| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0946581 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0830674 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0700454 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0679328 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0671366 |
| ASPH | aspartate beta-hydroxylase | 0.0605165 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0603266 |
| FN1 | fibronectin 1 | 0.0598653 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0579148 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0511953 |
| AHNAK | AHNAK nucleoprotein | 0.0502656 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0473164 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0468768 |
| ANLN | anillin, actin binding protein | 0.0456956 |
| DAPK1 | death-associated protein kinase 1 | 0.045464 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0449728 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.044451 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0442781 |
| CD2AP | CD2-associated protein | 0.0431106 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0430402 |
| PGK1 | phosphoglycerate kinase 1 | 0.0420477 |
| CANX | calnexin | 0.0412206 |
| EZR | ezrin | 0.0405532 |
| RNF213 | ring finger protein 213 | 0.0402112 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0401482 |
| TPM4 | tropomyosin 4 | 0.0398702 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0393527 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0376576 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364819 |
| LDHA | lactate dehydrogenase A | 0.0339367 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0337653 |
| DST | dystonin | 0.0328181 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0325389 |
| DSG2 | desmoglein 2 | 0.032483 |
| MEF2A | myocyte enhancer factor 2A | 0.0304807 |
| PLAT | plasminogen activator, tissue | 0.0303378 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0284882 |
| RAD51B | RAD51 paralog B | 0.0281713 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0280117 |
| PCBP2 | poly(rC) binding protein 2 | 0.0280054 |
| MX1 | MX dynamin-like GTPase 1 | 0.0277827 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.027682 |
| CALR | calreticulin | 0.0276646 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.027629 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0274954 |
| MUC16 | mucin 16, cell surface associated | 0.026542 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0263672 |
| ENO1 | enolase 1, (alpha) | 0.0260956 |
| MECOM | MDS1 and EVI1 complex locus | 0.0259538 |
| CCNY | cyclin Y | 0.0257718 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0256511 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0253565 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0252384 |
| FNIP1 | folliculin interacting protein 1 | 0.0251421 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0246613 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0244702 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0242126 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0239129 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0235543 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0233404 |
| DSPP | dentin sialophosphoprotein | 0.023143 |
| FLNB | filamin B, beta | 0.0231402 |
| RBM47 | RNA binding motif protein 47 | 0.0230408 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0229747 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0226553 |
| TMF1 | TATA element modulatory factor 1 | 0.0225928 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.02233 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.022296 |
| ITGB6 | integrin, beta 6 | 0.0222265 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0219929 |
| PKM | pyruvate kinase, muscle | 0.0219155 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0218558 |
| ITGA6 | integrin, alpha 6 | 0.021818 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0217609 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0216056 |
| PRELID2 | PRELI domain containing 2 | 0.0215865 |
| RIOK3 | RIO kinase 3 | 0.021462 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0214284 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0214133 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0213635 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0211752 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0210851 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0207961 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0206765 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0206596 |
| MUC4 | mucin 4, cell surface associated | 0.0204434 |
| EHBP1 | EH domain binding protein 1 | 0.0203029 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0201186 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0198385 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.019771 |
| DGKH | diacylglycerol kinase, eta | 0.019535 |
| PLAC8 | placenta-specific 8 | 0.0194859 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0194027 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0193352 |
| TPI1 | triosephosphate isomerase 1 | 0.0192805 |
| TMEM123 | transmembrane protein 123 | 0.0191045 |
| MYOF | myoferlin | 0.0189649 |
