Sinusitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. (Human Disease Ontology, DOID_0050127)
External Link https://www.disgenet.org/browser/0/1/0/C0037199
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Genes

94 genes associated with the disease Sinusitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACR acrosin
ADA adenosine deaminase
AP5B1 adaptor-related protein complex 5, beta 1 subunit
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASCC1 activating signal cointegrator 1 complex subunit 1
ATM ATM serine/threonine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLM Bloom syndrome, RecQ helicase-like
BLNK B-cell linker
BTK Bruton agammaglobulinemia tyrosine kinase
C17ORF62 chromosome 17 open reading frame 62
CCDC40 coiled-coil domain containing 40
CCL11 chemokine (C-C motif) ligand 11
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CD40 CD40 molecule, TNF receptor superfamily member 5
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CFI complement factor I
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIITA class II, major histocompatibility complex, transactivator
CLEC4D C-type lectin domain family 4, member D
CLU clusterin
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DICER1 dicer 1, ribonuclease type III
DNAAF1 dynein, axonemal, assembly factor 1
DNAAF3 dynein, axonemal, assembly factor 3
DNAI1 dynein, axonemal, intermediate chain 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EPX eosinophil peroxidase
FMR1 fragile X mental retardation 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL13 interleukin 13
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL22 interleukin 22
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
IRF8 interferon regulatory factor 8
LRRC8A leucine rich repeat containing 8 family, member A
LTC4S leukotriene C4 synthase
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME8 NME/NM23 family member 8
PDPN podoplanin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP prolactin-induced protein
PNP purine nucleoside phosphorylase
POSTN periostin, osteoblast specific factor
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRTN3 proteinase 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAG2 recombination activating gene 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RFXANK regulatory factor X-associated ankyrin-containing protein
RFXAP regulatory factor X-associated protein
RSPH4A radial spoke head 4 homolog A (Chlamydomonas)
RUNX2 runt-related transcription factor 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SMOX spermine oxidase
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SYT1 synaptotagmin I
TCF3 transcription factor 3
TNF tumor necrosis factor
VEGFA vascular endothelial growth factor A
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
WNK1 WNK lysine deficient protein kinase 1