| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.115479 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.101134 |
| HDAC9 | histone deacetylase 9 | 0.0931321 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0837062 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0691402 |
| NAV2 | neuron navigator 2 | 0.0687203 |
| FNIP1 | folliculin interacting protein 1 | 0.0645096 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.06152 |
| INTS6 | integrator complex subunit 6 | 0.0599631 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0591187 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0536976 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0442809 |
| AHNAK | AHNAK nucleoprotein | 0.0415624 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0388205 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0350041 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.034347 |
| SQSTM1 | sequestosome 1 | 0.0335257 |
| ATXN1 | ataxin 1 | 0.033228 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0329924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.032921 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0312893 |
| ASPH | aspartate beta-hydroxylase | 0.0308367 |
| PCBP3 | poly(rC) binding protein 3 | 0.0307806 |
| DUSP10 | dual specificity phosphatase 10 | 0.0301666 |
| FMNL2 | formin-like 2 | 0.0301241 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0300248 |
| PRELID2 | PRELI domain containing 2 | 0.0297916 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0296759 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0291212 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0289749 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0288301 |
| PDE10A | phosphodiesterase 10A | 0.0287805 |
| HMGA2 | high mobility group AT-hook 2 | 0.0284757 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0269929 |
| VMP1 | vacuole membrane protein 1 | 0.0269434 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0259319 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0254633 |
| DST | dystonin | 0.0254002 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0252521 |
| MYOF | myoferlin | 0.0249015 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.02477 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0246376 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0245572 |
| RPL4 | ribosomal protein L4 | 0.0241417 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0240979 |
| VCL | vinculin | 0.0240715 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0240465 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0230783 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0227471 |
| CLTC | clathrin, heavy chain (Hc) | 0.0224417 |
| SMYD3 | SET and MYND domain containing 3 | 0.0223992 |
| PDLIM5 | PDZ and LIM domain 5 | 0.022357 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0221875 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0216674 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0216637 |
| RND3 | Rho family GTPase 3 | 0.0215858 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0214287 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0212697 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0211888 |
| BRD2 | bromodomain containing 2 | 0.0211112 |
| GOLGB1 | golgin B1 | 0.0207239 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205821 |
| EGFR | epidermal growth factor receptor | 0.0203866 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0203722 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0201839 |
| EFNA5 | ephrin-A5 | 0.0200573 |
| KYNU | kynureninase | 0.019955 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0198862 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198818 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0196305 |
| ARFGEF3 | ARFGEF family member 3 | 0.0196094 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0193293 |
| TLE4 | transducin-like enhancer of split 4 | 0.0188671 |
| COL5A1 | collagen, type V, alpha 1 | 0.0186067 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0185551 |
| GPC6 | glypican 6 | 0.0181643 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0176005 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0175801 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0174177 |
| USP53 | ubiquitin specific peptidase 53 | 0.0171641 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0170695 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0170287 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0169851 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0168908 |
| TMEM132D | transmembrane protein 132D | 0.0168708 |
| SNX14 | sorting nexin 14 | 0.0168579 |
| FNIP2 | folliculin interacting protein 2 | 0.0167898 |
| HLA-E | major histocompatibility complex, class I, E | 0.0165809 |
| UBAP2 | ubiquitin associated protein 2 | 0.0165747 |
| PHF3 | PHD finger protein 3 | 0.0163639 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0163636 |
| PRKCE | protein kinase C, epsilon | 0.0161572 |
| EXOC4 | exocyst complex component 4 | 0.0160981 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.016028 |
| ZNF608 | zinc finger protein 608 | 0.0160179 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0158501 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0158094 |
