| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.196713 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.18964 |
| FLNB | filamin B, beta | 0.126129 |
| MTSS1 | metastasis suppressor 1 | 0.124641 |
| DPYD | dihydropyrimidine dehydrogenase | 0.123666 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.118665 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.108494 |
| SLC35F3 | solute carrier family 35, member F3 | 0.106123 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.105271 |
| LMO7 | LIM domain 7 | 0.0988082 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0862111 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.08453 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0806505 |
| PODXL | podocalyxin-like | 0.0781518 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0771115 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0728794 |
| AHNAK | AHNAK nucleoprotein | 0.0726088 |
| MYOF | myoferlin | 0.0725978 |
| ASPH | aspartate beta-hydroxylase | 0.0703357 |
| PLEC | plectin | 0.0688432 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0653828 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0642582 |
| SULF1 | sulfatase 1 | 0.062252 |
| ITGA6 | integrin, alpha 6 | 0.0619675 |
| LDHA | lactate dehydrogenase A | 0.0618104 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0590213 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0584423 |
| MEF2A | myocyte enhancer factor 2A | 0.0581478 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0559 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0544843 |
| PTK2 | protein tyrosine kinase 2 | 0.0544837 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0528355 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.052611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.052224 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0521394 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0507243 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0506276 |
| NDRG1 | N-myc downstream regulated 1 | 0.0504548 |
| PLS3 | plastin 3 | 0.0501512 |
| RAD51B | RAD51 paralog B | 0.049038 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.048709 |
| MECOM | MDS1 and EVI1 complex locus | 0.0481552 |
| RIGI | RNA sensor RIG-I | 0.0470627 |
| MSN | moesin | 0.0461585 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0449284 |
| ENO1 | enolase 1, (alpha) | 0.0448493 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0437216 |
| TGM2 | transglutaminase 2 | 0.0436714 |
| EFNA5 | ephrin-A5 | 0.0435599 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0432551 |
| RASAL2 | RAS protein activator like 2 | 0.0431033 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0422715 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.042065 |
| SMYD3 | SET and MYND domain containing 3 | 0.042023 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0419427 |
| HMGA2 | high mobility group AT-hook 2 | 0.0412917 |
| MYO10 | myosin X | 0.0410092 |
| CDK6 | cyclin-dependent kinase 6 | 0.0402294 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0399705 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0395159 |
| AMOTL1 | angiomotin like 1 | 0.039505 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0389093 |
| MCL1 | myeloid cell leukemia 1 | 0.0382807 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0377539 |
| UTRN | utrophin | 0.037391 |
| SULF2 | sulfatase 2 | 0.0371925 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0370924 |
| RAI14 | retinoic acid induced 14 | 0.0369031 |
| PRELID2 | PRELI domain containing 2 | 0.0365713 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0358176 |
| DST | dystonin | 0.0356846 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0353145 |
| CMIP | c-Maf inducing protein | 0.0352703 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0351212 |
| EXOC4 | exocyst complex component 4 | 0.0350341 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0349838 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0348273 |
| FNIP1 | folliculin interacting protein 1 | 0.0346089 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0344524 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0343746 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0338061 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0336011 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0333993 |
| CLIC4 | chloride intracellular channel 4 | 0.0333268 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.032935 |
| LAMC2 | laminin, gamma 2 | 0.032777 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0326222 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0322547 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0320033 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0318413 |
| EGFR | epidermal growth factor receptor | 0.0317659 |
| NEK7 | NIMA-related kinase 7 | 0.0314934 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0312543 |
| INTS6 | integrator complex subunit 6 | 0.0312132 |
| FOXO1 | forkhead box O1 | 0.0310453 |
| RNF217 | ring finger protein 217 | 0.0308044 |
| PGK1 | phosphoglycerate kinase 1 | 0.030417 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0302342 |
