| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sinomenine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sinomenine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.125607 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0851098 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0543636 |
| JMJD1C | jumonji domain containing 1C | 0.0529514 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0524991 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0524973 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0524449 |
| SVIL | supervillin | 0.0510108 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0485428 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0453532 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0451396 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0437632 |
| ANGPTL4 | angiopoietin-like 4 | 0.0429765 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0423054 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0409629 |
| ANXA2 | annexin A2 | 0.0406966 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0389275 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0386334 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0377353 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0374012 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0369773 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0369552 |
| RSF1 | remodeling and spacing factor 1 | 0.0363354 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0360893 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0358183 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0344166 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0332902 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.032733 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0324444 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0314547 |
| QKI | QKI, KH domain containing, RNA binding | 0.0314545 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.030931 |
| BSG | basigin (Ok blood group) | 0.0307312 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.030447 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0303819 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.029992 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0299542 |
| ANXA1 | annexin A1 | 0.0299439 |
| PNN | pinin, desmosome associated protein | 0.0299404 |
| ZNF254 | zinc finger protein 254 | 0.0295963 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0295804 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0292906 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0291085 |
| TXNRD1 | thioredoxin reductase 1 | 0.0287826 |
| CUL1 | cullin 1 | 0.0285825 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0284125 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0283746 |
| CCNH | cyclin H | 0.0281317 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0280186 |
| SNX9 | sorting nexin 9 | 0.0277136 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0267479 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0266373 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.026593 |
| DNM1L | dynamin 1-like | 0.0265564 |
| DTNB | dystrobrevin, beta | 0.0263687 |
| SLMAP | sarcolemma associated protein | 0.0261718 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0261539 |
| VRK2 | vaccinia related kinase 2 | 0.026107 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0260594 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0260053 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0259948 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0259939 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0259306 |
| CCDC146 | coiled-coil domain containing 146 | 0.0255805 |
| ZNF638 | zinc finger protein 638 | 0.025327 |
| ITGB5 | integrin, beta 5 | 0.0253259 |
| CFH | complement factor H | 0.0253084 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0251153 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0250811 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0248707 |
| FAM13A | family with sequence similarity 13, member A | 0.0246269 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0245283 |
| AXL | AXL receptor tyrosine kinase | 0.024309 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0241469 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0239584 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0239436 |
| RHBDD1 | rhomboid domain containing 1 | 0.0238945 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.023605 |
| RPLP1 | ribosomal protein, large, P1 | 0.0232636 |
| TET3 | tet methylcytosine dioxygenase 3 | 0.0231592 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0231222 |
| UBXN4 | UBX domain protein 4 | 0.0230991 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0230555 |
| SLC35E3 | solute carrier family 35, member E3 | 0.0229601 |
| TMEM263 | transmembrane protein 263 | 0.0229503 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0229108 |
| LEPROT | leptin receptor overlapping transcript | 0.0228998 |
| FMNL2 | formin-like 2 | 0.0228771 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0227758 |
| PHF3 | PHD finger protein 3 | 0.0225391 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0225234 |
| WWOX | WW domain containing oxidoreductase | 0.0224956 |
| RUFY1 | RUN and FYVE domain containing 1 | 0.0224906 |
| TUBB | tubulin, beta class I | 0.022487 |
| CDK7 | cyclin-dependent kinase 7 | 0.0224651 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0222589 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0222067 |
| RNF145 | ring finger protein 145 | 0.0221505 |
| STXBP1 | syntaxin binding protein 1 | 0.0218782 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0218725 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163607 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0768469 |
| CD44 | CD44 molecule (Indian blood group) | -0.0721556 |
| PCBP2 | poly(rC) binding protein 2 | -0.0714757 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0685821 |
| PKM | pyruvate kinase, muscle | -0.0683291 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0596248 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0568989 |
| UBC | ubiquitin C | -0.0555855 |
| PTMA | prothymosin, alpha | -0.0542178 |
| RPL23 | ribosomal protein L23 | -0.0511175 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0501497 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0497126 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0489615 |
| VIM | vimentin | -0.0484973 |
| PRELID2 | PRELI domain containing 2 | -0.0474634 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0463561 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.045906 |
| ZNF292 | zinc finger protein 292 | -0.0456642 |
| MCL1 | myeloid cell leukemia 1 | -0.0449696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0448087 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0434134 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0415067 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0414234 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0413124 |
| NUP58 | nucleoporin 58 | -0.0413067 |
| RPS13 | ribosomal protein S13 | -0.0402795 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0398996 |
| CEP250 | centrosomal protein 250kDa | -0.0396351 |
| CREBRF | CREB3 regulatory factor | -0.0392935 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.039264 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.039219 |
| RPS27A | ribosomal protein S27a | -0.0391315 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0390466 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0389329 |
| POTEF | POTE ankyrin domain family, member F | -0.0388815 |
| USP22 | ubiquitin specific peptidase 22 | -0.0380858 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0380752 |
| ATP13A3 | ATPase type 13A3 | -0.0379506 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.037926 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0373557 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0364932 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0362757 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0361306 |
| EGR1 | early growth response 1 | -0.0356725 |
| S100A9 | S100 calcium binding protein A9 | -0.0355669 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0355439 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0351398 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0351191 |
| RPS6 | ribosomal protein S6 | -0.0350557 |
| CUL5 | cullin 5 | -0.0349981 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | -0.0347405 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0346109 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0345941 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0345131 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0343722 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0342723 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0341638 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0338557 |
| TMSB10 | thymosin beta 10 | -0.0338007 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0337297 |
| RPL37 | ribosomal protein L37 | -0.0332465 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0331272 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.033072 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0330653 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0330438 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0326484 |
| HDAC9 | histone deacetylase 9 | -0.0325793 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0323683 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0318801 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.031877 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0312757 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0311189 |
| FUS | FUS RNA binding protein | -0.0309438 |
| DIAPH3 | diaphanous-related formin 3 | -0.030933 |
| RAB10 | RAB10, member RAS oncogene family | -0.0306333 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0305765 |
| BRD4 | bromodomain containing 4 | -0.0305287 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0302813 |
| ENO1 | enolase 1, (alpha) | -0.0302622 |
| HMGA2 | high mobility group AT-hook 2 | -0.0299275 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0299155 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0297875 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0295139 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0293738 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0292848 |
| PRSS23 | protease, serine, 23 | -0.0292469 |
| ERGIC3 | ERGIC and golgi 3 | -0.0291785 |
| OSMR | oncostatin M receptor | -0.0291223 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0291172 |
| ETV1 | ets variant 1 | -0.0290796 |
| JUN | jun proto-oncogene | -0.0290656 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0289458 |
| CALU | calumenin | -0.0288318 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0288164 |
| DST | dystonin | -0.0286715 |
| FNIP1 | folliculin interacting protein 1 | -0.0282634 |
| USP15 | ubiquitin specific peptidase 15 | -0.0280922 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.0276828 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0276372 |
