| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0772334 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0427165 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0375576 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0341898 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0333543 |
| RNF43 | ring finger protein 43 | 0.0308734 |
| RUNX1 | runt-related transcription factor 1 | 0.030165 |
| PRELID2 | PRELI domain containing 2 | 0.0295611 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0288666 |
| COG6 | component of oligomeric golgi complex 6 | 0.0282677 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0281272 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0270831 |
| MLPH | melanophilin | 0.0262108 |
| LMO7 | LIM domain 7 | 0.0258944 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0252817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0247473 |
| FNIP1 | folliculin interacting protein 1 | 0.0246225 |
| RBM39 | RNA binding motif protein 39 | 0.0245973 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0245235 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0235957 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0231485 |
| SEC24D | SEC24 family member D | 0.0228588 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0226797 |
| OGA | O-GlcNAcase | 0.0217682 |
| SUCO | SUN domain containing ossification factor | 0.0215908 |
| PTEN | phosphatase and tensin homolog | 0.0211331 |
| UBL3 | ubiquitin-like 3 | 0.0209524 |
| EHF | ets homologous factor | 0.0205794 |
| PHF3 | PHD finger protein 3 | 0.0196044 |
| NEBL | nebulette | 0.0195025 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0194149 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0194024 |
| TC2N | tandem C2 domains, nuclear | 0.0190233 |
| TMEM39A | transmembrane protein 39A | 0.0189834 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0189295 |
| HELZ | helicase with zinc finger | 0.0187338 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0180084 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0176895 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0173479 |
| COPA | coatomer protein complex, subunit alpha | 0.0169403 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0165306 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0163611 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0162359 |
| MEIS2 | Meis homeobox 2 | 0.0159299 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0157176 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0153766 |
| ETNK1 | ethanolamine kinase 1 | 0.015347 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0152896 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0150215 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0148936 |
| HDLBP | high density lipoprotein binding protein | 0.0148037 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.014632 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0145635 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0144592 |
| USP3 | ubiquitin specific peptidase 3 | 0.0142512 |
| ARRDC3 | arrestin domain containing 3 | 0.0142295 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.014185 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0140398 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0139831 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.01381 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.013732 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0136253 |
| FRK | fyn-related Src family tyrosine kinase | 0.0134946 |
| GALK2 | galactokinase 2 | 0.0133724 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0133514 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0132742 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0132505 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0131845 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0131559 |
| RBM33 | RNA binding motif protein 33 | 0.0130149 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0129975 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0129448 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0128201 |
| AHNAK | AHNAK nucleoprotein | 0.012749 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.012739 |
| NBAS | neuroblastoma amplified sequence | 0.0127184 |
| GRAMD2B | GRAM domain containing 2B | 0.0127141 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0124495 |
| DMXL2 | Dmx-like 2 | 0.0123941 |
| TBPL1 | TBP-like 1 | 0.012347 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0123443 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0122057 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.012204 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0122004 |
| TMEM263 | transmembrane protein 263 | 0.0121847 |
| DSPP | dentin sialophosphoprotein | 0.0121711 |
| ATOSA | atos homolog A | 0.0121152 |
| TSC22D2 | TSC22 domain family, member 2 | 0.012092 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0119702 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.011945 |
| ANO6 | anoctamin 6 | 0.0119445 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0118988 |
| LNX2 | ligand of numb-protein X 2 | 0.0118951 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0117564 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0116439 |
