| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0719982 |
| EGFR | epidermal growth factor receptor | 0.0693758 |
| CDH13 | cadherin 13 | 0.067575 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0646067 |
| EFNA5 | ephrin-A5 | 0.0599164 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0576797 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0571055 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0534049 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0491935 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0429465 |
| RAI14 | retinoic acid induced 14 | 0.0426197 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0422222 |
| COL5A1 | collagen, type V, alpha 1 | 0.040489 |
| NRXN3 | neurexin 3 | 0.0396384 |
| GLIS3 | GLIS family zinc finger 3 | 0.0392736 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0387875 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0365635 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0362087 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0350139 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0349788 |
| INTS6 | integrator complex subunit 6 | 0.0339623 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0335396 |
| COG6 | component of oligomeric golgi complex 6 | 0.0334683 |
| HMGA2 | high mobility group AT-hook 2 | 0.0330666 |
| KYNU | kynureninase | 0.0328051 |
| ZNF638 | zinc finger protein 638 | 0.0320519 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0314357 |
| MAP4 | microtubule-associated protein 4 | 0.0314007 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0309694 |
| RUNX1 | runt-related transcription factor 1 | 0.0305611 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0299552 |
| RAD51B | RAD51 paralog B | 0.0299405 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0299185 |
| PARD3 | par-3 family cell polarity regulator | 0.0297204 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0296102 |
| EXOC4 | exocyst complex component 4 | 0.0292652 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0290248 |
| TPM1 | tropomyosin 1 (alpha) | 0.0283144 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.028221 |
| VCL | vinculin | 0.0273858 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0271517 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0268282 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0265216 |
| PRKCA | protein kinase C, alpha | 0.0264885 |
| NBEAL1 | neurobeachin-like 1 | 0.0264284 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0264249 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0260557 |
| GOLGB1 | golgin B1 | 0.025993 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0257154 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0255022 |
| FAM13B | family with sequence similarity 13, member B | 0.0253782 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0248809 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0246782 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.024461 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.02429 |
| TENM3 | teneurin transmembrane protein 3 | 0.0241526 |
| SP100 | SP100 nuclear antigen | 0.0241485 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0241083 |
| AK4 | adenylate kinase 4 | 0.0240569 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0235196 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.023269 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0232665 |
| SQSTM1 | sequestosome 1 | 0.0231752 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0230725 |
| PTGES2 | prostaglandin E synthase 2 | 0.0230598 |
| FHIT | fragile histidine triad | 0.0229834 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0227629 |
| AHR | aryl hydrocarbon receptor | 0.0221395 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0221376 |
| FBXO11 | F-box protein 11 | 0.0220108 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0219515 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.02175 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0217408 |
| SBF2 | SET binding factor 2 | 0.0216557 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0215591 |
| CUX1 | cut-like homeobox 1 | 0.0213901 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0213722 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0212444 |
| NAV1 | neuron navigator 1 | 0.0209946 |
| MORF4L2 | mortality factor 4 like 2 | 0.0207865 |
| WWOX | WW domain containing oxidoreductase | 0.0207482 |
| FNIP1 | folliculin interacting protein 1 | 0.0206876 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0205122 |
| DST | dystonin | 0.0204102 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.020361 |
| WDR26 | WD repeat domain 26 | 0.0203401 |
| YAP1 | Yes-associated protein 1 | 0.0202962 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0202576 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0202031 |
| VEGFA | vascular endothelial growth factor A | 0.0201205 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0200569 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0199482 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0199142 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0198958 |
| AFF3 | AF4/FMR2 family, member 3 | 0.019854 |
| JPH2 | junctophilin 2 | 0.0197818 |
| TMEM165 | transmembrane protein 165 | 0.0196238 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0194461 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0194113 |