| CD109 | CD109 molecule | 0.0157987 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0157854 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0157537 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.357881 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.158596 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.153728 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.145707 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.145048 |
| HLA-B | major histocompatibility complex, class I, B | -0.127646 |
| TMSB10 | thymosin beta 10 | -0.127373 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.118634 |
| FN1 | fibronectin 1 | -0.116939 |
| FTL | ferritin, light polypeptide | -0.10659 |
| RPS6 | ribosomal protein S6 | -0.0843502 |
| PTMA | prothymosin, alpha | -0.0795876 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0795257 |
| NDRG1 | N-myc downstream regulated 1 | -0.0787546 |
| VEGFA | vascular endothelial growth factor A | -0.0757731 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0738845 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0731081 |
| TPM4 | tropomyosin 4 | -0.0730643 |
| EGR1 | early growth response 1 | -0.0691514 |
| RPL35A | ribosomal protein L35a | -0.068955 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.062641 |
| RPL23 | ribosomal protein L23 | -0.062321 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0622903 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0571536 |
| C3 | complement component 3 | -0.0559968 |
| B2M | beta-2-microglobulin | -0.0552741 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0542982 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0527695 |
| HLA-A | major histocompatibility complex, class I, A | -0.0506909 |
| MT2A | metallothionein 2A | -0.0498526 |
| RTN4 | reticulon 4 | -0.0471321 |
| RPS19 | ribosomal protein S19 | -0.0466764 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.045947 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0458028 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0454581 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0441983 |
| VCAN | versican | -0.0436086 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0431436 |
| GNAS | GNAS complex locus | -0.0427439 |
| GLIS3 | GLIS family zinc finger 3 | -0.0425326 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0412129 |
| RPLP2 | ribosomal protein, large, P2 | -0.0408495 |
| HMGA1 | high mobility group AT-hook 1 | -0.0405576 |
| RPLP1 | ribosomal protein, large, P1 | -0.0404083 |
| CTSD | cathepsin D | -0.0401893 |
| ADM | adrenomedullin | -0.0401621 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0399751 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0399689 |
| PGK1 | phosphoglycerate kinase 1 | -0.0396483 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0395392 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0386395 |
| IER3 | immediate early response 3 | -0.0383149 |
| ACTG1 | actin gamma 1 | -0.0382736 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0382628 |
| RPS23 | ribosomal protein S23 | -0.0382237 |
| COL1A1 | collagen, type I, alpha 1 | -0.0380318 |
| FRMD4A | FERM domain containing 4A | -0.037906 |
| COL1A2 | collagen, type I, alpha 2 | -0.0371222 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0349211 |
| S100A9 | S100 calcium binding protein A9 | -0.034855 |
| RPL36A | ribosomal protein L36a | -0.0347941 |
| RNF213 | ring finger protein 213 | -0.0342856 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0342441 |
| PCBP2 | poly(rC) binding protein 2 | -0.0337445 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0335135 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0327594 |
| CLMP | CXADR-like membrane protein | -0.0322159 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0320541 |
| RPL37A | ribosomal protein L37a | -0.0320452 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0315831 |
| RPS21 | ribosomal protein S21 | -0.0311735 |
| RPS14 | ribosomal protein S14 | -0.0311707 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305601 |
| ARF4 | ADP-ribosylation factor 4 | -0.0302868 |
| RAI14 | retinoic acid induced 14 | -0.0302238 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0301493 |
| RPS8 | ribosomal protein S8 | -0.0296944 |
| POTEF | POTE ankyrin domain family, member F | -0.0295228 |
| CCNL1 | cyclin L1 | -0.0294002 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293916 |
| RPL36 | ribosomal protein L36 | -0.0293897 |
| ATP13A3 | ATPase type 13A3 | -0.0293003 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.02922 |
| IL6 | interleukin 6 | -0.0287712 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0287596 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0284672 |
| TAPBP | TAP binding protein (tapasin) | -0.0281414 |
| TMEM41B | transmembrane protein 41B | -0.0277317 |
| RPS24 | ribosomal protein S24 | -0.0276291 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.027544 |
| KRT19 | keratin 19, type I | -0.0271182 |
| ASTN2 | astrotactin 2 | -0.0269913 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.026972 |
| RPL31 | ribosomal protein L31 | -0.0269413 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0267064 |
| RPS13 | ribosomal protein S13 | -0.0266449 |
| CADM1 | cell adhesion molecule 1 | -0.0266049 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0264922 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0262744 |
| IER2 | immediate early response 2 | -0.0259656 |