| CANX | calnexin | 0.0116332 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0116029 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0116005 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.011565 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0114713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.216732 |
| LCN2 | lipocalin 2 | -0.180324 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.173621 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.138508 |
| PTMA | prothymosin, alpha | -0.134856 |
| LYZ | lysozyme | -0.11492 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.102376 |
| HLA-B | major histocompatibility complex, class I, B | -0.0916391 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0857325 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0743717 |
| RNF213 | ring finger protein 213 | -0.0741992 |
| TMSB10 | thymosin beta 10 | -0.0729574 |
| FTL | ferritin, light polypeptide | -0.0714794 |
| RPL35A | ribosomal protein L35a | -0.0687872 |
| SP100 | SP100 nuclear antigen | -0.0675059 |
| MX2 | MX dynamin-like GTPase 2 | -0.0654155 |
| RPS6 | ribosomal protein S6 | -0.0633517 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.062017 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0609837 |
| EGR1 | early growth response 1 | -0.0601418 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0591268 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.058458 |
| MX1 | MX dynamin-like GTPase 1 | -0.058157 |
| RPL23 | ribosomal protein L23 | -0.0581542 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0561704 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0559786 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0538552 |
| RIGI | RNA sensor RIG-I | -0.0527105 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.050088 |
| XAF1 | XIAP associated factor 1 | -0.04961 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.04899 |
| TMC5 | transmembrane channel-like 5 | -0.0488761 |
| MT2A | metallothionein 2A | -0.0484353 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0480521 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0466116 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0465288 |
| NPSR1 | neuropeptide S receptor 1 | -0.0439581 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0434769 |
| PKM | pyruvate kinase, muscle | -0.0433712 |
| RPL19 | ribosomal protein L19 | -0.0431785 |
| RPS19 | ribosomal protein S19 | -0.0406702 |
| HLA-A | major histocompatibility complex, class I, A | -0.0406545 |
| RPL34 | ribosomal protein L34 | -0.0406049 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0403661 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0402989 |
| S100A6 | S100 calcium binding protein A6 | -0.0401519 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0400691 |
| RPL37A | ribosomal protein L37a | -0.0396933 |
| RPS8 | ribosomal protein S8 | -0.0396527 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0395389 |
| PMP22 | peripheral myelin protein 22 | -0.0392643 |
| CST3 | cystatin C | -0.0388709 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0387916 |
| RPLP1 | ribosomal protein, large, P1 | -0.0374768 |
| RPL11 | ribosomal protein L11 | -0.0369277 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0367951 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.036713 |
| MAP7 | microtubule-associated protein 7 | -0.0366133 |
| RPL26 | ribosomal protein L26 | -0.0351543 |
| AREG | amphiregulin | -0.0350288 |
| TPI1 | triosephosphate isomerase 1 | -0.0346677 |
| RPS3 | ribosomal protein S3 | -0.0345823 |
| SERF2 | small EDRK-rich factor 2 | -0.0344655 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0342929 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0341087 |
| JUN | jun proto-oncogene | -0.0338552 |
| RPL12 | ribosomal protein L12 | -0.0334326 |
| ACTG1 | actin gamma 1 | -0.0333746 |
| VCL | vinculin | -0.0325687 |
| RPS27 | ribosomal protein S27 | -0.0324857 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0322169 |
| RPL31 | ribosomal protein L31 | -0.0314546 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0314351 |
| PERP | PERP, TP53 apoptosis effector | -0.0311558 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0310434 |
| RPS12 | ribosomal protein S12 | -0.0305294 |
| ANXA2 | annexin A2 | -0.0296896 |
| KRT19 | keratin 19, type I | -0.0296777 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.029608 |
| ENO1 | enolase 1, (alpha) | -0.029561 |
| DSTN | destrin (actin depolymerizing factor) | -0.0295039 |
| ITGA6 | integrin, alpha 6 | -0.0294628 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292043 |
| HLA-C | major histocompatibility complex, class I, C | -0.02863 |
| S100A11 | S100 calcium binding protein A11 | -0.0284439 |
| RPS24 | ribosomal protein S24 | -0.028395 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280349 |
| POTEF | POTE ankyrin domain family, member F | -0.0280119 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0272706 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0270523 |
| S100A9 | S100 calcium binding protein A9 | -0.0270003 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0267721 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0267079 |
| EPCAM | epithelial cell adhesion molecule | -0.0266974 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0265252 |
| RPL37 | ribosomal protein L37 | -0.0262341 |
| RPL7A | ribosomal protein L7a | -0.0262095 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0261801 |
| HLA-E | major histocompatibility complex, class I, E | -0.0260935 |
| RPL9 | ribosomal protein L9 | -0.0259168 |