| RHBDD1 | rhomboid domain containing 1 | 0.0193961 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244473 |
| TMSB10 | thymosin beta 10 | -0.209438 |
| MT2A | metallothionein 2A | -0.161937 |
| VIM | vimentin | -0.15057 |
| COL6A3 | collagen, type VI, alpha 3 | -0.106696 |
| FN1 | fibronectin 1 | -0.0835845 |
| COL1A2 | collagen, type I, alpha 2 | -0.0833398 |
| B2M | beta-2-microglobulin | -0.0811599 |
| PTMA | prothymosin, alpha | -0.0805863 |
| SDC4 | syndecan 4 | -0.0805794 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0799904 |
| NDRG1 | N-myc downstream regulated 1 | -0.0697041 |
| UBC | ubiquitin C | -0.0649797 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0507938 |
| TXNIP | thioredoxin interacting protein | -0.0483335 |
| RTN4 | reticulon 4 | -0.0477014 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0472218 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0468098 |
| ENO1 | enolase 1, (alpha) | -0.0455294 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0446664 |
| SEPTIN7 | septin 7 | -0.0441581 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0438136 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0423668 |
| ARRDC3 | arrestin domain containing 3 | -0.0423592 |
| COL1A1 | collagen, type I, alpha 1 | -0.0420101 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.04115 |
| WTAP | Wilms tumor 1 associated protein | -0.041008 |
| SPAG9 | sperm associated antigen 9 | -0.0406935 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0400833 |
| MT1X | metallothionein 1X | -0.039708 |
| ANXA5 | annexin A5 | -0.0385813 |
| IL6 | interleukin 6 | -0.0376844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0376533 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.037421 |
| FTL | ferritin, light polypeptide | -0.036669 |
| JUN | jun proto-oncogene | -0.0365295 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0364581 |
| LDHA | lactate dehydrogenase A | -0.0361183 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358839 |
| H3-3B | H3.3 histone B | -0.0354357 |
| HLA-C | major histocompatibility complex, class I, C | -0.0348981 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0339734 |
| ANXA2 | annexin A2 | -0.0339349 |
| S100A10 | S100 calcium binding protein A10 | -0.0336488 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0334201 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.03257 |
| FLNA | filamin A, alpha | -0.031888 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316917 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0316512 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0315205 |
| COL5A2 | collagen, type V, alpha 2 | -0.0312572 |
| MATR3 | matrin 3 | -0.0311425 |
| RPL23 | ribosomal protein L23 | -0.0310275 |
| CENPF | centromere protein F, 350/400kDa | -0.0307884 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307666 |
| CALU | calumenin | -0.0304627 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0303897 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0297611 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0297566 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0294746 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0290257 |
| AHNAK | AHNAK nucleoprotein | -0.0289253 |
| ITM2B | integral membrane protein 2B | -0.0286364 |
| CCNI | cyclin I | -0.0285628 |
| BSG | basigin (Ok blood group) | -0.0285135 |
| POTEF | POTE ankyrin domain family, member F | -0.0282668 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0281172 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.027799 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0273888 |
| FLNB | filamin B, beta | -0.0269827 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0268684 |
| RAI1 | retinoic acid induced 1 | -0.026399 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0262709 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0260709 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0258466 |
| LOX | lysyl oxidase | -0.0257234 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0254552 |
| S100A9 | S100 calcium binding protein A9 | -0.0252838 |
| TPM2 | tropomyosin 2 (beta) | -0.0252417 |
| TAGLN2 | transgelin 2 | -0.0248884 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0248518 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0241466 |
| GANAB | glucosidase, alpha; neutral AB | -0.0241085 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0238978 |
| LMNA | lamin A/C | -0.0234747 |
| CD44 | CD44 molecule (Indian blood group) | -0.0234611 |
| RPL5 | ribosomal protein L5 | -0.0230223 |
| S100A6 | S100 calcium binding protein A6 | -0.0225683 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0224753 |
| TPM4 | tropomyosin 4 | -0.0224317 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0224228 |
| RPL37A | ribosomal protein L37a | -0.0223705 |
| RPL15 | ribosomal protein L15 | -0.022361 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0221247 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0219173 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.021735 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0216296 |
| C1D | C1D nuclear receptor corepressor | -0.0215037 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0213808 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0213212 |
