| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.110877 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0988201 |
| VCAN | versican | 0.0934907 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0932576 |
| NDRG1 | N-myc downstream regulated 1 | 0.0852043 |
| LDHA | lactate dehydrogenase A | 0.0841284 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0816755 |
| ASPH | aspartate beta-hydroxylase | 0.0786546 |
| FLNB | filamin B, beta | 0.0736574 |
| ITGA6 | integrin, alpha 6 | 0.073432 |
| FAM107B | family with sequence similarity 107, member B | 0.0697027 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0688583 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0674599 |
| SDC4 | syndecan 4 | 0.0666086 |
| MYOF | myoferlin | 0.0623752 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0612289 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0611395 |
| EFNA5 | ephrin-A5 | 0.060929 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0607058 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0594483 |
| PRELID2 | PRELI domain containing 2 | 0.0578653 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0563275 |
| OGA | O-GlcNAcase | 0.0563175 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0555043 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0553965 |
| EMP1 | epithelial membrane protein 1 | 0.0551441 |
| PLEC | plectin | 0.0531803 |
| S100A10 | S100 calcium binding protein A10 | 0.0530498 |
| ANXA2 | annexin A2 | 0.052728 |
| EZR | ezrin | 0.0518253 |
| SMAD3 | SMAD family member 3 | 0.0509882 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0501859 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0487197 |
| DSG2 | desmoglein 2 | 0.0486083 |
| FAT1 | FAT atypical cadherin 1 | 0.0476307 |
| PGK1 | phosphoglycerate kinase 1 | 0.0474918 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0473706 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0471743 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0461059 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.04604 |
| ITGB4 | integrin, beta 4 | 0.0439883 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0418922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.040163 |
| LMO7 | LIM domain 7 | 0.0397406 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0387685 |
| PTMA | prothymosin, alpha | 0.0386573 |
| ANLN | anillin, actin binding protein | 0.0383417 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0368358 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0364571 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0358781 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0357935 |
| ENO1 | enolase 1, (alpha) | 0.035478 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0353272 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0352219 |
| NEK7 | NIMA-related kinase 7 | 0.034873 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0342258 |
| JMJD1C | jumonji domain containing 1C | 0.0331945 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0328079 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0326812 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0323768 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0319997 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0318117 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0315604 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0311715 |
| ANXA11 | annexin A11 | 0.0311015 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0309284 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0308251 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0305657 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0304083 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0297306 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0296093 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0293811 |
| EGFR | epidermal growth factor receptor | 0.0292292 |
| MUC17 | mucin 17, cell surface associated | 0.0290829 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0288882 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0286215 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0284848 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0284788 |
| MED13L | mediator complex subunit 13-like | 0.0282865 |
| STK39 | serine threonine kinase 39 | 0.0282666 |
| DST | dystonin | 0.0281195 |
| CD9 | CD9 molecule | 0.0276237 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0275114 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0273453 |
| ERBIN | erbb2 interacting protein | 0.0273313 |
| CANX | calnexin | 0.0271369 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0270185 |
| NPTN | neuroplastin | 0.0268764 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0264974 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0257764 |
| SQSTM1 | sequestosome 1 | 0.0256858 |
| ITGAV | integrin, alpha V | 0.0255029 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0254019 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0250536 |
| HPCAL1 | hippocalcin-like 1 | 0.0248732 |
| ARRDC3 | arrestin domain containing 3 | 0.024745 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.02474 |
| FAM13A | family with sequence similarity 13, member A | 0.0246927 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0246835 |
| EHBP1 | EH domain binding protein 1 | 0.0246378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.139828 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0964467 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0904739 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0751562 |
| LAMB3 | laminin, beta 3 | -0.0624105 |
| KLK10 | kallikrein-related peptidase 10 | -0.0614097 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.057736 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0497089 |
| CLMP | CXADR-like membrane protein | -0.0460446 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0418087 |
| TXNRD1 | thioredoxin reductase 1 | -0.0405239 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0403678 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0386293 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0383928 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0381948 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0369863 |
| MXD1 | MAX dimerization protein 1 | -0.03683 |
| UPP1 | uridine phosphorylase 1 | -0.0357462 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0339302 |
| AK1 | adenylate kinase 1 | -0.0318359 |
| PMM2 | phosphomannomutase 2 | -0.0315295 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0290025 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0289144 |
| HMGA1 | high mobility group AT-hook 1 | -0.0279467 |
| FTL | ferritin, light polypeptide | -0.0268256 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0266492 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0266152 |
| HM13 | histocompatibility (minor) 13 | -0.0263016 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0255751 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0253935 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0252926 |
| HDAC9 | histone deacetylase 9 | -0.0249404 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0243592 |
| TPM4 | tropomyosin 4 | -0.0241348 |
| RPS21 | ribosomal protein S21 | -0.0240899 |
| DENND2C | DENN/MADD domain containing 2C | -0.0240776 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0238647 |
| RASAL2 | RAS protein activator like 2 | -0.0238352 |
| TGFA | transforming growth factor, alpha | -0.023472 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0226571 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0222353 |
| MIDN | midnolin | -0.0221695 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0219103 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0218635 |
| EGR1 | early growth response 1 | -0.0218428 |
| PARD3 | par-3 family cell polarity regulator | -0.0217377 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0215898 |
| UBAP2 | ubiquitin associated protein 2 | -0.0214786 |
| BMP6 | bone morphogenetic protein 6 | -0.0208355 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0204695 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0203542 |
| RPS13 | ribosomal protein S13 | -0.0202194 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0198227 |
| TXNIP | thioredoxin interacting protein | -0.0198057 |
| OSMR | oncostatin M receptor | -0.019682 |
| FBXO11 | F-box protein 11 | -0.0192521 |
| ABHD3 | abhydrolase domain containing 3 | -0.019237 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0189573 |
| MSN | moesin | -0.0185126 |
| FMNL2 | formin-like 2 | -0.0183268 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0182553 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0180612 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0179798 |
| RRBP1 | ribosome binding protein 1 | -0.0177433 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0177255 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0175728 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0171136 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0164726 |
| ARF4 | ADP-ribosylation factor 4 | -0.016431 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0162802 |
| RBM25 | RNA binding motif protein 25 | -0.0162286 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0159924 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0158968 |
| ZNF83 | zinc finger protein 83 | -0.0158736 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0158349 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | -0.01579 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.015479 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0154489 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0154486 |
| GOLGA4 | golgin A4 | -0.0154375 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0153168 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0151585 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0150482 |
| EVI5 | ecotropic viral integration site 5 | -0.0149823 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0148469 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0146501 |
| NUP98 | nucleoporin 98kDa | -0.0146239 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0144698 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.0144678 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0144661 |
| LAMC2 | laminin, gamma 2 | -0.0143964 |
| PRSS3 | protease, serine, 3 | -0.014369 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0143172 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0142675 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.014175 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.014096 |
| SCFD2 | sec1 family domain containing 2 | -0.0140929 |
| SNX9 | sorting nexin 9 | -0.0140834 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0140219 |
| DIAPH1 | diaphanous-related formin 1 | -0.0138644 |