| EXOC4 | exocyst complex component 4 | 0.0189239 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0188347 |
| SULF2 | sulfatase 2 | 0.018786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215554 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.105442 |
| RPS6 | ribosomal protein S6 | -0.0896407 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0702738 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0644003 |
| RPL35A | ribosomal protein L35a | -0.0635676 |
| RPL23 | ribosomal protein L23 | -0.0615579 |
| RPS8 | ribosomal protein S8 | -0.0611026 |
| RPLP1 | ribosomal protein, large, P1 | -0.0609398 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0488149 |
| ACTG1 | actin gamma 1 | -0.0485246 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0453462 |
| RPL12 | ribosomal protein L12 | -0.0448033 |
| RPL19 | ribosomal protein L19 | -0.0437851 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0436586 |
| RPS13 | ribosomal protein S13 | -0.0420696 |
| RPL34 | ribosomal protein L34 | -0.041157 |
| RACK1 | receptor for activated C kinase 1 | -0.0396655 |
| RPS15 | ribosomal protein S15 | -0.0389186 |
| LAMA4 | laminin, alpha 4 | -0.0386664 |
| WWC1 | WW and C2 domain containing 1 | -0.0371975 |
| PTMA | prothymosin, alpha | -0.0366195 |
| RPS19 | ribosomal protein S19 | -0.0364317 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0361598 |
| RPS21 | ribosomal protein S21 | -0.0357345 |
| TJP1 | tight junction protein 1 | -0.0350025 |
| RPL28 | ribosomal protein L28 | -0.034939 |
| MT2A | metallothionein 2A | -0.0343034 |
| RPS24 | ribosomal protein S24 | -0.0342917 |
| HLA-B | major histocompatibility complex, class I, B | -0.0331055 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0326845 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0324826 |
| RPL30 | ribosomal protein L30 | -0.0324491 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0319344 |
| RPL37 | ribosomal protein L37 | -0.0317355 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0316422 |
| RPL8 | ribosomal protein L8 | -0.0316135 |
| RPS23 | ribosomal protein S23 | -0.0315856 |
| HMGA1 | high mobility group AT-hook 1 | -0.0313909 |
| RPL26 | ribosomal protein L26 | -0.0311929 |
| RPL37A | ribosomal protein L37a | -0.0308118 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0295791 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0295554 |
| RPL31 | ribosomal protein L31 | -0.0292619 |
| RPS3 | ribosomal protein S3 | -0.028447 |
| RPLP2 | ribosomal protein, large, P2 | -0.0277723 |
| FTL | ferritin, light polypeptide | -0.0273154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272651 |
| RPL11 | ribosomal protein L11 | -0.0262831 |
| RPL9 | ribosomal protein L9 | -0.0261495 |
| THBS1 | thrombospondin 1 | -0.0257238 |
| FAM3C | family with sequence similarity 3, member C | -0.0256812 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0253517 |
| RPS27A | ribosomal protein S27a | -0.0251415 |
| RPS28 | ribosomal protein S28 | -0.0250611 |
| RPS29 | ribosomal protein S29 | -0.0250497 |
| GPHN | gephyrin | -0.024392 |
| RPL5 | ribosomal protein L5 | -0.0239978 |
| RPL32 | ribosomal protein L32 | -0.0239888 |
| RPS25 | ribosomal protein S25 | -0.023778 |
| RPS5 | ribosomal protein S5 | -0.0237344 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0236349 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0236064 |
| BRD2 | bromodomain containing 2 | -0.0235074 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.023484 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0232964 |
| TMSB10 | thymosin beta 10 | -0.0230426 |
| RYBP | RING1 and YY1 binding protein | -0.0229124 |
| RPS14 | ribosomal protein S14 | -0.0224357 |
| HLA-C | major histocompatibility complex, class I, C | -0.02207 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0220595 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0215997 |
| RPL38 | ribosomal protein L38 | -0.0215031 |
| RPS27 | ribosomal protein S27 | -0.0213579 |
| RPS16 | ribosomal protein S16 | -0.021353 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0210614 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0204931 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0202991 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0200166 |
| RPS20 | ribosomal protein S20 | -0.0197594 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0197484 |
| RPL27 | ribosomal protein L27 | -0.0197261 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0195661 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0195531 |
| MYO6 | myosin VI | -0.0192939 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0192601 |
| RPL36 | ribosomal protein L36 | -0.0190953 |
| RPS17 | ribosomal protein S17 | -0.018721 |
| SIK3 | SIK family kinase 3 | -0.0186646 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0186373 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.018575 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0185243 |
| H3-3B | H3.3 histone B | -0.0184926 |
| G0S2 | G0/G1 switch 2 | -0.0180364 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0180035 |
| RPL35 | ribosomal protein L35 | -0.0179241 |
| S100A10 | S100 calcium binding protein A10 | -0.0178599 |
| RPL36A | ribosomal protein L36a | -0.0177676 |
| S100A9 | S100 calcium binding protein A9 | -0.0174851 |
| RPLP0 | ribosomal protein, large, P0 | -0.0174614 |
