RLF | rearranged L-myc fusion | 0.0225791 |
| ANXA1 | annexin A1 | 0.0222737 |
| B2M | beta-2-microglobulin | 0.0214411 |
| DSCAM | Down syndrome cell adhesion molecule | 0.020728 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0204672 |
| FBXO11 | F-box protein 11 | 0.0200171 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0197706 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0191425 |
| S100A6 | S100 calcium binding protein A6 | 0.0189578 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0188268 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0187934 |
| CCNL1 | cyclin L1 | 0.018097 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0180824 |
| PYGB | phosphorylase, glycogen; brain | 0.0178814 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0177226 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.017696 |
| YTHDC1 | YTH domain containing 1 | 0.0175265 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0173698 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0172361 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0162638 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162601 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.016222 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0157649 |
| HDAC9 | histone deacetylase 9 | 0.0157524 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0156266 |
| OSMR | oncostatin M receptor | 0.015612 |
| RHOA | ras homolog family member A | 0.0154 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0152758 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0151561 |
| APP | amyloid beta (A4) precursor protein | 0.0151058 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0149805 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0148846 |
| PDGFC | platelet derived growth factor C | 0.0148822 |
| SLMAP | sarcolemma associated protein | 0.014754 |
| MATR3 | matrin 3 | 0.0147456 |
| USP3 | ubiquitin specific peptidase 3 | 0.0144618 |
| RNF145 | ring finger protein 145 | 0.014455 |
| RHEB | Ras homolog enriched in brain | 0.0144277 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0143009 |
| OGA | O-GlcNAcase | 0.0142864 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0141442 |
| ZFR | zinc finger RNA binding protein | 0.013953 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0136991 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0136581 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0136149 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0133949 |
| EZR | ezrin | 0.0133817 |
| PDS5A | PDS5 cohesin associated factor A | 0.0133028 |
| SNX9 | sorting nexin 9 | 0.0132605 |
| COG5 | component of oligomeric golgi complex 5 | 0.0132083 |
| SPAG9 | sperm associated antigen 9 | 0.0132012 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0129887 |
| PLPP3 | phospholipid phosphatase 3 | 0.0128125 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0127702 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0127561 |
| NBAS | neuroblastoma amplified sequence | 0.0126271 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0126152 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0124909 |
| RBM33 | RNA binding motif protein 33 | 0.0124354 |
| UBC | ubiquitin C | 0.0124344 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0123196 |
| POU2F1 | POU class 2 homeobox 1 | 0.0123113 |
| COPA | coatomer protein complex, subunit alpha | 0.012283 |
| UBQLN1 | ubiquilin 1 | 0.0122308 |
| TFG | TRK-fused gene | 0.0122063 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0121756 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0121595 |
| ABHD12 | abhydrolase domain containing 12 | 0.0121475 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0121462 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0121079 |
| MEF2A | myocyte enhancer factor 2A | 0.0120973 |
| YAP1 | Yes-associated protein 1 | 0.0120947 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0120943 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0119915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.11461 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0893337 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0803095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0585121 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.054605 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0451045 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0439008 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.040943 |
| BMP10 | bone morphogenetic protein 10 | -0.0365374 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0325303 |
| PRELID2 | PRELI domain containing 2 | -0.0309607 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0298885 |
| NAV2 | neuron navigator 2 | -0.0277551 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0268425 |
| NBEA | neurobeachin | -0.0257261 |
| RPS6 | ribosomal protein S6 | -0.024538 |
| PTMA | prothymosin, alpha | -0.0241851 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0229178 |
| RPS8 | ribosomal protein S8 | -0.0227129 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0226676 |
| EVI5 | ecotropic viral integration site 5 | -0.0226599 |
| RPL9 | ribosomal protein L9 | -0.0222775 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0221225 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0217659 |
| DIAPH3 | diaphanous-related formin 3 | -0.0207771 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0202369 |
| FHIT | fragile histidine triad | -0.0201955 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0196505 |
| CENPF | centromere protein F, 350/400kDa | -0.0196074 |
| GSE1 | Gse1 coiled-coil protein | -0.0193927 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.018861 |
| MYOF | myoferlin | -0.0184593 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0180728 |
| NEBL | nebulette | -0.0178397 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0177126 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0175179 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0172625 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0169614 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0165395 |
| SBF2 | SET binding factor 2 | -0.0164902 |
| CENPE | centromere protein E, 312kDa | -0.0163501 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0161156 |
| RPS23 | ribosomal protein S23 | -0.0156898 |
| CD47 | CD47 molecule | -0.0156692 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0154744 |
| PFN1 | profilin 1 | -0.0151526 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0151112 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0149414 |
| DENND1A | DENN/MADD domain containing 1A | -0.0147984 |
| RPL23 | ribosomal protein L23 | -0.0147429 |
| GLI3 | GLI family zinc finger 3 | -0.0146605 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0146564 |
| ANKRD17 | ankyrin repeat domain 17 | -0.014529 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0142872 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0141758 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0141418 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0141059 |
| TJP1 | tight junction protein 1 | -0.0140542 |
| RPS13 | ribosomal protein S13 | -0.0139899 |
| RPS21 | ribosomal protein S21 | -0.0139761 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0137669 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0137283 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0135815 |
| GLI2 | GLI family zinc finger 2 | -0.0134788 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0134604 |
| MSI2 | musashi RNA-binding protein 2 | -0.0133444 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0132053 |
| RPL37A | ribosomal protein L37a | -0.0130456 |
| RPL26 | ribosomal protein L26 | -0.0129718 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0129328 |
| ONECUT2 | one cut homeobox 2 | -0.0127075 |
| RPL31 | ribosomal protein L31 | -0.0123463 |
| RPL32 | ribosomal protein L32 | -0.0123069 |
| ASPH | aspartate beta-hydroxylase | -0.0121668 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0119189 |
| HMGA1 | high mobility group AT-hook 1 | -0.0116074 |
| PDE7B | phosphodiesterase 7B | -0.0114606 |
| RPS12 | ribosomal protein S12 | -0.0114487 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0114394 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0114068 |
| RPL19 | ribosomal protein L19 | -0.0113056 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0112051 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0111561 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0110853 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0110694 |
| FNIP1 | folliculin interacting protein 1 | -0.0110611 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0109938 |
| CUX1 | cut-like homeobox 1 | -0.0109462 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0109157 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0108692 |
| MEIS2 | Meis homeobox 2 | -0.0106772 |
| TUBA1C | tubulin, alpha 1c | -0.0106314 |
| TPX2 | TPX2, microtubule-associated | -0.0105826 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0104944 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0104546 |
| RPL11 | ribosomal protein L11 | -0.0104357 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0103346 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0102734 |
| PRDX2 | peroxiredoxin 2 | -0.0102379 |
| RPL37 | ribosomal protein L37 | -0.0102289 |