| DGKH | diacylglycerol kinase, eta | 0.0300569 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0295959 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0887041 |
| TMSB10 | thymosin beta 10 | -0.0719468 |
| RPS21 | ribosomal protein S21 | -0.0663297 |
| MT2A | metallothionein 2A | -0.0634584 |
| PTMA | prothymosin, alpha | -0.0571613 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.05202 |
| RPS6 | ribosomal protein S6 | -0.0515649 |
| RPLP1 | ribosomal protein, large, P1 | -0.0511518 |
| RPLP2 | ribosomal protein, large, P2 | -0.049777 |
| RPS8 | ribosomal protein S8 | -0.049072 |
| TMSB4X | thymosin beta 4, X-linked | -0.0459113 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0407979 |
| S100A10 | S100 calcium binding protein A10 | -0.0386245 |
| RPL12 | ribosomal protein L12 | -0.0364682 |
| RPS19 | ribosomal protein S19 | -0.0350424 |
| RPL11 | ribosomal protein L11 | -0.0349789 |
| B2M | beta-2-microglobulin | -0.0341512 |
| LMNA | lamin A/C | -0.0339845 |
| RPS13 | ribosomal protein S13 | -0.0331652 |
| RPL35A | ribosomal protein L35a | -0.0307747 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306875 |
| RPL8 | ribosomal protein L8 | -0.0295636 |
| S100A6 | S100 calcium binding protein A6 | -0.0295474 |
| S100A2 | S100 calcium binding protein A2 | -0.0274555 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0274041 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0273719 |
| CLU | clusterin | -0.0273395 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0267489 |
| STC1 | stanniocalcin 1 | -0.0263952 |
| RPS27A | ribosomal protein S27a | -0.0259401 |
| RPL34 | ribosomal protein L34 | -0.0249324 |
| RPS12 | ribosomal protein S12 | -0.0247169 |
| GNAS | GNAS complex locus | -0.0245481 |
| RPL37 | ribosomal protein L37 | -0.0244376 |
| GOLGA4 | golgin A4 | -0.0243994 |
| RPL37A | ribosomal protein L37a | -0.0243014 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0241915 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0240496 |
| RPL19 | ribosomal protein L19 | -0.0240344 |
| HLA-B | major histocompatibility complex, class I, B | -0.023836 |
| RPL26 | ribosomal protein L26 | -0.0237958 |
| RPL30 | ribosomal protein L30 | -0.0233081 |
| RPL23 | ribosomal protein L23 | -0.0231848 |
| MT1X | metallothionein 1X | -0.0228769 |
| RPL35 | ribosomal protein L35 | -0.0219507 |
| RPL5 | ribosomal protein L5 | -0.0219353 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0219179 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0216782 |
| RPL27A | ribosomal protein L27a | -0.0216453 |
| FTL | ferritin, light polypeptide | -0.0215092 |
| S100A4 | S100 calcium binding protein A4 | -0.0213273 |
| RPS23 | ribosomal protein S23 | -0.0212613 |
| RPL32 | ribosomal protein L32 | -0.0209401 |
| RPS27 | ribosomal protein S27 | -0.0205352 |
| RPS24 | ribosomal protein S24 | -0.0204849 |
| DSTN | destrin (actin depolymerizing factor) | -0.0202776 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0197826 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0196781 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0196753 |
| RPL7A | ribosomal protein L7a | -0.0196555 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0195038 |
| RPS3 | ribosomal protein S3 | -0.0194322 |
| RACK1 | receptor for activated C kinase 1 | -0.0192148 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0188992 |
| IER3 | immediate early response 3 | -0.0188772 |
| RPL36A | ribosomal protein L36a | -0.0187689 |
| CAVIN1 | caveolae associated protein 1 | -0.0187414 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0186661 |
| RPLP0 | ribosomal protein, large, P0 | -0.0185655 |
| RPS14 | ribosomal protein S14 | -0.0183746 |
| RPL36 | ribosomal protein L36 | -0.0182871 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0181233 |
| RPS29 | ribosomal protein S29 | -0.0181054 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0177954 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0177303 |
| RPS4X | ribosomal protein S4, X-linked | -0.0176923 |
| H1-0 | H1.0 linker histone | -0.0174083 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0173356 |
| KRT17 | keratin 17, type I | -0.0173201 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0173074 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0172739 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0172334 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0171788 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0169592 |
| RPL9 | ribosomal protein L9 | -0.0168005 |
| RPS20 | ribosomal protein S20 | -0.01672 |
| RPL28 | ribosomal protein L28 | -0.0166434 |
| RPS25 | ribosomal protein S25 | -0.0165321 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0162992 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0161521 |
| RPL31 | ribosomal protein L31 | -0.015976 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0159016 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.015898 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0158174 |
| RPL18 | ribosomal protein L18 | -0.0157389 |
| YBX3 | Y box binding protein 3 | -0.0156534 |
| DUSP6 | dual specificity phosphatase 6 | -0.0153401 |
| SQLE | squalene epoxidase | -0.01467 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0146587 |
| RPL7 | ribosomal protein L7 | -0.0145364 |
